Sabarinath Subramanian @_SabarinathPS
Postdoc @GundryLab, UNMC #Glycobiology, #massspectrometry Omaha, Nebraska Joined October 2019-
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#glycotime Glycans do wonders in the lipoprotein world! Please check-out our recent review on apolipoprotein glycosylation published in iScience. @Gundrylab @UNMCCOM The known unknowns of apolipoprotein glycosylation in health and disease cell.com/iscience/fullt…
for some sugar high! Check out our recent work on the O-glycome of planaria published in Glycobiology @hurryram , @DPalakodeti , @VairavanL @DBT_inStem, @PurdueBiolSci academic.oup.com/glycob/advance…
1487 views and 320 downloads so far... I hope somebody is testing if methylcobalamin can inhibit Sars-CoV-2 replication. preprints.org/manuscript/202…
Work from our group featured as the cover article in @FEBS_Letters. Image: @Vinay_k_Dubey Art by @srikarkrishna_g. Paper Link: doi.org/10.1002/1873-3… @hurryram @_SabarinathPS @inStem_India @DPalakodeti Thanks to @IndiaDST @DBTIndia for funding.
Phosphatases are known to be phosphorylated. But did you know that OGA can be O-GlcNAc -modified by OGT? It is extremely challenging to study this due to the rapid hydrolysis. Genetic recoding with a stable S-GlcNAc allowed us to circumvent this problem! nature.com/articles/s4159…
Delighted to share my 1st lead-author publication! We repurposed the fortuitous cysteine S-GlcNAc transferase activity of O-GlcNAc transferase to study the roles of site-specific protein O-GlcNAcylation in cells using #CRISPR! #glycotime! (1) nature.com/articles/s4159…
Olona Limacodidae. The gummy bear hedgehog of nature.
I am somewhat late in sharing this paper, but have a look. Vey interesting concept of presenting glycosylation using the language of epigenetics.
I am somewhat late in sharing this paper, but have a look. Vey interesting concept of presenting glycosylation using the language of epigenetics.
Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma. - PubMed - NCBI ncbi.nlm.nih.gov/pubmed/31675502
Mannose-6-phosphate trafficking is textbook biochemistry, but there's still so much to learn. Amazing structural biology insights into Man-6-P Receptors from Nancy Dahms, @SFGlycobiology 2019 Rosalind Kornfeld Award winner.
Galactose-based metabolic reporter ..
It is yellow, the two proteins must interact! A few thoughts about #colocalization in #fluorescence #microscopy. wp.me/p6m2Op-jF
Very happy to share this review on "Oncometabolites in renal cancer" nature.com/articles/s4158… @NatRevNeph Excellent work from Cissy Yong, the real driver of the review, and @grantissimus We hope you will find it interesting and comprehensive.
#Serotonin is essential for eye regeneration in #planaria →febs.onlinelibrary.wiley.com/doi/10.1002/18… #stemcells #celldifferentiation #progenitorcells #tissueregeneration #stemness #metabolomics #regenerativebiology
A 2017 impactful article for #SfN19 @Neurosci2019 attendees to read as they start settling into their Chicago hotel rooms 'Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation' acspubs.co/cLX150wNZ6K

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