Rahul Samant @SamantLab
Group Leader @BabrahamInst. He/him. All things #ubiquitin #proteostasis #proteomics #ageing #senescence. Spend too much on food & wine. Opinions mine, all mine! samantlab.github.io Cambridge, UK Joined March 2012-
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Rahul Samant retweeted
Now online! A split-site E3 ligase mechanism enables ZNFX1 to ubiquitinate and cluster single-stranded RNA into ubiquitin-coated nucleoprotein particles dlvr.it/TMms3Y
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Rahul Samant retweeted
Cellular senescence is a therapeutic target for cancer and central nervous system disorders. Here are two reviews on progress and challenges: nature.com/articles/s4157… (Readcube rdcu.be/eCTbQ) nature.com/articles/s4157… (Readcube rdcu.be/eCTbB) #ARDD2025
Rahul Samant retweeted
Cytosolic DNA crosstalk in senescence: a new axis of inflammatory signaling-------I'm excited to collaborate with Joao Passos, John Sedivy, Zhixun Dou @nneretti to understand mechanisms and interventions targeting cytoplasmic chromatin in senescence embopress.org/doi/full/10.10…
Rahul Samant retweeted
Join us for a Public Panel discussion on Current & Future Treatments for Dementia, featuring experts in the field 🧠 No need to register - just come along and spread the word! 📍West Road Concert Hall, Cambridge 🗓️11th Sep 5-6:30pm BST Sponsored by Beckman Coulter
Rahul Samant retweeted
Apoptotic vesicle release from a cell as it gives up the ghost under oxidative stress, as seen by MOSAIC lattice light sheet mode.
Rahul Samant retweeted
A chaperone-proteasome-based fragmentation machinery is essential for aggrephagy: nature.com/articles/s4155…..
Rahul Samant retweeted
Proximity-specific ribosome profiling using LOV-BirA reveals two distinct strategies for mitochondrially-localized translation: one for long coding sequences and one for short. It was a pleasure to contribute to this beautiful work from Jonathan Weissman @JswLab and @JingchuanLuo…
Rahul Samant retweeted
"The day the paper was published should have been a moment of pride. Instead, it felt like a quiet erasure." #ScienceWorkingLife scim.ag/4oPJkeg
Rahul Samant retweeted
🚀New adventures in #DrugDiscovery: We designed multitarget leads that hit Hsp70, Hsp90 & Cdc37 at once—disrupting chaperone networks that fuel tumor growth. Collaboration with @MedMol, @GestwickiLab Labs #CancerResearch #CompChem @AirC @Structure_CP shorturl.at/gGk7m
Rahul Samant retweeted
I am excited to share that I will join the Friedrich Miescher Institute @FMIscience in Basel as a group leader, starting in March 2026 🎉 We will explore cell fate regulation during organogenesis, with a focus on how cell elimination underlies the emergence of functional tissues.
Rahul Samant retweeted
Come join us for the next monthly on-line seminar (5th September, 1 pm BST) aimed to connect the UK Biomolecular Condensate community (All are welcome to come and listen). @TS_Lab_ @BosseStefansson @PhysicsofLifeUK
Rahul Samant retweeted
Online Now: A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision dlvr.it/TMgxVZ
Rahul Samant retweeted
We have an opening for a Research Assistant with the Rahman Group Opening closes on 15 September Apply here: phar.cam.ac.uk/jobs/researc...
Rahul Samant retweeted
Episodic transport of protein aggregates achieves a positive size selectivity in aggresome formation: nature.com/articles/s4146…
Rahul Samant retweeted
We're Hiring! Assistant Professor of Immunology and Molecular Medicine in MCB. Learn more and apply online: aprecruit.berkeley.edu/JPF05096
Rahul Samant retweeted
Our newly updated yICSA website is here! cellsenescence.info/yicsa Check out our activities & stay tuned for updates. Next stop: a special session at the 10th Annual @ICSA_senescence 🇮🇹 meeting in Rome!
Rahul Samant retweeted
🚨 Excited to share my PhD work from @AOri_lab’s at @LeibnizFLI Jena, now out as a preprint on @biorxivpreprint biorxiv.org/content/10.110… A glimpse into how redox biology shapes brain proteostasis and aging 🧠🧬👇
Rahul Samant retweeted
Very proud of my PhD student (and friend!) @CarlaSalomoColl from Simon Wilkinson lab at @EdinburghUni! Her first author publication is out in Dev Cell: cell.com/developmental-… Really interesting study, a must read!
Rahul Samant retweeted
How bad is it if a protein gets entangled? It (mostly) boils down to length, as Ed O'Brien's lab @psu_chemistry and @fried_lab show in our latest paper out in @ScienceAdvances. Short explainer thread 1/8 science.org/doi/full/10.11…
Rahul Samant retweeted
If you’re enjoying some calm while others are on holiday, here’s a #NEW #preprint to dive into — led by the brilliant @viennabiocenter student @Alibequelous: 👇A quick 🧵+ link: biorxiv.org/content/10.110…
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