addison_webster @addisonwebster0
how does the brain regulate appetite and metabolism? 🧠 UVA PhD student in the Campbell Lab Joined March 2022-
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Happy to share our work on hippocampal inflammasome signaling. Thank you to members of the lab for critical experimental support, @BIG_Center_UVA colleagues for input, and @LukensJohnR for baller mentorship - it's been an honor working with you all! cell.com/immunity/fullt…
I’m excited to share our publication from @Dulac_lab in @Nature, where we illuminate the development of hypothalamic cell types involved in a broad range of functions, from social behaviors to thirst, thermoregulation, and sleep. Highlights below! 🧵 nature.com/articles/s4158…
🚨 New paper in @Nature! 🚨 We’ve mapped the human hypothalamus in unprecedented detail, revealing key differences from mice & unlocking insights into obesity, metabolism & drug development. Meet HYPOMAP—a cellular Google Maps for the brain’s metabolic control centre. 🧵(1/)
You just can't leave the dessert even though you're full? 🍰 Blame it on your POMC neurons!🧠 (details ➡️🧵) Congratulations to Marielle Minère, @FenselauHenning and all other authors for their newest publication @ScienceMagazine ! 🎉 science.org/doi/10.1126/sc… 1/3
A dedicated neural circuit through which small molecule GLP1RAs modulate reward processing, suggesting broad therapeutic potential in conditions of dysregulated dopamine signaling including substance use disorder and binge eating pubmed.ncbi.nlm.nih.gov/39763823/
A little late for Thanksgiving but if you have friends and family members curious about anti-obesity medications, this is very easy to digest piece (nailed that pun....still got it) authors.elsevier.com/a/1kCED3QW8S6G…
Molecular connectomics identify local inputs to AgRP neurons and reveal a circuit through which GLP-1RAs suppress appetite in mice @NatMetabolism nature.com/articles/s4225…
New work stemming from an amazing collaboration with @addisonwebster0 and @AUGCsoup using a combination of rabies mapping and single cell sequencing to identify a GLP1R-expressing local input to AgRP cells that curbs appetite rdcu.be/d2gB5
Proud to share our recent collaboration, which combines rabies tracing with single cell sequencing to identify a novel GLP1R-expressing pre-syanptic partner to AgRP neurons @AUGCsoup @michael_krashes rdcu.be/d2gB5
The first opus of @mrbrown715's thesis work is now live in @GLIA_Journal, exploring the role of enteric glial cells in antigen presentation! onlinelibrary.wiley.com/doi/10.1002/gl…
Genetically defined neuron types underlying visuomotor transformation in the superior colliculus: nature.com/articles/s4158… "Here, we review these recent discoveries on the cell types and neuronal circuits underlying visuomotor transformations mediated by the superior colliculus"
🎉 New research group "Neurogenomics" headed by Lukas Steuernagel! 🧠🔬 Lukas dives into the fascinating world of the hypothalamus with a focus on bioinformatics. @CECAD_ @CGA_age sf.mpg.de/2098313/lukas-…
Sarm1 is not just for axons anymore. Check out our new preprint. Congrats to Katya Stepanova and the team. biorxiv.org/content/10.110…
Congratulations @Lowensteined @LiLi_Phd2017 Jason Le, @_anngru_ @oatneill @ForrestDRogers_ @addisonwebster0 @ivancalcantara @FrontalCortes !! #HypoGRC
Congratulations @Lowensteined @LiLi_Phd2017 Jason Le, @_anngru_ @oatneill @ForrestDRogers_ @addisonwebster0 @ivancalcantara @FrontalCortes !! #HypoGRC
🚨Paper alert! Exiting new research from the Fenselau and Brüning lab discovered a mechanism of synaptic plasticity that controls hunger and anxiety signaling by tuning neurocircuits depending on the energy level. 🧠 @NatureComms nature.com/articles/s4146…
UVA Brain Awareness Outreach is hosting an art show featuring pieces made by UVA researchers & Cville HS students based on research by UVA Neuroscience & Biology. The show will be up 3/22-3/31 @ The Bridge Progressive Arts Initiative (306 Main St.), entrance is FREE!
🌟 Good News: Wir fördern als #DAAD ab April 114 Projekte an über 100 🇩🇪 Hochschulen, um internationale Studierende stärker als zukünftige #Fachkräfte zu qualifizieren. Rund 120 Mio. € stehen bis 2028 vom @BMBF_Bund dafür bereit. #Bildungszukunft fcld.ly/ja4pvfn 👏👏👏
Why do we love cake and ice cream? My lab's latest paper in @Cell_Metabolism led by @molly_mcdougle identifies separate gut-reward circuits for fat and sugar. Foods combining fat and sugar recruit both reward circuits to increase motivation to overeating. authors.elsevier.com/sd/article/S15…
Why do we love cake and ice cream? My lab's latest paper in @Cell_Metabolism led by @molly_mcdougle identifies separate gut-reward circuits for fat and sugar. Foods combining fat and sugar recruit both reward circuits to increase motivation to overeating. authors.elsevier.com/sd/article/S15…
I wrote down my rules on how to Science. I hope you find it useful!
Congrats to @JingCai_1 on her new publication in Neuron @NeuronCellPress cell.com/neuron/fulltex… of the preprint biorxiv.org/content/10.110… with significant update thanks to insightful comments from reviewers. Thanks @yulonglilab @DrYongXu1 and others for help!
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