The Thalion Initiative is a global researcher driven initiative focused on the fundamental biology of aging.
US Head Office. Visit @TheThalionInit in Canadathalion.global Boston, MAJoined December 2024
Sequencing the bowhead whale genome was deemed too risky by government and traditional funding bodies.
In fact, our project was only possible thanks to smaller charities and donors.
It's a hurdle in science that most funders are risk-adverse. We need bolder research!
Sequencing the bowhead whale genome was deemed too risky by government and traditional funding bodies.
In fact, our project was only possible thanks to smaller charities and donors.
It's a hurdle in science that most funders are risk-adverse. We need bolder research!
Thanks to Vicky Kelberer for her insights this week and helping us work with Donor Advised Funds, like @VC_Giving . Appreciate the support of @CandidDotOrg in making connections and navigating the increasing complexity of impactful philanthropy.
Join us for the second edition of this Physics in Aging Biology workshop at @ARDD_Meeting.
Last year the room was packed and the energy was high!
Glad to have npj Aging supporting!
Join us for the second edition of this Physics in Aging Biology workshop at @ARDD_Meeting.
Last year the room was packed and the energy was high!
Glad to have npj Aging supporting!
To wrap up our GLP-1RA saga this week, let's zoom in on one of the wildest origins stories in modern medicine. Take a look at the Gila monster (Heloderma suspectum), a chunky, slow-moving lizard from the Southwestern U.S. and Mexico deserts. Believe it or not, one of the first…
Our thanks to @FidelityChrtbl for making working with Donor Advised Funds (DAFs ) easy, flexible and smooth. A great team and resources for both patrons and Thalion as we pursue our mission.
New preprint with our list of 100 open problems in ageing science.
Our curated list captures both long-standing fundamental questions and emerging research frontiers.
A massive team effort by >30 researchers from many disciplines in biogerontology.
arxiv.org/abs/2507.18602
Great overview of the various branches of thoughts on aging.
However, I always find the word “theory” in this context too strong and misused as it signals more robust understanding than there actually is.
Most of these thoughts are hypotheses, not theories.
Great overview of the various branches of thoughts on aging.
However, I always find the word “theory” in this context too strong and misused as it signals more robust understanding than there actually is.
Most of these thoughts are hypotheses, not theories.
New preprint (from a stellar team) on how PARP1 variants regulate ovarian reserve and menopause timing by affecting early germ cell fate, with mechanistic insight and supported with human genetics data. Thread >>
medrxiv.org/content/medrxi…
Lifestyle interventions, supplements and the current state of non-evidence based longevity medicine distract the Geroscience field from developing meaningful rejuvenation therapies by diverting resources to low impact science and competing for the minds of top scientist.
We’ve built structures that reward predictability and incremental improvements over risk (risk that might lead to real breakthroughs, new paradigms, or entirely new fields), and publishability over curiosity.
These issues resonate with @TTIScience
We believe many of biology’s…
@JTLonsdale Step 5: build a solid and strong pipeline on fundamental biology for pre-clinical moonshot research.
Otherwise the clinical pipeline will eventually dry up.
At @TTIScience we are doing this for aging biology.
Looking forward to the Life Summit in Berlin and spread some of the concepts and thinking behind The Thalion Initiative - an effort to rethink the fundamentals of aging biology.
Being German myself I’m glad that this event brings the German and international longevity community…
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