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very few people have ever eaten the glass of going from nothing to something. idea → design → build → launch. that full arc. with or without ai, it’s brutal. it breaks your back & your brain. it’s one of the most honest pains there is.
so many people in silicon valley quietly made generational wealth by hopping from startup to startup as early execs or first 50 hires. they skipped the existential risk founders take, no sleeping on couches, no pre product despair just slid in once the core idea was already…
My hot take: The vertical AI products that will win are not the ones with the most sophisticated models or techniques - but those with the best system for incorporating domain expertise. The LLMs in the product need to understand the industry-specific and customer-specific way…
Vibes or nothing
Let's just add AI agent is never what you think it will be
Curious how many days of day this is based on and was this reflective of generally accepted science or did you find personalized findings?
Curious how many days of day this is based on and was this reflective of generally accepted science or did you find personalized findings?
Time for Kumon gyms for adults to keep you sharp
Time for Kumon gyms for adults to keep you sharp
this boring business owner tells you exactly how to sell AI to small businesses they don’t care about using “AI” in their biz. All they care about is: > saving money > making things faster & smoother. use accordingly.
i left my 6 figure job to pursue my passion
I've asked this before, but have yet to receive an answer: For my VC followers, what is your theory of AI/AGI that lets you fund a venture with a 5-9 year exit horizon and feel good that it will not be disrupted by AI? Investment patterns don't match VC talk about AGI timelines.
This is eerily close to my own hit rate of about 5% If we'd actually be able see the graveyard of 95% of founders, the argument to go all in for 10 years on one startup increasingly makes less sense The odds that you win are miniscule but you do end up wasting the best years of…
This is eerily close to my own hit rate of about 5% If we'd actually be able see the graveyard of 95% of founders, the argument to go all in for 10 years on one startup increasingly makes less sense The odds that you win are miniscule but you do end up wasting the best years of… https://t.co/XXSu7jkUEc
Demo day @Replit today and all I can say is SaaS is so cooked. The throwaway apps we build every day just to test new agent features would be raising 2-5M pre-seeds 5 years ago. Never been a better time to be a builder.
For decades, the startup world has pushed one narrative: you need co-founders to succeed. What if they’re wrong? The case for @solofounding:
ENTERPRISE AI: BUILD AGENTS, NOT TOOLS In the past 2 weeks, I've met several AI agent tooling startups that have each realized that the biggest problem in large enterprises is NOT the tooling to build, test and deploy agents, but that these enterprises don't have the talent…
A checklist for secure vibe coded apps. Putting things on the internet is kind of like parking your car in San Francisco—there's inherent risk. 😅 Luckily, there are some straightforward things you can do to minimize those risks. Here are 16 simple things to make secure vibe…
With AI, "we did 1,000,000,000 years of PHD time in one year." Nobel Prize Winner and @GoogleDeepMind CEO @demishassabis on AlphaFold, the groundbreaking AI system developed to solve one of biology’s most complex problems: protein folding.
People still laugh about indie hacking as a lifestyle business But if you do $3M revenue at 80% profit with 20% corporate tax and you can keep that up for 10 years (seems doable) You've made $33,694,455!
People still laugh about indie hacking as a lifestyle business But if you do $3M revenue at 80% profit with 20% corporate tax and you can keep that up for 10 years (seems doable) You've made $33,694,455!

kamal @kamal
6K Followers 1K Following Serial employee. 2nd engineering hire at @envoy. Prev: @viki (acq). 🇲🇾
Larry Gadea @lg
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Jay Ganatra @JayRGanatra
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SibylHardy @E983Sy542f39cmn
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MergerArbPro🇺🇸 @Ouqueagtui3514
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Kapaw @Kapaw354
33 Followers 772 Following If a person does not know which end he wants to sail to, then any wind is not a tailwind.
ShareholderYield🇺�... @Acica5511301
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Tammy @poillkj42
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Alyssa @vallyautey
532 Followers 3K Following I support Trump. I agree with his economic policies, his tough foreign policy stance, and his support for America First. I think his leadership style is straigh
Anna @AnnaLee1635225
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Jrod @MloneyJrod
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Toatharst @ToatharstXWlM0
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Tyrel Bahringer @bahringer771
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Joseph Michelli, Ph.D... @josephmichelli
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Aaron Levie @levie
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Suhail @Suhail
386K Followers 510 Following Founder: @mixpanel, next: 🤖🦾🦿 Pizzatarian, programmer, music maker
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Brian Roemmele @BrianRoemmele
390K Followers 39K Following we can only see what we think is possible...
Lenny Rachitsky @lennysan
266K Followers 3K Following Deeply researched product, growth, and career advice | Newsletter: https://t.co/LF0tRFpCeT | Podcast: https://t.co/ZQWNT0iXvJ | Lennybot: https://t.co/TqkCh3hVCa
kamal @kamal
6K Followers 1K Following Serial employee. 2nd engineering hire at @envoy. Prev: @viki (acq). 🇲🇾
Esther Crawford ✨ @esthercrawford
100K Followers 3K Following product leader. big tech (meta & twitter) and little tech (last startup acquired by twitter). owner of a short term rental 1hr north of SF. link below 👇🏻
Adam Singer @AdamSinger
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Hiten Shah @hnshah
269K Followers 5K Following Posts about Business. Building SaaS for 20+ years. Started https://t.co/xrOkg6UWaz (2005), KISSmetrics (2008) & https://t.co/uA827W8uqv (2020). What are you building? 🙏
Heather Knight @hknightsf
53K Followers 2K Following San Francisco bureau chief for the New York Times; former columnist for the San Francisco Chronicle and co-host of #TotalSF podcast; proud to call SF home
Semil @semil
154K Followers 849 Following Investor via @HaystackVC focused on seed-stage investments // Venture Partner w/ @LightspeedVP
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Bob Wachter @Bob_Wachter
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villi @villi
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Eugene Yan @eugeneyan
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PsyMed Ventures @PsymedVentures
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Aaron Tan @aaronistan
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Rhizome @rhizome
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quinn @quinnslcm
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Brian Balfour @bbalfour
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Calvin French-Owen @calvinfo
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Turbine Traveller @Turbinetraveler
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Molly O’Shea @MollySOShea
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124K Followers 2K Following Architecture, Engineering and Construction | Interior Design | Craftsmanship | Real Estate | Landscape | PM & FM https://t.co/qoXtZ4Qtny
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Jason Shuman @JasonrShuman
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swyx 🇸🇬 @swyx
125K Followers 3K Following achieve ambition with intentionality, intensity, & integrity - @smol_ai - @dxtipshq - @sveltesociety - @aidotengineer - @coding_career - @latentspacepod
jason liu @jxnlco
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Nozz @NoahEpstein_
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Christina Farhat @farhatchristina
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Thariq @trq212
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Workflow86 @workflow86
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Subaita @subaita_rahman
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kache @yacineMTB
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Broke Bibliophiles Ba... @BibliophilesBlr
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Ian Sigalow @Sigalow
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Sri Batchu🇺🇸 @sri_batchu
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Builders who Run @builderswhorun
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Merge Club @mergedotclub
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Seema Amble @seema_amble
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Philippe Laffont @plaffont
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Leaders 𝕏 Junction @LeadersJunction
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Dité @GashiDite
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Justine Moore @venturetwins
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Jason Warner @jasoncwarner
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cat @_catwu
39K Followers 355 Following claude code pm @anthropicai prev: @indexventures, @dagster, @scale_ai