SempleLab @SempleLab
The Semple Lab is interested in understanding the causes and consequences of abnormal insulin action in human disease. @EdinburghUni Edinburgh, Scotland Joined September 2018-
Tweets55
-
Followers240
-
Following69
-
Likes32
We have two postdoc jobs available in the Semple Lab. The second focuses on DNA damage & repair in the context of metabolic disease: elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…
We have two postdoc jobs available in the Semple Lab. The first focusses on evaluating insulin resistance using in vivo and in vitro models: elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…
Submit your abstracts now for the Frontiers of Endocrinology research topic 'Mitochondrial Dysfunction in Metabolic Diseases'. One of our fab postdocs, Ineke, is an editor: frontiersin.org/research-topic…
We had a fantastic lab away day this week, visiting the Isle of May. The first time seeing many lab members in person this year! Scotland treated us with some glorious sunshine and lots of seals, puffins and many other amazing birds. Can you spot the puffins in our photo?
Important read about bone health after bariatric surgery Bone Complications of Bariatric Surgery: Updates on Sleeve Gastrectomy, Fractures, and Interventions in: European Journal of Endocrinology - Ahead of print eje.bioscientifica.com/view/journals/…
Interesting and thoroughly argued mechanistic speculation - well worth a read. MECHANISMS IN ENDOCRINOLOGY: Vitamin D and COVID-19 in: European Journal of Endocrinology - Ahead of print eje.bioscientifica.com/view/journals/…
Back in the lab! 🧫 🔬 Huge thanks to the staff @MRL_Cam that worked so hard to enable the Institute to open and allow us to continue our research! Right, where are those antibodies... 🧪
A massive congratulations to @RalitsaMadsen, our most recent lab alumnus, for being awarded a Sir Henry Wellcome Postdoctor Fellowship award.
Just had two more excellent talks in our virtual #PhD and #Postdoc seminar series, with Ineke Luijten and Vahid Aslanzadeh from @SempleLab presenting their latest research. Great attendance and Q&A from @EdinUniCVS members!
Our first online lab meeting completed this morning! Can you spot Ineke and Eleanor's 'deep in thought' faces?
For #labscientists in #Edinburgh who want to help.
Congratulations, yet again, to our post doc Ineke Luijten for winning ‘Best doctoral thesis’ in the Department of Molecular Biosciences @Stockholm_Uni
Had lots of fun making a model of fat tissue this afternoon for @EdSciFest
A belated congratulations to our postdoc Ineke Luijten for being awarded an international post doc grant from the Swedish research council to fund her research for the next 3 years @Vetenskapsradet
A photo from our lab away day at @peebleshydro last October. A great day of scientific discussion and lab bonding - nothing unites a group of scientists like taking aim at @rksemple
Fascination and trepidation pursuing findings outside lab's comfort zone - but thanks to talented postdoc @RalitsaMadsen and great collaborators most recent PI3K work now preprinted, implicating TGFbeta signalling in oncogenic PI3K-driven stemness biorxiv.org/content/10.110…
Sadly, we have daily reminders of how scientists stretch limits of credulity, exaggerate, and embelish, to gain attention and move up the ladder. The public is not easily fooled. This behaviour diminishes trust in science, & breeds cynicism, climate change deniers and anti-Vaxers
Sadly, we have daily reminders of how scientists stretch limits of credulity, exaggerate, and embelish, to gain attention and move up the ladder. The public is not easily fooled. This behaviour diminishes trust in science, & breeds cynicism, climate change deniers and anti-Vaxers
Recurring Public Service Announcement-When we breathlessly hype our protein, gene, pathway via mouse data as heralding a "potential new therapeutic target", there is a 99.9% chance we are wrong. Wonder why science has a massive credibility problem? It starts with all of us
An unfortunate consequence of the arms race of scientists overhyping their work is that those manuscripts now written in a cautious & honest way acknowledging previous findings & taking care not to oversell are often editorially rejected for "not being very exciting or novel".

Will Cawthorn @BMATscientists
1K Followers 909 Following Principal Investigator @EdinUniCVS, studying #BoneMarrowAdiposeTissue (BMAT), caloric restriction, ageing & sex differences. Also #LERU #OpenScience Ambassador
Inst Metabolic Scienc... @IMS_MRL
3K Followers 333 Following Institute of Metabolic Science-Metabolic Research Labs. Research into diabetes, obesity and related endocrine and metabolic disorders.
Giles Yeo @GilesYeo
26K Followers 903 Following MBE; Professor @Cambridge_Uni @WolfsonCam, food intake & #obesity; Broadcaster; Author, #WhyCaloriesDontCount out now; on Instagram & Threads @gilesyeo
stephen o'rahilly (it... @StephenORahilly
10K Followers 367 Following Physician-scientist interested in the causes and adverse consequences of obesity. Director MRC Metabolic Diseases Unit, University of Cambridge. Views mine.
Jim Johnson, PhD @JimJohnsonSci
13K Followers 8K Following Mentor, Physiologist, Prof / Assoc. Director, charity cofounder, exPharmaVP, Dad, HockeyGuy. Views≠employer's RT≠endorse he/him/ same handle on Bluesky
Georgios Krilis @DrGeoKrilis
260 Followers 577 Following Postdoctoral Fellow, PhD in Cardiovascular Science (He /Him)
EdinUniCVS @EdinUniCVS
2K Followers 911 Following The BHF/University of Edinburgh Centre for Cardiovascular Science (CVS) is a research centre in the College of Medicine & Veterinary Medicine
Daniel Fazakerley @DPhaz
816 Followers 667 Following Group leader at @IMS_MRL researching insulin action and glucose transporter traffic.
Peter Aldiss, PhD @Peter_Aldiss
3K Followers 5K Following Junior Group Leader and Nottingham Research Fellow @UoNBDI @NottmBRCLiverGI @UniofNottingham
FrezzaLab @FrezzaLab
27K Followers 3K Following We are a group of metabolism-lovers, focused on mitochondrial metabolism. Tweets are from Christian. https://t.co/EbWsJo6DnZ
Florian T. Merkle PhD... @FlorianMerkle
2K Followers 932 Following Group leader at @Cambridge_Uni using stem cells to study metabolic & neurodegenerative disease, & the links between them. Moving to: https://t.co/13VB41w9AM
Guillaume Canaud (MD,... @CanaudLab
2K Followers 670 Following Translational medicine. Hôpital Necker Enfants Malades/Université Paris Cité.
Cathy Abbott @CathyAbbottLab
6K Followers 4K Following Professor, eEF1A2/neurological disorders. Tweeting about research, EDI, 3Rs (AWERB chair). She/her, views own. @cathyabbott.bsky.social
Lee Roberts @Roberts_Lab
1K Followers 720 Following Professor of Molecular Physiology and Metabolism, University of Leeds. Diabetes, obesity, heart failure, metabolism, adipose, exercise and muscle.
Rachel Bell @bell_rachel_
292 Followers 411 Following Postdoc with Denby Lab | Interested in myeloid cells, fibrosis and kidney disease 🫘
EdinUniMetabolism @EdinUniMetabol
706 Followers 461 Following We are a PI-led Theme researching Metabolism, Obesity and Diabetes within the Centre for Cardiovascular Science at the University of Edinburgh
Jake P. Mann @jakepmann
2K Followers 1K Following @jakepmann.bsky.social Clinician-scientist. ACL Paediatric hepatology. Rare/genetic liver diseases. Dad. Ultrarunner.
Phillip J White PhD @phillipwhite14
3K Followers 4K Following Metabolic Physiology Enthusiast Come KIC it with the White-McGarrah Lab @Duke Molecular Physiology Institute. #METPHYS
Harold Pimentel @hjpimentel
5K Followers 1K Following Assistant Prof @CompMedUCLA & Human Genetics. Genes, RNA, and computation. One fewer hands than the mode. HHMI Hanna H. Gray Fellow. He/him.
Anna @Annie_PerlGirl
615 Followers 3K Following
Ian McCracken @IanMcCracken15
138 Followers 425 Following BHF Immediate Research Fellow @IdrmOxford | University of Oxford | Interested in all things cardiac development and regeneration
Rugved Rane @RugvedRane16
1 Followers 37 Following
Andi Ratih @AyuAndiRatih
76 Followers 229 Following Takara Bio Europe Territory Manager for Scotland. PhD in life science. Enjoy helping scientists finding best solutions, cooking, voyage and kids pedagogy.
Jacob Zq @ZqJacob41328
2 Followers 107 Following
Nienke Willemsen (she... @nwillemsen95
228 Followers 315 Following Post-doc @Sancholab | Alum @BarteltLab | Cell metabolism & Proteostasis
Louise Clark @Louisefclark
130 Followers 396 Following
Rossella Labella @rossellalab88
2K Followers 5K Following Postdoc Edward P. Evans Center for MDS fellow in @SKousteni, @Columbia, RA @ndorms in @KusumbeLab, PhD @SapienzaRoma Scientific Board Member of @BMA_Society
Neil Vasan @NeilVasan
2K Followers 1K Following Physician-scientist and Director of Breast Cancer Translational Research @NYULangone | Studying cancer signaling and genomics | Father of 4 | Tweets my own
Baker Lab @bakergroupcvs
468 Followers 217 Following Translational cardiovascular research group in @EdinUniCVS | We are interested in vascular damage, repair, and cell/gene/RNA-based therapies.
Yasmina kahoul @MinaKahoul
12 Followers 343 Following In the end we only regret the chances we didn't take !!!
Jenna Ziebell @ziebs83
606 Followers 1K Following Senior lecturer @WickingDementia Centre @UTas_ | Microglia researcher | Group leader | #womeninSTEM | Mother | Sports enthusiast
Diabetologia @DiabetologiaJnl
20K Followers 2K Following We publish high-quality, cutting edge articles on all aspects of diabetes, from basic science through translational work to clinical research
Leonie Heilbronn @LeonieHeilbronn
154 Followers 87 Following
Bevan Main, Ph.D. @bevo_07
566 Followers 949 Following Georgetown University- TBI and Concussion. Australian ex-pat
Simon Platt @Si_Platt
67 Followers 265 Following
Katherine Thomasset @Kaththomasset
414 Followers 1K Following Medical copy-editor @DiabetologiaJnl @BristolUni She/her All views are my own
Neha Agrawal @_neha_agrawal
322 Followers 1K Following Lecturer and PI @SBSatEd @EdinburghUni, Interested in metabolic disease, Systems physiology, #Drosophila, Formerly @andreabrandlab @LeopoldLab.
Bitesize Bio @BitesizeBio
3K Followers 870 Following Bitesize Bio helps bioscience researchers to grow by collating personal experience, advice, practical tools, and wisdom from experienced mentors.
Kerrie Thackray @KerrieThackray
512 Followers 2K Following Diabetes consultant (via a big career break), expat Scot, Brownie leader, mother, #T1Dmum
Michael Mindrum, MD @MichaelMindrum
10K Followers 2K Following Internal Medicine & obesity specialist. Interests in diabetes, behavioral psychology, consciousness, AI. Born in 🇺🇸, 🇨🇦 is home.
KuanChan Chen @KuanChanChen
7 Followers 45 Following PhD student in Dr William Cawthorn's group @EdinburghUni Taiwan Clinical Attending Physician at TSGH (Endocrinology & Metabolism)
Beacon for Rare Disea... @RareBeacon
12K Followers 10K Following Beacon is a UK-based charity that is building a united rare disease community with patient groups at its heart. Previously known as Findacure.
Alice Williamson @AC_Williamson
177 Followers 435 Following Postdoc @QMUL leveraging human genomics to understand complex diseases 👩🏻🔬👩🏻💻| Previously PhD student @IMS_MRL @MRC_Epid | Views my own
Alelí 🍉 @_alh3li
203 Followers 1K Following Mi alma que desborda humanidad ya no soporta tanta injusticia.
Gram Hansen Lab @gram_lab
606 Followers 1K Following "Starting to migrate to the other site".. gram-lab Hippo Pathway, Caveolae, Cancer, Regeneration, Immigrant. Tweets by PI Views ≠ employers' RT ≠ endorse
Review Commons @ReviewCommons
5K Followers 1K Following A platform by @EMBO and @ASAPbio_ that provides independent peer review before journal submission for Refereed Preprints
Andrea @AndreavDam
129 Followers 403 Following Clinical biochemist in training, fascinated by adipocytes.
Rongling Wang @RonglingWang
89 Followers 235 Following 👩🏻🔬Postdoc researcher in Charité hospital 🇩🇪Berlin—HFpEF 👩🏻🎓PhD in Metabolism atUniversity of Edinburgh 🇬🇧 🏴 Love ❤️ painting 👩🏻🎨
Coghlan @Coghlan85242154
7 Followers 49 Following
Danielle McAllister @Daniell00400107
0 Followers 47 Following
Nadine Sommer @din_sommer
87 Followers 162 Following @EastbioDTP PhD Student @rowett_abdn • Investigating Lipodystrophy, Fatty Liver and Type II Diabetes • Wildlife Lover & Hobby Birder • Views are mine
Aberdeen Cardiovascul... @AberdeenCDC
911 Followers 1K Following 1) to enhance cardiovascular & diabetes patient care through research, education & communication 2) to reduce risk, develop new treatments, improve diagnoses.
Peter Smith @psmiddy12
97 Followers 541 Following
Junxi Wu @Junxi81909976
127 Followers 305 Following Vascular biology, functional tissue engineering, and tansplantable organ construct.
Syeda Anchel Zahra @AnchelZahra
227 Followers 2K Following PhD Student at the German Institute of Human Nutrition, Potsdam-Rheubreucke
Fabiola Monteiro @Fabiola51356829
17 Followers 77 Following
Euro J Endocrinology @EJEndo
9K Followers 1K Following EJE contains clinical and translational research and reviews on #endocrinology. The journal of @ESEndocrinology and published by @OxUniPress
5minofscience @5minofscience
1K Followers 3K Following Connecting researchers and industry | #scicomm | #blackintheivory
Will Cawthorn @BMATscientists
1K Followers 909 Following Principal Investigator @EdinUniCVS, studying #BoneMarrowAdiposeTissue (BMAT), caloric restriction, ageing & sex differences. Also #LERU #OpenScience Ambassador
John Speakman @JohnSpeakman4
12K Followers 665 Following Scientist working in China and the UK. Studies energy balance: esp #obesity and #ageing. Likes #photography #wildlifephotography. Co-EiC: @lifemetabolism2
Inst Metabolic Scienc... @IMS_MRL
3K Followers 333 Following Institute of Metabolic Science-Metabolic Research Labs. Research into diabetes, obesity and related endocrine and metabolic disorders.
Giles Yeo @GilesYeo
26K Followers 903 Following MBE; Professor @Cambridge_Uni @WolfsonCam, food intake & #obesity; Broadcaster; Author, #WhyCaloriesDontCount out now; on Instagram & Threads @gilesyeo
stephen o'rahilly (it... @StephenORahilly
10K Followers 367 Following Physician-scientist interested in the causes and adverse consequences of obesity. Director MRC Metabolic Diseases Unit, University of Cambridge. Views mine.
Jim Johnson, PhD @JimJohnsonSci
13K Followers 8K Following Mentor, Physiologist, Prof / Assoc. Director, charity cofounder, exPharmaVP, Dad, HockeyGuy. Views≠employer's RT≠endorse he/him/ same handle on Bluesky
EdinUniCVS @EdinUniCVS
2K Followers 911 Following The BHF/University of Edinburgh Centre for Cardiovascular Science (CVS) is a research centre in the College of Medicine & Veterinary Medicine
Ozanne lab @ozannelab
2K Followers 760 Following Lab of Prof Sue Ozanne, Director of @ims_mrl . We study how the environment during pregnancy & early life programs metabolic & cardio disease risk
Peter Aldiss, PhD @Peter_Aldiss
3K Followers 5K Following Junior Group Leader and Nottingham Research Fellow @UoNBDI @NottmBRCLiverGI @UniofNottingham
FrezzaLab @FrezzaLab
27K Followers 3K Following We are a group of metabolism-lovers, focused on mitochondrial metabolism. Tweets are from Christian. https://t.co/EbWsJo6DnZ
Florian T. Merkle PhD... @FlorianMerkle
2K Followers 932 Following Group leader at @Cambridge_Uni using stem cells to study metabolic & neurodegenerative disease, & the links between them. Moving to: https://t.co/13VB41w9AM
Cathy Abbott @CathyAbbottLab
6K Followers 4K Following Professor, eEF1A2/neurological disorders. Tweeting about research, EDI, 3Rs (AWERB chair). She/her, views own. @cathyabbott.bsky.social
EdinUniMetabolism @EdinUniMetabol
706 Followers 461 Following We are a PI-led Theme researching Metabolism, Obesity and Diabetes within the Centre for Cardiovascular Science at the University of Edinburgh
Diabetes UK Research @DUK_research
6K Followers 647 Following Diabetes research news, involvement opportunities and more from the Research Team at @DiabetesUK
Jake P. Mann @jakepmann
2K Followers 1K Following @jakepmann.bsky.social Clinician-scientist. ACL Paediatric hepatology. Rare/genetic liver diseases. Dad. Ultrarunner.
AG @ResearchET
1K Followers 465 Following
Brendan Gabriel @DrBMGabriel
1K Followers 1K Following Muscle metabolism and exercise physiology researcher. Working primarily with T2 Diabetes/obesity @AberdeenUni & @KarolinskaInst
Eleanor McKay, PhD @Eleanor_McKay_
116 Followers 196 Following Postdoctoral researcher in the @JourdainLab at @DIB_UNIL . Advocate for open science.
Kat Kentistou @aikat33
102 Followers 393 Following Postdoc @MRC_Epid & Affiliate @Newnham_College | Researching adiposity genetics.
Molecular Metabolism @MolMetab
10K Followers 373 Following Molecular Metabolism is an open access journal reporting breakthroughs with the potential for transformative impact on today's metabolism research.
EURORDIS-Rare Disease... @eurordis
32K Followers 1K Following An alliance of over 1,000 patient organisations working across borders and diseases to improve the lives of all people living with rare diseases.
Richard Kay @Rlchardkay
307 Followers 372 Following Passionate about the application of mass spectrometry to disease diagnosis. Special interest in plasma peptidomics. Oh - and an average triathlete 😆
Pierre Vabres (moi/je... @pierrevabres
3K Followers 3K Following Academic Pediatric Dermatologist & Mosaicist AIHP https://t.co/Kjton6B5LE
Cecilia Lindgren @ceclindgren
8K Followers 917 Following Co-founder, CSO @Aneira.Health, Professor @ Oxford University. Proud mom of 3. Wellcome Trust Investigator. Promoting equality. Love 🦈. #🕷🕸💙
Michael Ristow, MD @Prof_M_Ristow
7K Followers 7K Following Director, Inst. for Exp. Endocrinology @ChariteBerlin; views are my own; also @ https://t.co/SmQzlqyvly & https://t.co/vUfyqMWlFh
Frontiers - Endocrino... @FrontEndocrinol
5K Followers 390 Following Research and updates from all @FrontiersIn journals in the field of endocrinology. #openaccess
The Mosaic Team - "Le... @GAD_Mosaic
104 Followers 81 Following Home of M.U.S.T.A.R.D. Clinical, therapeutic and genetic research on skin mosaicism in Dijon 🇫🇷 https://t.co/G2OptBGWA4
Beacon for Rare Disea... @RareBeacon
12K Followers 10K Following Beacon is a UK-based charity that is building a united rare disease community with patient groups at its heart. Previously known as Findacure.
Rare Disease UK @rarediseaseuk
21K Followers 2K Following National campaign run by @GeneticAll_UK to improve the lives of those affected by rare conditions and all who support them. #RareDisease.
Helen Simpson @hormone_doc
5K Followers 2K Following do what is right not what is easiest|general badass|endocrine massive|data driven|work hard|play hard
Cambridge Rare Diseas... @camraredisease
8K Followers 6K Following making #rarediseases an everyday conversation https://t.co/kZWskP9Ojj
Helle Jørgensen @Helle_123
153 Followers 95 Following Biomedical researcher, cell plasticity in cardiovascular health and disease, tango dancer and gardener - Helle Jørgensen lab @hfj22 https://t.co/3Cwg8jRWVk…
CMVMECR @ECRCMVM
741 Followers 352 Following This account is no longer active. Follow us on our channels here: https://t.co/5LVYpdKfHz
Fast Track Impact @fasttrackimpact
38K Followers 46 Following Get more impact. Get your time back. Get inspired. Make a difference! For more research impact news, also follow: @profmarkreed; @JensenWarwick; @IMI_Methods
Robert Kiley @robertkiley
3K Followers 238 Following Head of Strategy, cOAlition S. Interested in making research outputs open & usable. Enjoy walking Dug, cooking & being with my family
Jeffrey Flier @jflier
30K Followers 3K Following Harvard University Distinguished Service Professor and Higginson Professor of Physiology and Medicine at Harvard Medical School. Former Dean of HMS.
GoPI3Ks (Genetic Over... @GoPI3Ks
567 Followers 354 Following A UK registered charity (1176289) for those living with PROS (PIK3CA Related Overgrowth Spectrum)
Jacek Mokrosiński @jmokrosinski
510 Followers 1K Following pharmacologist interested in molecular mechanisms regulating body weight and metabolism | 🇵🇱🇪🇺🇬🇧 in 🇺🇸| 🏳️🌈 he/him
bxv_canc @bxv_canc
165 Followers 35 Following Alert for pre-print manuscripts on Cancer biology research, sources bioarxiv #openaccess #cancer #oncology (photo @IRPatNIH) by @wpgilks
Overgrowth Study @OvergrowthStudy
143 Followers 121 Following We are scientists and doctors studying segmental overgrowth, aiming to improve understanding & diagnosis rates, and to identify better treatments in the future.
Mark Evans @MEvansCambridge
1K Followers 460 Following Academic, clinician working in type 1 diabetes..World’s worst carb counter
Endocrine Society @TheEndoSociety
32K Followers 3K Following We unite, lead, and grow the global endocrine community to accelerate scientific breakthroughs and improve health worldwide. @endocrinesociety.bsky.social
DRWF @DRWFDiabetes
3K Followers 3K Following We fund vital research that is helping advance our understanding of diabetes and its complications 🔬❤️
Gemma.V.Brierley @GV_Brierley
174 Followers 451 Following Principal Investigator focused on insulin resistance. Cyclist, photographer and runner (when not broken).
Academy of Medical Sc... @acmedsci
34K Followers 2K Following Independent expert voice of biomedical and health research in the UK, fostering good health for all supported by the best research.
The Francis Crick Ins... @TheCrick
55K Followers 1K Following We’re the Crick, a research institute in London. We’re no longer posting on this account, but you can find other ways to stay in touch in our pinned post.
National Institute fo... @NIHRresearch
97K Followers 4K Following Sharing news and information from the National Institute for Health and Care Research (NIHR). We fund, enable and deliver world-class health and care research.
Biotechnology and Bio... @BBSRC
56K Followers 1K Following UKRI BBSRC invests in world-class bioscience research & training on behalf of the UK public. We are part of UK Research and Innovation (@UKRI_News).
Medical Research Coun... @The_MRC
86K Followers 1K Following UKRI MRC is dedicated to improving human health since 1913. Part of UK Research and Innovation @UKRI_News.
Prof Lora Heisler @LoraHeisler
1K Followers 156 Following Working to understand how obesity and type 2 diabetes develop in order to discover new treatments. Opinions are my own.
Justin Rochford @RochfordJJ
493 Followers 247 Following Working out how we make fat cells and using this information to understand lipodystrophy, obesity and type 2 diabetes. All views are my own.
Tomlinson Group @GroupTomlinson
260 Followers 170 Following Researching the Molecular and Steroid Hormone Biology mechanisms that modulate metabolic phenotype. Group Leader: Prof Jeremy W Tomlinson