Munevver Serdarogullari @SCobanMune

Senior Embryologist-Weight Lifter @ESHRE5 20' YA #ESHREjc editorial team @ESHRE Nur&Mid Cert Com @ESHRE_IRHEC Social Media @ESHRE Male Repro Health Initiative eshre.eu/Publications/J… CypRus Joined April 2012

Tweets

12K
Followers

2K
Following

1K
Likes

21K

George Liperis @GLiperis

3 weeks ago

Not to be missed! Register and learn how your centre can become accredited as a training centre for Embryology ⬇️

ESHRE @ESHRE

3 weeks ago

Not to be missed! Register and learn how your centre can become accredited as a training centre for Embryology ⬇️

0 1 4 698 0

Download Image

0 1 7 153 0

George Liperis @GLiperis

7 months ago

Q3 of the #ESHREjc is underway on double vitrification and biopsy 👇🏻

Zoya Ali @zoyaalii_

7 months ago

Q3 of the #ESHREjc is underway on double vitrification and biopsy 👇🏻

17 0 6 1K 0

Download Gif

1 1 1 181 0

Andrew the Embryologist @AndrewIVFSAS

7 months ago

Embryo quality here is a key one. Two biopsies of a C grade trophectoderm biopsy is a much bigger proportion of an embryo than 2 of grade A! #eshrejc

Alessandra Alteri @alteri_ale

7 months ago

Embryo quality here is a key one. Two biopsies of a C grade trophectoderm biopsy is a much bigger proportion of an embryo than 2 of grade A! #eshrejc

1 0 2 405 0

1 1 11 315 1

Juanjo Fraire-Zamora @juanjo_fraire

7 months ago

@AndreaBrackner @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @alteri_ale @debsmtj @AndrewIVFSAS True! But we (as a community) have to decide which protocols should be automated 😅 there might be some patients/embryos that might not benefit from a one-size fits all approach 😖 and might need the hand of skillful embryologists 🤓💪🏼 #ESHREjc

0 1 6 150 0

George Liperis @GLiperis

7 months ago

@kashish__ @ESHRE Loading volume during tubing can also make a difference when it comes to amplification failure #ESHREjc

2 1 4 81 0

George Liperis @GLiperis

7 months ago

@kashish__ @ESHRE I would also add quality of the cells obtained from the biopsy. Excluded cells from the blastocyst that tend to degenerate might not get a signal. The ‘sight’ of zona opening can make a difference #ESHREjc

1 1 4 78 1

Munevver Serdarogullari @SCobanMune

7 months ago

@GLiperis 🎯In this paper, it is very detailed #eshrejc academic.oup.com/molehr/article…

0 1 2 89 0

Andrea Brackner @AndreaBrackner

7 months ago

@juanjo_fraire @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @alteri_ale @debsmtj @AndrewIVFSAS Future: Difficult as standarizarion of protocols across clinics is necessary and they currently rely on manual techniques and operation skills. However... automation and the use of AI/robotics in the IVF lab could offer some solutions for heterogeneity in the future. #ESHREjc

1 2 3 129 0

Andrew the Embryologist @AndrewIVFSAS

7 months ago

Whilst we can standardise protocols, we cannot standardise the actual biopsy. How many times does your method change depending on how difficult the blastocyst is to biopsy? #eshrejc

Omar Ammar @OmarRawi89

7 months ago

Whilst we can standardise protocols, we cannot standardise the actual biopsy. How many times does your method change depending on how difficult the blastocyst is to biopsy? #eshrejc

0 0 2 416 0

1 2 8 301 0

George Liperis @GLiperis

7 months ago

@kashish__ @ESHRE 2. Each episode of pipetting between receptacles, or observation (outside the controlled incubation environment), can introduce mechanical or environmental stresses and increase risk of incident or accident, albeit small. DOI: 10.1017/S2040174417000368 #ESHREjc

0 1 5 61 0

Juanjo Fraire-Zamora @juanjo_fraire

7 months ago

@alteri_ale @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @debsmtj @AndrewIVFSAS Definetly! It is important to note that meta-analyses are capped by the quality of retrospective studies and outcomes 😖 #ESHREjc

1 1 3 123 0

Alessandra Alteri @alteri_ale

7 months ago

@kashish__ @ESHRE Embryological and lab factors including insufficient cell number (<5 TE cells), excessive laser use or mechanical damage, contamination, poor quality blastocysts #ESHREjc

1 1 5 118 0

George Liperis @GLiperis

7 months ago

Q2 of the #ESHREjc is underway! What are the sources of amplification failure?

Kashish Sharma @kashish__

7 months ago

Q2 of the #ESHREjc is underway! What are the sources of amplification failure?

11 4 7 1K 1

3 1 3 184 0

Kashish Sharma @kashish__

7 months ago

#ESHREjc Q2. Authors have found an effect on clinical outcomes when double biopsy 🧬🧬 and double ❄️❄️ was performed. 🌀What are the sources of amplification failure from a genetics🧬/embryological background❓️❓️ @ESHRE

11 4 7 1K 1

KeertiS @keertisinghis

7 months ago

@juanjo_fraire @cimsit @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @alteri_ale @debsmtj @AndrewIVFSAS I think large cohort studies are needed to study the relationship between miscarriages following double biopsy+double vitrification

0 1 2 156 0

Andrea Brackner @AndreaBrackner

7 months ago

@juanjo_fraire @GLiperis @OmarRawi89 @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @alteri_ale @debsmtj @AndrewIVFSAS 1. Limitations of Retrospective datasets: introduction of potential bias. 2. Variability in biopsy/vitri protocols. 3. Maybe neonatal outcomes underreported?

1 1 2 184 0

Omar Ammar @OmarRawi89

7 months ago

@juanjo_fraire @GLiperis @SCobanMune @zoyaalii_ @kashish__ @BasselWattar @alteri_ale @debsmtj @AndrewIVFSAS For this particular paper, variations in SOPs and all IVF cycle details within each study analyzed could actually influence results. I think a multi center RCT with a strict protocol would be very beneficial! #ESHREjc