haniel.araujo @_hanielaraujo
Assistant Professor - Thoracic Medical Oncology - MD Anderson Cancer Center Houston, TX Joined May 2020-
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Dr. Haniel Araujo(@_hanielaraujo )@MDAndersonNews outlined phase 1 results for zoldonrasib, an oral covalent RAS(ON)-G12D inhibitor: ORR 61 % in KRAS G12D NSCLC at the 1200 mg QD RP2D; median time-to-response 1.4 mo and mostly grade 1 AEs. RMC-LUNG-101 expansion is now enrolling.
Excited to share our new study @Nature. Very grateful for the support of our collaborators, pharma and biotech partners and members of the Skoulidis and Heymach labs. Special thanks to star fellow @_hanielaraujo and @minhtruongdo. Thankful to our patients. @MDAndersonNews
@HCCvPDAC Lastly, @_hanielaraujo, @XimoPechuan, Teng Zhou, @FSkoulidis, et al show in NSCLC the RAS(ON) multiselective inhibitor RMC-7977 is active in KRASG12C-mut models resistant to G12C inhibitors, but a mucinous txtn state supports drug tolerance doi.org/10.1158/2159-8… @MDAndersonNews

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