Account of the Chromatin, cancer and the ubiquitin system lab, based in the CBM. Focus on DNA replication dynamics, ubiquitin, SUMO and cancer. CBM, CSIC-UAM - MadridJoined March 2024
Another exciting research article from a member of the #RepliFate network!
The @altmeyerlab identified the CNOT1-CCR4-NOT complex as a multi-level suppressor of the 53BP1-p53-p21 signaling axis.
Check out their findings here: doi.org/10.1016/j.celr…
We are looking for a candidate to apply to a #MSCA Postdoctoral Fellowship in our lab in the @CBM_CSIC_UAM, working on the connections between DNA replication dynamics, replication stress and genomic instability in cáncer. Contact us if you are interested and please retweet.
Just published!
Lecona & Méndez #RepliFate labs show that VCP/p97 removes Pol α/primase from chromatin to avoid excess ATR activation during normal #DNAreplication
VCP/p97 = checkpoint gatekeeper!
Read the full article: doi.org/10.1038/s41467…
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[email protected]
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#Sinciencianohayfuturo
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#SinCienciaNoHayFuturo
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#Sinciencianohayfuturo
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[email protected]
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128 Followers 78 FollowingWorking at the interface of DNA replication, transcription, chromatin and nuclear organization. Passionate about genome functionality. María Gómez Lab