alexandre janer @alexostomate
Joined December 2013-
Tweets27
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Following133
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Thrilled to share the last review of the lab led by @Tabara_LC and @MayukoSegawa on the mechanisms regulating mitochondrial morphology!!! @MRC_MBU Just out in @NatRevMCB. Thanks @lisa_heinke for the smooth editorial process!
Thrilled to share the last review of the lab led by @Tabara_LC and @MayukoSegawa on the mechanisms regulating mitochondrial morphology!!! @MRC_MBU Just out in @NatRevMCB. Thanks @lisa_heinke for the smooth editorial process!
Check out our latest pre-print with @hauke_hillen and @VuckoviccAna, where we show that FASTKD5 joins RNase P and RNase Z in processing mitochondrial RNA. FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites biorxiv.org/content/10.110…
Montreal MitoClub MAY 7 at IRCM, 3-5PM! Join us for some exciting new work from the Estall and Topisirovic labs plus a guest speaker Anant Parekh from Oxford. See poster for details. Join us!
Brenda Milner compte parmi les scientifiques les plus importants de l'histoire de la neuropsychologie. Récemment, elle a parlé à @PhilMercure de @LP_LaPresse de sa vie, de son travail et de son quotidien à l'âge de 105 ans. buff.ly/49xgC9a
Check out this new pre-print from the Shoubridge lab! Congrats Jana and all!
Check out this new pre-print from the Shoubridge lab! Congrats Jana and all!
Check out the Shoubridge lab's latest story on SLC25A46 and its involvement with lysosomes and cholesterol trafficking in our preprint: biorxiv.org/content/10.110… @HAntonicka @alexostomate @TheNeuro_MNI @mcgillu special thanks to @kwattever from @karolinskainst #Mito #Mitochondria
How we think and talk about mitochondria matters to our science and to newcomers in the field. The powerhouse analogy is expired and we need specific vocabulary to capture the beautiful complexity of mitochondrial biology. We propose a framework and some nomenclature.
Une génération de chercheurs perdue, faute de financement ici.radio-canada.ca/nouvelle/20494…
We are happy to welcome you to the 8th EMBO/FEBS lecture course on “Mitochondria in life, death and disease” in September 2024 in Landshut (close to Munich, GER). #EMBOmitochondria. Registration will open April 1st. meetings.embo.org/event/24-mitoc…
If you're in Montreal, join us for our 3rd Montreal Mitochondrial Club meeting next week at CRCHUM on Tuesday 16 January, 3-4.30pm. We have three exciting talks by early-career scientists who will discuss mitochondrial transport, stress, and dynamics.
Congrats to @alexostomate and Jordan Morris for this study! And thanks to everyone involved @AaltonenMariJ @MichielKrols @HAntonicka !! It was a pretty cool collab with the E. Shoubridge's lab and @gingraslab1.
Congrats to @alexostomate and Jordan Morris for this study! And thanks to everyone involved @AaltonenMariJ @MichielKrols @HAntonicka !! It was a pretty cool collab with the E. Shoubridge's lab and @gingraslab1.
Check out this Research Article recently published in LSA: ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis@TheNeuro_MNI @alexostomate @ReviewCommons life-science-alliance.org/content/7/1/e2…
The Shoubridge lab (@TheNeuro_MNI) and @LabPrudent (@MRC_MBU) show that E-SYT1 acts at the ER-mitochondrial interface, partnering SYNJ2BP. Interestingly, lipidomics analysis shows that the effects of E-SYT1 knock down are rescued equally by E-SYT1 itself or artificial tether.
The Shoubridge lab (@TheNeuro_MNI) and @LabPrudent (@MRC_MBU) show that E-SYT1 acts at the ER-mitochondrial interface, partnering SYNJ2BP. Interestingly, lipidomics analysis shows that the effects of E-SYT1 knock down are rescued equally by E-SYT1 itself or artificial tether. https://t.co/0noaWruTxj
A protein complex composed of the outer mitochondrial membrane protein SYNJ2BP and the endoplasmic reticulum protein ESYT1 tethers the two organelles to facilitate calcium and lipid transfer @TheNeuro_MNI @alexostomate @ReviewCommons bit.ly/3QkNVEQ
It was a pleasure to collaborate with Toni (@Antonio41949078) and Hui on the role of iron–sulfur cluster assembly in mitochondrial ribosomes and multiple mitochondrial dysfunctions syndrome caused by BOLA3 or NFU1. Thanks also to @alexostomate @Mito_Crue academic.oup.com/nar/article/do…
Thank you to our collaborators: @LabPrudent @gingraslab1 @AaltonenMariJ @MichielKrols Jordan, Zhen and Hanish.
Another ER-mitochondria tether. Thank you @alexostomate and Eric Shoubridge for leading this project. ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis life-science-alliance.org/content/7/1/e2…
Check out our new paper in @LSAjournal on SLC25A46 and its role in mitochondrial fission and fusion: life-science-alliance.org/content/6/6/e2… @HAntonicka , @alexostomate
SLC25A46 is present at the tips of mitochondria, and at almost all mitochondrial fusion and fission sites. Check out the cool videos in the paper. #mitochondria #fusion #fission
SLC25A46 is present at the tips of mitochondria, and at almost all mitochondrial fusion and fission sites. Check out the cool videos in the paper. #mitochondria #fusion #fission

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PrudentLab @LabPrudent
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Isabella Straub @StraubIsabella
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Hana Antonicka @HAntonicka
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Jana Schuettpelz @JanaSchuettpelz
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CureMITO @cure_mito
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jobRxiv @jobRxiv
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