Hugo Snippert @Snippertlab
Cancer biology. Research lab at UMC Utrecht & Oncode Institute. More an explorer than a researcher. snippertlab.org Utrecht, Nederland Joined April 2019-
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1) Excited to share a ms entitled: Integrin-activating Yersinia protein Invasin sustains long-term expansion of primary epithelial cells as 2D #organoid sheets. It describes an alternative to #Matrigel biorxiv.org/cgi/content/sh… A thread:
New publication alert🚨🚨🚨Mechanisms that clear mutations drive field cancerization in mammary tissue is out @Nature nature.com/articles/s4158… Congratulations all for this great team work! 🎉
New publication alert🚨🚨🚨Mechanisms that clear mutations drive field cancerization in mammary tissue is out @Nature nature.com/articles/s4158… Congratulations all for this great team work! 🎉
Big milestone for our group @EMIL_DKFZ @DKFZ: We are thrilled to be among the recipients of an ERC Starting Grant from @ERC_Research #ERCStG! In the #METABAC project, we will explore how gut #bacteria contribute to #colorectal #cancer #metastasis formation. (1/12)
1. Delighted to present work from my time in @AndreaSottoriva's lab, now in @NatureCancer! A big effort also led by @javierfermat and Nick Trahearn. We combined genomics + digital pathology to measure evolution in a prostate cancer (PCa) clinical trial. nature.com/articles/s4301…
How do mismatch repair-deficient (MMRd) cancers trade off the evolutionary costs and benefits of elevated mutation rates? Delighted to share our paper on adaptive mutability in MMRd colorectal cancer (CRC) @NatureGenet nature.com/articles/s4158… Tweetorial 🧵below
Very much love this story to demonstrate that adaptability during tumor evolution can also be achieved at the DNA level by reversible DNA mutations 🔥 @jansen_marnix @UMCU_CMM @oncodeinstitute
Very much love this story to demonstrate that adaptability during tumor evolution can also be achieved at the DNA level by reversible DNA mutations 🔥 @jansen_marnix @UMCU_CMM @oncodeinstitute
Looking forward to present tomorrow morning at #FEBS2024. I’ll discuss our work on real-time single-cell signaling activities in #organoids, drug response and our latest push to advance the technologies involved @UMCU_CMM @oncodeinstitute
Very much enjoyed that we could contribute to the latest discovery of the Brummelkamp team
How does DNA damage cause apoptosis when p53 is mutated? Critical to understand treatment of many tumors. Excited that ‘DNA damage induces p53-independent apoptosis through ribosome stalling’ by Nicolaas Boon and collaborators is out: doi.org/10.1126/scienc…
Check our our latest publication on mouse and human gastruloids in Cell Stem Cell, spearheaded by @Suz_Stelloo with help from @MayteAlVin and many others in our lab and in collaboration with labs of Boudewijn Burgering, Harm Jan Vos, Maarten Altelaar and @SonnenKatharina
Check our our latest publication on mouse and human gastruloids in Cell Stem Cell, spearheaded by @Suz_Stelloo with help from @MayteAlVin and many others in our lab and in collaboration with labs of Boudewijn Burgering, Harm Jan Vos, Maarten Altelaar and @SonnenKatharina
The 2nd edition of OrganoidNL was a great success! We are already looking forward to next year... stay tuned!
We are now live! Register for the 2nd OrganoidNL meeting @_amolf on April 12 🗓️. Exciting talks with opening @HansClevers, keynote Margherita Turco, and talks from @JeroenPasterk @ColindaScheele, Rob Coppes and Quiwei Pan. amolf.nl/organoidnl-sym…
Extremely honoured to receive the ERC Consolidator this year #ERCCoG. Looking forward to the next 5 years of exciting science to unravel the intricacies how tumors become malignant. #CancerPrevention @UMCU_CMM @oncodeinstitute
Extremely honoured to receive the ERC Consolidator this year #ERCCoG. Looking forward to the next 5 years of exciting science to unravel the intricacies how tumors become malignant. #CancerPrevention @UMCU_CMM @oncodeinstitute
Our lastest study "Targeted Perturbation of Signaling-Driven Condensates" is now live on Molecular Cell. We've used small peptides to specificaly disrupt β-catenin condensates, resulting in decreased transcription and inhibition of cancer cell proliferation. 🔬💡 📖 Read more:
Is #cancer drug resistance heritable or plastic? Genetic or non-genetic? How do we tell those apart? We just begun measuring the temporal dynamics of evolving cancers using controllable patient-derived #organoids. We need more experiments+theory! biorxiv.org/content/10.110…
Walking on my way to EMBL cancer genome conference #EMBLCanGen Excited to present our newest work on early-stage colon cancer later today
Are you looking to keep up to date with the rapidly progressing area of cancer genomics? 🤔 Then join us for #EMBLCanGen! ➡️ s.embl.org/can23-01 Submit your abstract by 23 Aug to be a part of this interdisciplinary community of cancer researchers 🥼 #cancerresearch…
We welcome Sjors Middelkamp as our newest postdoc. He got off to a great start this week, being immediately awarded the NWO talent grant ‘Veni’ to continue his research on single-cell genome sequencing that he developed in the @BoxtelLab. @UMCU_CMM @NWOFunding @oncodeinstitute
We welcome Sjors Middelkamp as our newest postdoc. He got off to a great start this week, being immediately awarded the NWO talent grant ‘Veni’ to continue his research on single-cell genome sequencing that he developed in the @BoxtelLab. @UMCU_CMM @NWOFunding @oncodeinstitute
Very proud to see our work on the pan-cancer comparison of the genomic landscapes of primary and metastatic tumor published in this weeks issue of Nature: nature.com/articles/s4158…. @fran_mj88 @arne_van_hoeck @HartwigMedical @UMCU_CMM @oncodeinstitute @VHIO
I am super happy to share the first work of the lab on #gastruloids. All started with @MariettaLHartl that was extremely brave to start a new project on early development. bit.ly/3ocuTqj With @SimonSuppinger they showed mechanisms of gastruloid development
I am super happy to share the first work of the lab on #gastruloids. All started with @MariettaLHartl that was extremely brave to start a new project on early development. bit.ly/3ocuTqj With @SimonSuppinger they showed mechanisms of gastruloid development

Madelon Maurice @MadelonMaurice
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Organoid News @organoidscience
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Keanu Reeves @keanereeveswall
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Leibniz-Institut für... @LeibnizFLI
923 Followers 802 Following Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) Biologische Grundlagen des Alterns/Research for healthy aging https://t.co/saX02AwciX
Emilie de Vet @Emilie_deVet
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Pengfei Yin @Pengfei_Yin_
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Hang Zhou @hang_zhouFLIM
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Anna-Pavlina Haramis @AP_Haramis
360 Followers 339 Following Sr.grant advisor @UMCUtrecht, PhD, biomedical Sciences, #devbio 💜#zebrafish, #metabolism & cool science! https://t.co/FByXZKCX2m @UniLeiden, grant advisor @UvA, @LUMC
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Javier Fernández-Mat... @javierfermat
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sudeepa nandi @NandiSudeepa
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Virginia Brancato @VirginiaBranca3
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ElenaBuetas @ElenaBuetas
273 Followers 811 Following Biomedica. Microbiología, investigación, salud global. La clave esta en querer todo lo que haces y apostar por ello. Disfrutando del momento
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Wren Research Journal... @Wren_Publisher
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Danil Shchukin @dangeshu
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Gene Regulation @generegulation
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1K Followers 468 Following Professor of Molecular Cell Biology @UMCUtrecht, @oncodeinstitute, studying stem and cancer cells, mother of three, sports, volleyball
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3K Followers 3K Following 🦋: @jenspuschhof.bsky.social PI @EMIL_DKFZ. Love collaborative science with enthusiastic people. Fascinated by Cancer Biology, Organoids, Microbes.
Hubrecht Institute @_Hubrecht
5K Followers 114 Following The Hubrecht Institute is no longer active on X. Find us on Bluesky @hubrechtinstitute.bsky.social, Instagram @hubrechtinstitute, LinkedIn or Facebook.
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Tuur Demeester @TuurDemeester
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Thijs Zonneveld @thijszonneveld
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4 Followers 45 Following
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113 Followers 198 Following PhD Student @CNIOStopCancer - La Caixa INPhINIT Retaining @BecariosFLC
Nuria Lopez-Bigas @nlbigas
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Isidro Cortes-Ciriano @isidrolauscher
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237 Followers 128 Following Professor @_amolf. The dynamics of single proteins. But now also the dynamics of organoid development. Not always Sander tweeting.
Yvonne Vercoulen @VercoulenYvonne
245 Followers 170 Following curious, tissue T cell regulation @umcu_cmm, @uya_utrecht, former @ucsf #CyTOF #immunology #cancer #SpatialBiology
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525 Followers 518 Following Genome scientist working at KAIST, Korea, & co-founder of Inocras, USA. Publications available @ https://t.co/uRTB0FRbkl
Francisco Martínez-J... @fran_mj88
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Luke Gromen @LukeGromen
347K Followers 2K Following Founder & President, Forest for the Trees (FFTT). Author of "The Mr. X Interviews, Volumes I & II.” I never solicit via DM's. RT not endorsements.
Epithelium Microenvir... @EMIL_DKFZ
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Institute of Human Bi... @IHB_Research
4K Followers 191 Following Cutting-edge research into #Organoids, #HumanModelSystems & #Microtechnology from #TeamIHB and other experts in the field. A proud part of the @Roche family.
Bas van Steensel lab @bvansteensellab
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Robin H. van der Weid... @RobinWeide
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Guido Barzaghi @BarzaghiGuido
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Claus Jorgensen 🇪�... @claus_jorgensen
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214 Followers 167 Following Endocrine biology, Cancer Biology & Organoid technology. Research lab at ISREC-EPFL
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nic carter @nic__carter
419K Followers 4K Following escaping the permanent underclass | https://t.co/mQ5frnwUMV
solid tumor cancer st... @SUNRiSE_cancer
577 Followers 272 Following The Solid TUmor CaNceR Stem cEll network, (SUNRiSE) aims to bring together scientists with a common interest for the cancer stem cell field in solid tumors.
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Michael Saylor @saylor
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225 Followers 188 Following Assistant Professor at UU | Epigenomics | In vitro embryo models Follow us on Bluesky - @bracciolilab.bsky.social
Moritz Bauer @MoritzBauer_87
294 Followers 272 Following Post-Doc @_Hubrecht @kind_jop lab with a PhD from @CRGenomica @PayerLab. Epigenetics and single-cell technologies … and of course football and post-rock
Dr. Zeynep Hülya Gü... @ZeynepHG
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Mike Nikolaev @mike_nikolaev
407 Followers 301 Following Scientist @Roche @IHB_Research, Alumni @TheLutolfLab, @EPFL Organoids bioengineering & microfabrication 👨🔬🧗🏔⛷
Maria Puschhof @MariaCHeinz
190 Followers 281 Following Computational Scientist at HI-STEM / DKFZ Heterogeneity in cancer | Computational Biomedicine
Leili Rohani @Leili_Rohani
3K Followers 5K Following Scientist @MIT ECR #SynBio #WomenInSTEM trying to design synthetic circuits to save lives! #DiseaseModifyingTherapies. Iran/Germany/Canada/USA @EngBioR
Julian Grünewald @grunewaju
2K Followers 1K Following Assistant Professor @TU_Muenchen. Emmy Noether group leader. CRISPR, cardiology, organoids. previously @JoungLab - views my own.
Joris Hageman @Jorihag
72 Followers 238 Following
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55 Followers 59 Following