Shukla Group @ShuklaGroup
Research Group @ChBE_Illinois, @Illinois_Alma shuklagroup.org Urbana, IL Joined June 2015-
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Really happy to have taken part as a Binding Illini in @ShuklaGroup!
Really happy to have taken part as a Binding Illini in @ShuklaGroup!
1/ š¬ Thrilled to share our new preprint: ESMDynamic: Fast and Accurate Prediction of Protein Dynamic Contact Maps from Single Sequences š Now on bioRxiv: biorxiv.org/content/10.110ā¦
ESMDynamic: Fast and Accurate Prediction of Protein Dynamic Contact Maps from Single Sequences 1. A novel study introduces ESMDynamic, a deep learning model that predicts dynamic residue-residue contact probability maps directly from protein sequences. This innovation leapfrogsā¦
How can we use biological datasets to accelerate design for synthetic biology applications? We developed an ML-driven, multi-objective frameworkāpowered by augmented directional tokensāto engineer proteins for specificity and selectivity. w/@ShuklaGroup biorxiv.org/content/10.110ā¦
With a new five-year, $15M award, the @NSF has renewed its support of the @Molecule_Maker Lab Institute, which develops AI tools for discovery and synthesis of molecules for uses in medicine, energy, industry and more. chbe.illinois.edu/news/stories/nā¦
Two for the Price of One: Integrating Large Language Models to Learn Biophysical Interactions 1. This study presents a framework to combine large language models (LLMs) to learn biophysical interactions, particularly focusing on binding affinity and specificity betweenā¦
Congratulations to professors Guironnet, Rogers and Shukla who have been named James W. Westwater professorial scholars in recognition of their excellence in teaching and research! Learn more: chbe.illinois.edu/news/stories/Gā¦
A cannabinoid bitopic, biased and peripheral agonist analgesic with limited tolerance and tetrad in Nature. Work led by @Vipin36590264 with @robgereau @DrorLab kaavya Krishna Kumar @WashUClinPharm @WashUanesthesia A short thread nature.com/articles/s4158ā¦
Love the beautiful illustrationš„°! Our work published @ScienceAdvances , featured by Daily Texan News! ē§éć®ęę°ć®ē ē©¶ęęććć¼ć«ć«å¤§å¦ę°čć«ć¦åćäøćććć¾ć暤 š¤š±š¦ "UT researchers discover communication between growth, immunity pathways in plants" thedailytexan.com/2025/02/19/ut-ā¦
Congratulations to CHBE Professor Ying Diao, one of three Illinois researchers who have received Presidential Early Career Awards for Scientists and Engineers.
.@ShuklaGroup & @diwakarshukla and colleagues report the transport mechanism of an alanine-alanine peptide through the PepTSo transporter by MD simulation nature.com/articles/s4200ā¦
Congratulations to Joseph Clark, undergraduate researcher in our lab and his mentor, Xuenan Mi for publication of their paper on peptide language model, PeptideESM! @MCB_Illinois @diwakarshukla
Congratulations to Joseph Clark, undergraduate researcher in our lab and his mentor, Xuenan Mi for publication of their paper on peptide language model, PeptideESM! @MCB_Illinois @diwakarshukla
Congratulations to the newest doctor from our group, Dr. Xuenan Mi! She will join @JNJNews as a research scientist in January! @ChBEIllinois @diwakarshukla
It was our pleasure (@SwansonGroup_UT) to highlight the latest on lasso peptide folding and substrateācyclase tolerance from the Shukla, Burk, and Mitchell teams at @ChemistryUIUC @ChBEIllinois @lassogen: nature.com/articles/s4158ā¦
Congratulations to Prateek Bansal @thepdbguy for winning the ACS PRIDE Merck Graduate Research Award from American Chemical Society! @AmerChemSociety @ChBEIllinois @LASillinois chbe.illinois.edu/news/stories/bā¦
LassoESM: A Tailored Language Model for Enhanced Lasso Peptide Property Prediction ⢠LassoESM is a specialized protein language model (PLM) developed to improve predictions for lasso peptides, which are challenging due to their unique threaded structures and limitedā¦
Thanks to @DrTracyLawson & @leakey77 for leading the ASAP center, and @NSF for funding our research on plant synthetic biology!
Thanks to @DrTracyLawson & @leakey77 for leading the ASAP center, and @NSF for funding our research on plant synthetic biology!
Congratulations to Susanna @SusannaBar2 from Mitchell group @ChemistryUIUC and Song from @ShuklaGroup @ChBEIllinois for their work on understanding how enzymes tie the lasso knot in peptides published in Nature Chemical Biology @nchembio! igb.illinois.edu/article/researā¦
Congratulations to Xuenan Mi for winning the Graduate student excellence award from @ACSCOMP #ACSFall2024! You can read more about it here: shuklagroup.org/events/xuenan-ā¦
Congratulations to Hassan Nadeem, graduate student @BIOENGatIL for receiving the Mavis future faculty fellowship from the college of engineering! @uofigrainge

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