Medical oncologist 🧬, believe in patient reported outcome measures (PROMs)🙂.
MBBS, MD medicine (TNMC & Nair hospital, Mumbai) DM medical oncology (JIPMER) Ahemdabad , Gujarat , India Joined October 2023
🔬MRD in #AML: Insights
by Dr. Radich
🧠Known Knowns:
MRD+ = Poor outcome vs. MRD-.
Flow: Fast, one number.
NGS: Sensitive detection.
CHIP complicates interpretation.
❓ Known Unknowns:
Optimal NGS VAF?
Mutation-specific MRD depth?
PB vs. BM for MRD?
My wishlist from #SantaClaus and from 2025 in oncology , as oncologist who practices in developing country like India 🇮🇳 , at community level and has a keen interest in analyzing data and is active on Social Media voicing opinion ( un filtered 😀 and un biased )
1- Let…
🚨 🆕 HCC #Guideline Alert🚨: The Role of #Radiotherapy by BCLC Stage from EASL Clinical Practice Guidelines on the management of
#hepatocellular carcinoma. A thread for the radiation oncology community 🧵🔥
Let’s break it down by BCLC stage!👇
It's fascinating to read about how microbials evolved drug resistance mechanism over the years in response to survival...nd now we are tried to learn every bit of it for the similar reasons...
AMR Awareness week. #WAAW2024
Excited to share our latest publication in @BloodCancerJnl
A simplified prognostic score using just age and albumin for patients with newly diagnosed Hodgkin Lymphoma
As always indebted to @DrPMPGI and @DrGPrakash for the mentorship
nature.com/articles/s4140…
70+ Senior Citizens of all income groups can now avail the benefit of ₹5 Lakh Free Treatment in all empaneled hospitals.
📞Call 14555 to know more about ‘Ayushman Vay Vandana Card’ for senior citizens.
#AyushmanBharat#VayVandanaCard#PMJAY@MoHFW_INDIA@PIB_India@PMOIndia
⁉️Might ICIs increase risk for viral infections???
🔥A study using FDA data reveals a significant link between CMV infections and the ipilimumab/nivolumab combo in cancer immunotherapy, even in immunocompromise-free patients.
⚡️⚡️This highlights the need to monitor for viral…
Tissue agnostic approvals from 2017 till now @myESMO .
Lets see the Other side of the coin.
1 - It is great to have Tissue Agnostic approvals and works well for NTRK fusion, B-RAF mutation and RET fusion and to some extent for MSI high .
But for HER2-3 plus and TMB high…
✓ Additional tumor debulking failed to improve OS for patients with mCRC
✓ Need for randomised phase 3 trials in lung/breast cancer too!
✓ Hellman's spectrum theory (oligometastasis) at real test!
✓ Need for predictive score for curative intent in oligometastatic pateints
Starglo - #EHA2024 plenary
- R-GemOx v Glofit-GemOx R/R DLBCL
- 2L (SCT-ineligible) / 3L+
- OS primary EP
- med OS 12.9mo (con) v 25.5mo
- More TEAEs but more Rx exposure
- More deaths but mainly COVID
- G1/2 CRS as expected
A practise changing study.
#lymsm
111 Followers 750 FollowingSometimes life just keep giving surprises.
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Keep smiling
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