Tcipatent @TCIPATENT
The Claimed Intermediate is a Text/Structure Searchable Online Database which covers Process Patents for Named Marketed Pharmaceutical Drugs. tcipatent.com East Sussex, United Kingdom Joined July 2012-
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A high yielding, easily purified key intermediate A - just what's needed! Synthesis 3889 Rivaroxaban is obtained via the synthesis of X-ray defined intermediate A perchlorate salt. (Unichem Laboratories Ltd) #medicinalchemistry #drugprocesspatent #pharmaceuticals #rivaroxaban
#Celecoxib via #flowchemistry Patent Synthesis 4100 Celecoxib is obtained in a flow synthesis with the reaction of prepared intermediates 5 and 6 using flow rates, conditions and solvents as defined #medicinalchemistry #drugprocesschemistry #pharmaceuticals
I'm sure the UK Government will cover any shortfall.....haha!
I'm sure the UK Government will cover any shortfall.....haha!
"Patents are designed to communicate knowledge. Indeed, they can serve as their own form of technical literature." Can and do...…!
"Patents are designed to communicate knowledge. Indeed, they can serve as their own form of technical literature." Can and do...…!
✨SYNTHESIS Editor’s Choice Time!✨If you work in the field of cycloadditions of #tropones, don’t miss this very interesting publication from @vincent_gandon @djpleboeuf and coauthors. Their contribution will be open access for the next 72 h❗ 👉fal.cn/35gpi
Specific for US Patents but general enough for most States!
Specific for US Patents but general enough for most States!
#Formulation Service. bit.ly/2WB0sHI
One of 59 Sitagliptin synthesis patents - @Suvn502 - #Pharma #Patent #Synthesis
Naloxegol - the 4,068th Patent Synthesis added to the Claimed Intermediate Database - Text/Structure Searchable. #Patent #Pharma #Synthesis
Relax and reduce your reaction!
Flow chemistry appearing in patent drug syntheses - #patent, #drugsynthesis, #pharma
Flow chemistry appearing in patent drug syntheses - #patent, #drugsynthesis, #pharma
Novartis team describes optimized, 6 step route to dual kinase inhibitor Dactolisib on 150 kg scale in 51% y. Pd charge in Suzuki coupling reduced to 0.3 mol% by using PPh₃ additive. pubs.acs.org/doi/10.1021/ac…
Noted CN 109796346 (Univ Dalian Tech) ..continuous hydrogenation preparation of aromatic amine through a nitro-compound - a static bed liquid phase catalysis hydrogenation process is utilized and the activity of the catalyst is not lowered after 400-hour continuous running.
✨150 years of the remarkable work of our namegiver: Friedrich Miescher✨The Basler #scientist laid the chemical groundwork for #DNA discovery almost a century before Watson and Crick! 🧬 Read more about his legacy 👉bit.ly/2JOXafj
🤩 Erick Carreira and Moritz Hönig highlighted the great achievement of Jiasu Xu and Viresh Rawal from @UChiChemistry in the enantioselective #totalsynthesis of (–)-Ambiguine in SYNFACTS. 🧐 Well done! 👍 ➡️ Read more: fal.cn/33haf @ETH_en @CarreiraGroup
The storm as it approached #Brighton. #Lightning all along the coast
Very interesting - more process patents include flow synthesis!

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