Jessica Matthias @_jessematthias
Senior MINFLUX Application Scientist @abberior | PhD @StefanHellLabs Bethesda, MD, USA Joined March 2023-
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(1/13) Thread on @mazzocca_matteo @DomenicNarducci @SGrosseHolz @_jessematthias new preprint Q: how does chromatin move? Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide some answers biorxiv.org/content/10.110…
Check out our new preprint from @mazzocca_matteo @DomenicNarducci @SGrosseHolz @_jessematthias profiling chromatin dynamics across 7 orders of magnitude in time using MINFLUX providing insights into first passage times for distal genomic interactions: biorxiv.org/content/10.110…
Check out our new preprint from @mazzocca_matteo @DomenicNarducci @SGrosseHolz @_jessematthias profiling chromatin dynamics across 7 orders of magnitude in time using MINFLUX providing insights into first passage times for distal genomic interactions: biorxiv.org/content/10.110…
Yes, as expected, Kinesin-3 KIF1A predominantly adopts a two-heads-bound state, both at saturating and limiting ATP concentrations. This contrasts with Kinesin-1 KIF5B and provides a mechanistic explanation for KIF1A's superprocessivity. Check out the details in our latest…
#MINFLUX detects two arrangements of a protein subunit dimer by directly resolving fluorescent markers at and below FRET-range distances. MINFLUX #imaging has gone inTRA-molecular! Learn more at science.org/doi/10.1126/sc… and mpinat.mpg.de/4816514/pr_2419 @MPinat @mpi_mr_hd #Optics #
Published in @ScienceMagazine: "Direct optical measurement of intramolecular distances with angstrom precision" (Sahl et al.) science.org/doi/10.1126/sc… @mpi_nat @mpi_mr_hd #Optics #Imaging #Microscopy #MINFLUX #Fluorescence
A team led by Steffen Sahl & @Stefan_W_Hell @mpi_nat and @mpi_mr_hd has succeeded in measuring distances within biomolecules using the #MINFLUX microscopy method, down to 1 nanometer and with Ångström precision. Read more in our press release: mpinat.mpg.de/4816514/pr_2419
🥳Huge congrats to our very own Katarina Chapman and Philip Matthias on being selected to join the 73rd Lindau Nobel Laureate Meeting @lindaunobel as Young Scientists! @StefanHellLabs @maxplanckpress
In our newest work from @StefanHellLabs at @mpi_mr_hd M. Remmel and @_jessematthias showcase PaX dyes for quantitative and live-cell @MInflux nanoscopy. We also report a new dye, PaX595, for dual color 561 MINFLUX imaging based on spectral classification. doi.org/10.1002/smtd.2…
MINFLUX is hot on the heels of kinesin in cells biorxiv.org/content/10.110…
The @StefanHellLabs family at #SMLMS2023 — 🍩's past and present united! @AndImaging, R. Gerasimaite, @IlariaTesta4 @LOstersehlt @VicidominiLab @BalzarottiFran, I.Jansen, @RLincolnChemist @ElisaDEste, J.O.Wirth, S.J.Sahl, @wmarkbates @bewersdorflab Missing:@JGDanzl & @SSchnorren
Intra-molecular resolution. With focused visible light: biorxiv.org/content/10.110… @mpi_nat @mpi_mr_hd #MINFLUX #FRET #Fluorescence #Superresolution #Microscopy
Fretting over #FRET distances 😥? #MINFLUX can be the answer 😃💡! See our paper by S. Sahl et al: biorxiv.org/content/10.110…
Powerful microscope captures motor proteins in unprecedented detail nature.com/articles/d4158…
“But it (#MINFLUX) was also well suited, for the first time, for tracking single #fluorophores with simultaneous #nanometer and millisecond precision.” Yes, this is true😀 #abberior #science #microscopy pubs.aip.org/physicstoday/a…
A noninvasive imaging technique can track the motion of single biomolecules in live cells. Learn more in Science ⬇️ 📄: scim.ag/24q 📄: scim.ag/24r #SciencePerspective: scim.ag/24s
A noninvasive imaging technique can track the motion of single biomolecules in live cells. Learn more in Science ⬇️ 📄: scim.ag/22g 📄: scim.ag/22k #SciencePerspective: scim.ag/22j
📣New article about the updated version of the #fluorescence #MINFLUX #microscope 🔬. This #cuttingedge technology allows for detailed observations of the tiny movements of individual proteins like never before 👉 bit.ly/3JSgd6d #microscopy #science #research
Published in Science: "MINFLUX dissects the unimpeded walking of kinesin-1" by Jan O. Wolff, Lukas Scheiderer, Tobias Engelhardt, Johann Engelhardt, Jessica Matthias and Stefan W. Hell. science.org/doi/10.1126/sc… @ScienceMagazine @mpi_mr_hd #MINFLUX #Fluorescence #Microscopy
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