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    Murphy Lab @_Murphy_Lab

    2 years ago

    🎉 Our latest preprint is now online 👉 biorxiv.org/content/10.110… Congrats to @RalfSteinhilper who determined #cryoEM structures of the ferredoxin 2-bound core iron-sulfur cluster assembly complex under reducing and turnover conditions at 2 Å resolution. More below! 👇 🧵 1/8

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    Murphy Lab @_Murphy_Lab

    2 years ago

    #Mitochondria are known as the ‘powerhouses’ of the cell. But an even more widely conserved function is the biosynthesis of inorganic protein cofactors called iron-sulfur #FeS clusters, which are built de novo from free cysteine and iron by the core ISC complex. 🧵 2/8

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