Tanya Dorff @TDorffOnc
medical oncology, genitourinary cancers Los Angeles, CA Joined September 2017-
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Tanya Dorff retweeted
Thanks to @montypal for hosting. And thanks to @Waltstadler5 for his no nonsense insights. I've been learning from him for many years. It's a pleasure to push the cutting edge of cancer care with colleagues like this.
Thanks to @montypal for hosting. And thanks to @Waltstadler5 for his no nonsense insights. I've been learning from him for many years. It's a pleasure to push the cutting edge of cancer care with colleagues like this.
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Tanya Dorff retweeted
A novel west-African germline founder mutation in HOXB13 (p.X285Kext) increases risk of high-grade prostate cancer but also enhances sensitivity to hormonal therapy. Congrats to PCF-funded Mayuko Kanayama 👏 @neerajaiims @PCFnews @urotoday @EdEsplin nature.com/articles/s4139…
Tanya Dorff retweeted
Finally had a chance to listen to the discussion EVERYONE in the GU community is talking about via @ASCO Virtual Meeting. One of the most thoughtful & eloquent discussions I have ever seen by @jackiebrown_MD @WinshipAtEmory, summarizing excellent presentations from @MichvdHeijden…
Tanya Dorff retweeted
Proud of my mentor @DrMichaelOng presenting impt international #IRONMAN data: 🚹 mCSPC w/ ADT + ARPI 🌀PSA of >= 0.2 at 6-12mo = worse px (mOS 30mo) ➡️consider #TRIPLESWITCH intensification trial now open 🌀PSA<0.2 at 6-12mo = good px ➡️ consider #DEESCALATE trial #ASCO25
Tanya Dorff retweeted
Tanya Dorff retweeted
@TDorffOnc @JasnoorMalhotra Also love the @slusom and @CityofHope_GU connection including @montypal
Tanya Dorff retweeted
Proud of my productive team of #GUOncology @SanRaffaeleMI @MyUniSR occupying the GU Poster Session @ASCO #ASCO25 #PURE01 #SURE01 #NureCombo @ConquerCancerFd @BrigidaMaiorano @vale_tateo @Anto_cigliola @CMercinelli Key takeaways: - SURE01: Luminal subtype & Top1 expression linked…
Impactful work coming from VA data - here, earlier start of docetaxel (<4 months) better than >4 mo. Did inadequate response drive some of the later dosing? Excited to be collab w/ Dr Schoen thru ProfoundVET to improve #prostatecancer care #ASCO25 @JasnoorMalhotra
So great to see friends and colleagues at the poster session for GU including the esteemed and beloved Dr Small! Fantastic posters #ASCO25
Fascinating deep science analyzing molecular underpinnings of sensitivity to 177Lu-PSMA-617 by Jacob Berchuk and Emory colleagues. Why wnt leads to resistance and how to target it? AR activity associated with a/ less response - counterintuitive #ASCO25
Tanya Dorff retweeted
Great poster session this morning with @nsayeghmd highlighting work in #prostatecancer TMB & MSI-H w/ real world IO outcomes @FoundationATCG! Truly a star resident @utswcancer @UTSWInternalMed co-mentored by me & @neerajaiims. Look out for his fellowship apps this fall! #ASCO25
Beautiful lakeside run this morning - why have I never done this before?! #ASCO25 Chicago, you are one beautiful city!
Tanya Dorff retweeted
Kudos @montypal on such a fantastic presentation and setting the stage for biomarker development in Kidney cancer! @neerajaiims @brian_rini @tompowles1 @Uromigos @DrChoueiri @TiansterZhang
Kudos @montypal on such a fantastic presentation and setting the stage for biomarker development in Kidney cancer! @neerajaiims @brian_rini @tompowles1 @Uromigos @DrChoueiri @TiansterZhang
Tanya Dorff retweeted
Thank you @VivekNarayanMD, of @PennCancer, for sharing the 5-year data with us on the HIF-2α inhibitor belzutifan in VHL disease–associated neoplasms. We can't believe it's been 4 years since its @US_FDA approval. Check out hubs.li/Q03q4Lj10 for his insights @ASCO #ASCO25
Tanya Dorff retweeted
🗣️Prostate Rapid Oral Abstract #ASCO25 👉Abst5017: Dr #CapucineBaldini presenting #Pasritamig in mCRPC 🔑 KEY TAKE AWAYS - #Pasritamig well tolerated (<10% G1 CRS @ RP2D) with promising antitumor activity. - Proof of concept for #KLK2 as a target amenable to T-cell…
Tanya Dorff retweeted
Fantastic activity of first in class B7H3 ADC DB1311 for patients w metastatic castration resistant #prostatecancer - we had trial open w #KevinCourtney @utswcancer & had patients benefit! @ASCO #ASCO25 @OncoAlert
Fantastic activity of first in class B7H3 ADC DB1311 for patients w metastatic castration resistant #prostatecancer - we had trial open w #KevinCourtney @utswcancer & had patients benefit! @ASCO #ASCO25 @OncoAlert https://t.co/dAYLXJ9ec7
Exceptionally clear, thoughtful discussion by @jacquelinebrown suggesting there may still be a role for SG in the future with appropriately designed trials including mandatory gcsf #ASCO25
Excellent presentation of EV +P response analysis by @shilpaonc #ASCO25 finds most CR durable and safety maintained despite median 13 cycles (up to 50!) EV due to dose modifications
Tanya Dorff retweeted
Impressive data for 9MW2821 (Nectin4/MMAE ADC) & Toripalimab (n=40) RR =80% (EVP & DVP 73%/75% in phase 2). TRAEs >G3 neutrophil ⬇️ (8%), rash (5%), ALT⬆️ (5%). lrss skin tox? Also high responses in Nectin4 low. This will be in R3 very soon in china I suspect. #ASCO25
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