Vahidi Lab@UofGuelph 🇨🇦 @VahidiLab
Assistant Professor @uofg | Biochemist | Structural Biologist | Mass spectrometry | NMR spectroscopy vahidilab.ca Guelph, ON, Canada Joined February 2020-
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MCB @ U of Guelph is hiring (again)! 🎉 Tenure-track Assistant Professor in Biochemistry Part of our strategic cluster hire. Apply now 👉 careers.uoguelph.ca/job/Guelph-Ass… #Biochemistry #FacultyJobs #AcademicTwitter #MolBio
Out in @pnas today Showcasing the power of NMR! NMR and enzyme kinetics show USP7 enzyme transiently sampling a low-populated active state, and its disease-causing variant enhancing these dynamics pnas.org/doi/10.1073/pn… Stellar work by students Gabi Valles and Emilie Korchak
Congrats to Monica Goncalves and Madison Turner for winning the 2025 Dr. Donald R. Phillips Molecular & Cellular Biology Scholarship! The award recognizes research excellence, academic achievement, and meaningful contributions to MCB. Congrats to their supervisor, @VahidiLab!
Don’t miss the Ann Oaks Lecture in Biological Sciences, with Dr. Lewis Kay, professor of molecular genetics, biochemistry & chemistry @UofT 🗓️May 28 at 2 p.m. 📍ALEX 100 More info: uoguelph.ca/cbs/events/202…
Excited to share our new publication with @VahidiLab! We reveal how human mitochondrial ClpP is allosterically activated—even by inhibitors—unlocking new strategies to target ClpP in AML. pnas.org/doi/10.1073/pn…
New findings from #UofG researchers could help unlock better treatments for leukaemia and tuberculosis. The studies focus on specialized enzymes that destroy damaged proteins and reveal how these enzymes can be switched on or off. Learn more: uoguel.ph/fxwpf
A fantastic lab and an excellent PI!
Credit to outstanding trainees and collaborators, including @NatalieZeytuni and @UdayAdwaith
Credit to outstanding trainees and collaborators, including @NatalieZeytuni and @UdayAdwaith
New #UofG research may unlock better treatments for leukemia and tuberculosis, which affect millions worldwide. “If we can trap these enzymes, there is a chance we can make some very potent therapeutics," says Dr. Siavash Vahidi. @UofGCBS Read more: news.uoguelph.ca/2025/04/protei…
Thrilled to share our new paper revealing an auto-inhibited state of the M. tuberculosis 20S proteasome—highlighting allosteric sites with therapeutic potential. A fantastic collaboration with the @VahidiLab! 🔗 nature.com/articles/s4146… #cryoEM #TBresearch #StructuralBiology
Mechanism of allosteric activation in human mitochondrial ClpP protease | PNAS pnas.org/doi/10.1073/pn…
Bit of a late post, but I had the incredible opportunity to attend and present my work at the Biophysical Society Annual Meeting this year! It was my first #BPS and also my first conference outside Canada. I got to learn from so many inspiring biophysicists doing amazing science!
Professor Lewis Kay @LEK_Lab @UofT is honoured with the 2025 Alexander Hollaender Award in Biophysics awarded by the U.S. National Academy of Sciences @theNASciences for outstanding contributions to the field of biophysics utoronto.ca/celebrates/lew… #NMRnews #NMRchat #NMR 🧲
#OnTheBeamlines: Evidence links gum disease to heart diseases, cancer and Alzheimer's. A @mcgillu team has used our CLS to study how gum disease bacteria spread in the body to help develop new antimicrobial drugs one day. 🔬 bit.ly/3VwOaAB #synchrotron #science #health
Neuroscientists at #UofG are researching key enzymes in patients with Huntington’s disease, aiming to lay the groundwork for therapeutic treatment for patients with Huntington’s and other neurodegenerative disorders. @UofGCBS @UofG_MCB Read more: news.uoguelph.ca/2024/10/neuros…
We must rapidly reverse our discovery research funding death spiral. Our future health and wealth depends on a well funded robust scientific research enterprise policyoptions.irpp.org/magazines/octo…. @bradwouters @CIHR_IRSC @NSERC_CRSNG @picardonhealth @cafreeland @FP_Champagne @ISGSenate
I am looking for a highly talented postdoc to join my lab to study ATP-dependent AAA machines using structural biology, biochemistry, and mass spectrometry. Please apply through the following link: bit.ly/4haSZID For more information, visit: sites.wustl.edu/ghanbarpour/
@VahidiLab @chimerix many congratulations, Siavash and the team! Looking forward to reading the preprint.

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