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Thomas Thumberger @_ThomThum_

Developmental biologist @COSHeidelberg @WittbrodtLab chalk-talker, CRISPRer, Baseeditor & glycosylation & CDG modeler. crispr.cos.uni-heidelberg.de Heidelberg Joined October 2013
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Thomas Thumberger @_ThomThum_

5 months ago

Register quickly and swim by! #medaka #meeting

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WittbrodtLab @WittbrodtLab

5 months ago

Register quickly and swim by! #medaka #meeting

Thomas Thumberger retweeted
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WittbrodtLab @WittbrodtLab

a year ago

New high-throughput optomotor response (OMR) assay for medaka fish larvae reveals strain-specific visual function differences & training effects. Our open-source setup enables studies on visual acuity, color sensitivity & more #NeuroBiology #FishResearch 🐠journals.plos.org/plosone/articl…

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GfE @GfEeV

a year ago

That's it: #GfE2024 is over. Thanks everyone for the science, amazing talks, chairing, buzzing poster sessions, short & long discussions, organizers in the back & front - simply thanks for all your contributions! See you all latest at #GfE2026 for updates & new routes of #DevBio

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Thomas Thumberger @_ThomThum_

a year ago

and furthered by comparison with other regenerating and non-regenerating fish like the surface and cave phenotypes of #astyanax. impressive talk at #GfE2024!

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GfE @GfEeV

a year ago

and furthered by comparison with other regenerating and non-regenerating fish like the surface and cave phenotypes of #astyanax. impressive talk at #GfE2024!

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Thomas Thumberger @_ThomThum_

a year ago

very nice talk from @Adelmann_L on #platynereis. She makes use of #scTranscriptomics over time during the course of regeneration and finds stem cell hotspots in different clusters 💪 #GfE2024

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GfE @GfEeV

a year ago

very nice talk from @Adelmann_L on #platynereis. She makes use of #scTranscriptomics over time during the course of regeneration and finds stem cell hotspots in different clusters 💪 #GfE2024

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Thomas Thumberger @_ThomThum_

a year ago

If you desperately need to explain the problem of in vitro recombination in #PCR fooling many to believe #CRISPR/#HDR events went smooth, use the remainder space on your poster 😂 read up here for fish elifesciences.org/articles/39468 & here for the mouse academic.oup.com/nar/article/51… #GfE2024

Thomas Thumberger retweeted
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AQMHD @AquaticModels

2 years ago

Announcing the fantastic keynote speakers for the 11th AQMHD Conference: Leonard Zon, Jochen Wittbrodt, and Duygu Ozpolat. Registration and more information can be found here: aqmhd.xiphophorus.txst.edu.

Thomas Thumberger retweeted
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GfE @GfEeV

2 years ago

Dolf Weijers (@dolfweijers) opens the third day of #GfE2024, emphasizing two important things: 1) #DevBio is not dead but thriving in various directions obvious from the GfE/DSDB joint meeting. 2) the importance of #DevBio societies - join your local clubs!

Thomas Thumberger retweeted
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the Node @the_Node

2 years ago

Are you a #DevBio researcher in Germany? Have you joined @GfEeV as a member yet?👇

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GfE @GfEeV

2 years ago

Are you a #DevBio researcher in Germany? Have you joined @GfEeV as a member yet?👇

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Thomas Thumberger @_ThomThum_

2 years ago

Great talk by Christof about one of the hallmarks of #DevBio. Brings back memories of the good time I spent on the organizer during my PhD dissecting its downstream left-right organizing activity. #xenopus #cilia #LROrganizer

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GfE @GfEeV

2 years ago

Great talk by Christof about one of the hallmarks of #DevBio. Brings back memories of the good time I spent on the organizer during my PhD dissecting its downstream left-right organizing activity. #xenopus #cilia #LROrganizer

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Thomas Thumberger @_ThomThum_

2 years ago

#GfE2024 last talk of the Stem cell session. Jochen talking about our SNP validation screen on heart-beat Gene-by-Environment alleles - CRISPR/BaseEditing SNP-fipping validated by CRISPR & ACEofBASEs editing aceofbases.cos.uni-heidelberg.de

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GfE @GfEeV

2 years ago

#GfE2024 last talk of the Stem cell session. Jochen talking about our SNP validation screen on heart-beat Gene-by-Environment alleles - CRISPR/BaseEditing SNP-fipping validated by CRISPR & ACEofBASEs editing aceofbases.cos.uni-heidelberg.de

Thomas Thumberger retweeted
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GfE @GfEeV

2 years ago

Jochen Wittbrodt (@WittbrodtLab) "genetics of individuality" population genetics based on our inner fish. How SNPs influence traits like the 🫀 heart beat in a Gene-by-Environment dependency (GxE) #medaka #GWAS

Thomas Thumberger retweeted
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Sergio Perez Acebron @Acebron

2 years ago

Open PhD position in Heidelberg. Please RT! Do you want to identify the molecular mechanisms regulating genomic and chromosomal mosaicism in the developing brain? We seek a motivated doctoral researcher @COSHeidelberg @UniHeidelberg. Apply by 15 April here euraxess.ec.europa.eu/jobs/87408

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Thomas Thumberger @_ThomThum_

3 years ago

CRISPR-Fortschritte - Schnitt für Schnitt zu neuen Möglichkeiten: unser Review über sukzessive, kleine Fortschritte, die gezieltes Genomeditieren mittels CRISPR & BaseEditoren effizienter gemacht haben link.springer.com/article/10.100… ✂️ mit @kaisa_pakari & @WittbrodtLab im @Spektrum_BIO

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Thomas Thumberger @_ThomThum_

3 years ago

I guess this meeting is focusing on zebrafish fin mutants 😉

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MidAtlanticRegionZebrafish-ers @MARZmeeting

3 years ago

I guess this meeting is focusing on zebrafish fin mutants 😉

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Thomas Thumberger @_ThomThum_

3 years ago

ahhh, bench air! Dear #miniprep, how I missed you! You routine chance for self-optimization. You simple process that grants room to think while doing, that makes automated movements happen thanks to imprinted memory in my Medulla spinalis. Even after years of abstinence. Thank U!

Thomas Thumberger retweeted
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Uni Heidelberg @UniHeidelberg

3 years ago

Verfahren der Genom-Editierung optimiert: Heidelberger Wissenschaftlern gelingt es, die Effizienz von CRISPR/Cas9 sowie verwandten Methoden zu steigern und bislang unerreichbare DNA-Sequenzen zu modifizieren uni-heidelberg.de/de/newsroom/ve…

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Thomas Thumberger @_ThomThum_

3 years ago

Just published @Dev_journal, Kaisa (@kaisa_pakari) presents our "inception" approach to target previously inaccessible nucleotides with base-editing at the 1st Heidelberg #CRISPR mini symposium @MKolleg today - link to paper: journals.biologists.com/dev/article/15…

Thomas Thumberger retweeted
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WittbrodtLab @WittbrodtLab

3 years ago

Here it is: our #inception paper @Dev_journal „De novo PAM generation to reach initially inaccessible target sites for base editing“ by @kaisa_pakari & @_ThomThum_ We use 2 guides & 2 editors to edit distant nucleotides with NGG base-editors journals.biologists.com/dev/article-ab… #medaka #DNA

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