VN2M team - Durand lab @VN2Mteam
(V)irulence (N)ano(M)acromolecular (M)achinosome Laboratoire d'Ingénierie des Systèmes Macromoléculaires (LISM) CNRS UMR7255 INSERM ericdurand3.wixsite.com/vn2m Marseille (FRANCE) Joined November 2012-
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Ready… Set… Start ! 🏁 CENTURI is launching the 2024 edition of the PhD call! 📣 8 open PhD positions available! ⏰Applications open until February 15 🎙️Interviews via zoom on April 10-11 Check all our projects here! centuri-livingsystems.org/recruitment/ #interdisciplinarity #call #phd #job
3/4 Amazing collaboration with BD Ross lab (Dartmouth College US), @RiccardoPellari (ENS Lyon), @epcrocha (Institut Pasteur Paris), Stengel lab (University of Konstanz) and the great support of @lcb_officiel), LISM, CNRSbiologie) and @Inserm
3/4 Amazing collaboration with BD Ross lab (Dartmouth College US), @RiccardoPellari (ENS Lyon), @epcrocha (Institut Pasteur Paris), Stengel lab (University of Konstanz) and the great support of @lcb_officiel), LISM, CNRSbiologie) and I@Inserm
2/4 We are the first to demonstrate its assembly and molecular intimacy. Stay tuned for future fascinating stories….
1/4 Delighted to announce the publication of the first PhD article of Thibault Bongiovanni from the VN2M team at LCB (@VN2Mteam). We discovered the unique membrane complex in the type VI secretion (T6SS) system of Bacteroidota…
Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae cell.com/cell/pdf/S0092…
📢Publication @Nature : Pour la 1re fois, des chercheurs @institut_curie @CNRS @Inserm dévoilent une chaîne de réactions impliquant le cuivre, qui active inflammation et progression tumorale. Ils ont également inventé une molécule capable de l’atténuer. ➡ curie.fr/actualite/publ…
Turning high-throughput structural biology into predictive inhibitor design | Proceedings of the National Academy of Sciences pnas.org/doi/10.1073/pn…
See below for the work I'll be sharing at drugdiscoverychemistry.com/fragment-based…. I hope you can attend -- here is also a discount code the organizers shared with me to input when you register: SPK150 #drugdiscoverychemistry #medicinalchemistry
Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility science.org/doi/10.1126/sc…
We are featured in a nice article in @DrugDiscovNews ! #Odilorhabdin #NOSO502 drugdiscoverynews.com/worm-associate…
Very pleased to be featured in @DrugDiscovNews ! Nice article by @sci_steph on our novel antibiotic class of the #Odilorhabdins and the microbial biodiversity that naturally produces them: #Photorhabdus and #Xenorhabdus .
Very pleased to be featured in @DrugDiscovNews ! Nice article by @sci_steph on our novel antibiotic class of the #Odilorhabdins and the microbial biodiversity that naturally produces them: #Photorhabdus and #Xenorhabdus .
Check our new paper on the chemical optimization & initial evaluation in cellular & animal models of @antabio's #Pseudomonas #aeruginosa #LasB inhibitors. An international collaboration based on a work initially funded by @wellcometrust & @CARB_X pubs.acs.org/doi/10.1021/ac…
Very pleased to have contributed to this exciting story published @ScienceAdvances. A new synthetic approach for hairpin peptide design for the discovery of new therapeutics against bacterial pathogens #AMR. Read the paper here: science.org/doi/10.1126/sc…
The LCB is happy to welcome a 14th team. This is Eric Durand’s team : “#Virulence Nano-Macromolecular Machinosome” (VN2M). The team aims to Identify, to Understand, to Block and to Hijack bacterial #nanomachines that challenge #humanhealth. #microbiology lcb.cnrs.fr/team/durand/
Starting the new year right with our story being published in @FrontMicrobiol today! Give our #T6SS #Pseudomonas effector diversity in clinical isolates study a read! #microbiology #phdlife @luke_allsopp, @janedaviescf @Mic_Ro_ frontiersin.org/articles/10.33…
H3-T6SS of Pseudomonas aeruginosa PA14 contributes to environmental adaptation via secretion of a biofilm-promoting effector link.springer.com/article/10.100…
Fighting antibiotic resistance—strategies and (pre)clinical developments to find new antibacterials embopress.org/doi/full/10.15…
Cascales Lab @CascalesLab
5K Followers 3K Following How to specifically select a protein from one side of the membrane and to transport it on the other side ? That's what we will love to understand. #T6SS #T9SSDukas Jurenas 🇺�.. @DukasJu
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Ready… Set… Start ! 🏁 CENTURI is launching the 2024 edition of the PhD call! 📣 8 open PhD positions available! ⏰Applications open until February 15 🎙️Interviews via zoom on April 10-11 Check all our projects here! centuri-livingsystems.org/recruitment/ #interdisciplinarity #call #phd #job
Thanks, Ben et al (@VN2Mteam @RiccardoPellari Youn le Cras). Hopefully, the 1st of many coll. These key components of the membrane complex of T6SS in Bacteroidota have intriguing distributions and genetic organisations. Next question: how did this come about?
Very happy to share the culmination of a very fun 6+ year (!) collaboration with @VN2Mteam investigating the T6SS membrane complex of Bacteroidota. Thanks to all co-authors @epcrocha nature.com/articles/s4146…
Finally online: architecture and composition B. Fragilis T6SS membrane complex. A great work lead by E. Durand and T. Bongiovanni. With E. Rocha, B. Ross, F. Stengel. @CNRSbiologie @Lyon_LBMC @MMSB_Lyon @institutpasteur @lcb_officiel @UniKonstanz tinyurl.com/45evxc46
Very happy to share the culmination of a very fun 6+ year (!) collaboration with @VN2Mteam investigating the T6SS membrane complex of Bacteroidota. Thanks to all co-authors @epcrocha nature.com/articles/s4146…
How do #cells and #genes build #embryos? Is our identity in our genomes or is it created by our cells? From the birth of the cell to how we use #StemCells to answer these questions. The beginning of an argument shorturl.at/agJK7 @NextBigIdeaClub #NotInTheGenes #cellsRus
Just came back from my CCC Ultra Trail. live.utmb.world/utmb/2023/runn… Could not make the cut off time at checkpoint 4 (km 54) so was stopped by the race direction. Disppointed for not completing the race but beautiful scenray and motivated to try it one more time.
Happy to share the last paper of pour lab on the resistome transcriptimics in urban and hospital wastewaters. Wonderful work @ElenaBuelow. sciencedirect.com/science/articl… #AMR #wastewater #surveillance @unilim @Inserm @CHULimoges 🙏programme @EU_Commission sklodowska-curie programme
Back for a short visit at Imperial. Please to see that I have left some legacy there with the Queen tower redesigned as a T6SS device.
Wrapping up the week with @Xavier_Morelli and his inspiring words: “Creating a positive atmosphere, filled with hope.” #HopefulFuture #WeekendVibes #CRCM50 #50portraitsCRCM50 #DiversityInResearch #FightingCancer
📢Publication @Nature : Pour la 1re fois, des chercheurs @institut_curie @CNRS @Inserm dévoilent une chaîne de réactions impliquant le cuivre, qui active inflammation et progression tumorale. Ils ont également inventé une molécule capable de l’atténuer. ➡ curie.fr/actualite/publ…
Très honoré et très fier de notre sélection dans la toute 1ère promotion French Tech #Health20! Elle récompense notre engagement dans l'innovation thérapeutique anti-infectieuse, en particulier dans la lutte contre l'antibiorésistance. Merci à toute l'équipe et à nos partenaires!
Nosopharm est lauréate de la 1ère promotion du French Tech #Health20 ! 🔬Le programme d'accompagnement de @LaFrenchTech et l’AIS dédié aux #startup prometteuses de la #healthtech Pour en savoir plus sur le programme 👉 lafrenchtech.com/fr/la-france-a…
30 ans de carrière dans le service! @CHULimoges #bacteriologie-virologie-hygiene. #BK #P3. Merci pour ces années auprès de nous, ta fidélité et ton engagement et ton écoute au quotidien. Tous tes collègues étaient présents pour fêter avec toi ton départ.
Such beautiful work - there have been so many exciting developments in the field of bacterial nanomachines over the last decade! #T4SS
biorxiv.org/content/10.110… I started this project ~6 years ago, collected ~ 3000 tomograms of WT and mutant Legionella strains, identified a mutant that stabilised the Legionella T4SS, and collected ~500 more tomograms of this strain.
Turning high-throughput structural biology into predictive inhibitor design | Proceedings of the National Academy of Sciences pnas.org/doi/10.1073/pn…
J’ai eu l’honneur, en tant que Président du Comité Scientifique du @CanceropolePACA de présider ce soir la cérémonie de remise des prix du 14ème appel à projets pour l’innovation et la santé en présence de Charles Ange GINÉSY et d’ @ECiotti et de remet…lnkd.in/eT4i7kTm
See below for the work I'll be sharing at drugdiscoverychemistry.com/fragment-based…. I hope you can attend -- here is also a discount code the organizers shared with me to input when you register: SPK150 #drugdiscoverychemistry #medicinalchemistry
Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility science.org/doi/10.1126/sc…
Do bacteria target mitochondria using the same weapons as they do to compete each other? YES. Check our work on how Klebsiella T6SS targets the mitochondria @NatureComms. We also shed new light into mitochondria located innate receptor NLRX1. nature.com/articles/s4146…