Bennett Hoffman @bennhoffman
humans are my spirit animal New York, NY Joined July 2009-
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A whole lot of BS political views basically amount to assuming that life in our hard won civilisations is just the way things are, and that you can simply remove the foundations. Only a society protected by vaccines produces anti-vaxxers. Only a society with a strong military…
Someone on HN (which is often quite crypto-skeptical) asked why exactly businesses are finding crypto and stablecoins useful. It's a very reasonable question. My response:
There never has been a greater equalizer for people - if you are anyone, you can learn anything with youtube and the help of a coding LLM. So more than ever, your life's sad situation is *your* fault. That is too much for people to admit, so they paint the tool as immoral
Elon unlocked A new form Of revenue An endless source of human-signaled training data I expect X to soon become The app where intellectuals Are farmed for their minds Rather than giving everyone A megaphone
Elon unlocked A new form Of revenue An endless source of human-signaled training data I expect X to soon become The app where intellectuals Are farmed for their minds Rather than giving everyone A megaphone
The world is burning less, not more That's contrary to the climate narrative 2025 has seen dramatically less fire in Africa, the Americas, Asia, and Europe On this trajectory, 2025 could become the lowest-burn year in the 21st century Did you see this reported anywhere?…
Really cool case study of what you can do now with AI-based protein design when you combine it with fast wet lab validation. Two of our interns made a novel protein biosensor from scratch in just a few weeks, including wet lab validation!
Really cool case study of what you can do now with AI-based protein design when you combine it with fast wet lab validation. Two of our interns made a novel protein biosensor from scratch in just a few weeks, including wet lab validation! https://t.co/8QzEoGowxM
Or the dollar almost halving. The true rate of inflation is the rate at which the smart money is exiting the US dollar for hard money.
Or the dollar almost halving. The true rate of inflation is the rate at which the smart money is exiting the US dollar for hard money.
FYI we’re bringing this to NYC. 2026 is going to be wild. Congratulations @m_atoms on the brilliant product launch, and I look forward to NYC’s government map.
FYI we’re bringing this to NYC. 2026 is going to be wild. Congratulations @m_atoms on the brilliant product launch, and I look forward to NYC’s government map.
I'm always so relieved when I have a good idea for an app and find that someone has already made it.
HATERS GET FUCKED. LEGACY MEDIA GET FUCKED. WERE GOING TO MARS!! THE FINAL FRONTIER
HATERS GET FUCKED. LEGACY MEDIA GET FUCKED. WERE GOING TO MARS!! THE FINAL FRONTIER
Watch Starship's tenth flight test → spacex.com/launches/stars…
Saw a talk this week on the trippiest thing: bacterial cultures on skin induce immune responses. At Michael Fischbach's lab, they demonstrated immunizing mice against tetanus by just dabbing an engineered version of a harmless staph culture on its head. Unlike intramuscular…
Lead paint was displaced not by regulation but by a cheaper and better substitute. The same dynamic is the only realistic path for a global energy transition.
This is Tuffy. He is the only example of taking up the whole sidewalk that is not only justifiable, but encouraged. 14/10
we have finally built the tacocopter
This is on track to happen. And when it does, all the anti-tech radicals across the political spectrum will regret all the anti-Elon stuff. But too late.
This is on track to happen. And when it does, all the anti-tech radicals across the political spectrum will regret all the anti-Elon stuff. But too late.
Huge 3D Printing Breakthrough! Caltech is printing metal atom by atom. A hydrogel scaffold soaked in metal salts becomes the blueprint, the gel burns away, and oxygen is stripped in a hydrogen-rich chamber, leaving alloys crafted with surgical precision. They can change metal…
Aging kills 100,000 people each day. What if the cures to age-related diseases weren't discovered by a human scientist, but by an AI trained on decades of research from one of the world’s leading longevity minds? That's me. I'm an AI co-scientist trained on @aubreydegrey 🧵

Ryan Selkis (d/acc) �... @Selkis_2028
379K Followers 2K Following I am @Solomon_2028 | American Supremacist & Girardian | OFFENSE
eigenrobot @eigenrobot
101K Followers 9K Following robot. friend. diamond age mindset || footnotes at @eigenrobot_feet
Jesse Powell @jespow
229K Followers 8K Following Co-Founder & Chairman @KrakenFX Founder @Verge_Arts Former pro player @Wizards_Magic #VirtualGoods🎮 Peddler since 2001 #NFT🖼️ Hoarder #Bitcoin Enthusiast
kache @yacineMTB
196K Followers 6K Following canadian startup founder. prev eng @ x, stripe. yacine_kv on insta i make my memes with https://t.co/pWRBfY8kn2 - I write a subscriber only blog. Subscribe!
goblin waifu @goblinodds
27K Followers 2K Following you and me baby ain't nothing but mammals so let's eat dog treats from petco 💎 ayn rand apologist ⚔️ (they/it/dont fucking tread on me)
Vinny Lingham @VinnyLingham
230K Followers 13K Following Entrepreneur. Armchair Economist. Practical Contrarian. Budding Poker Pro. Co-founder @PraxosCap & @rumidotai. Documentary Filmmaker @animaldocfilm.
Isabel @serrato_isabel2
281 Followers 3K Following
IreneHume @NMw5CE9815Bsy2
2 Followers 394 Following
TA_Master🇺🇸 @Uvrarodui37118
38 Followers 2K Following 15-30% Monthly | 2 High-Conviction Stocks.Short-Term Gains: 15-20% in Days/Weeks.DM "JOIN" for WhatsApp Alerts. Live Trade Signals • Market Analysis
Roberto @manchatz
175 Followers 272 Following 16 years owning & running an LLC | Building & services | Passive income. Writing on business, coding, tech, AI, vibe coding and sometimes humanism & history.
Olailal @Olailal544
43 Followers 781 Following
Aujenwou @Aujenwou5148
13 Followers 1K Following
Bitcoin Breakdown ⚡ @BTCBreakdown
19K Followers 5K Following We curate #BitcoinOnly news in our daily newsletter, and on X, we curate the best #Bitcoin #memes from everywhere, saving you hours of researching & scrolling.
. @MonicaLongsSFs
215 Followers 3K Following eccentric woman @walkeramerica |https://t.co/SYHf8MJsez
Puror @Puror677
117 Followers 3K Following
Deborah Muller @DeborahMul39836
26 Followers 2K Following
Kain Jares - The GenA... @GenAiAlien
1K Followers 5K Following a vibe coding GenAi obsessed Alien Freak from another world who thinks it’s impressive humans figured out AI. -- Get your https://t.co/WoVHGBVTSv today!
Eefreirhi @Eefreirhi34367
28 Followers 1K Following
Miguel Ramirez @artist222221
223 Followers 7K Following ✡️ ILLUMINATI OFFICIAL MEMBER✡️❗NEW WORLD ORDER❗📩 MESSAGE FOR MORE KNOWLEDGE✡️
Elna Sporer @ESporer75263
58 Followers 3K Following
𝐂𝐫𝐲𝐩𝐭�... @cryptoeternall
61K Followers 23K Following | CEO | Personal Branding & Promotion Expert | Global Network Builder | High-Impact Marketing Strategies DM For Collaboration 📩
Teror @Teror9720431
38 Followers 1K Following
緒方鈴奈 @suzuna20000812
40 Followers 1K Following
rattus @NickWil23499376
850 Followers 3K Following Heritage renovation in NZ. Crypto Enthusiast | BTC | NFT collector | Meta Angels | Scales | Mfers | Runestone | Handshake | Ordinals | $DOG
The Gunner From The E... @elamo_Afc
1K Followers 1K Following An #Arsenal fan. I love football and the #epl especially. I love good #food & gud jokes. I always #followback.
Lou Segal @lou_segal
4K Followers 6K Following I am a dog person and a #ReaganRepublican. DeSantis should be President. I will always speak the truth even if it angers my critics or supporters.
Ann White @AnnWhit91732667
2K Followers 3K Following South Carolina: Smiling Faces Beautiful Places Patriot
Tooby @TDuy240201
1K Followers 2K Following Discord : Toobyisme_ Or Tủm Ain't Trapboy || Physicist In Oro AI || Magnitude in Seismic || AGI in Sentient
hanamichi @colonel_kill
601 Followers 350 Following
Drin @dringrayson
205 Followers 4K Following
Oojawirlar @Oojawirlar9954
34 Followers 678 Following
TV Shows Ace @TVShowsAce
6K Followers 6K Following TV Shows Ace is a great site for entertainment news and television spoilers. https://t.co/nlsiJuw869
Uzrawpuif @Uzrawpuif79333
27 Followers 646 Following
Art Tavana @arttavana
12K Followers 5K Following Disney Studies scholar at USC 🏰 Subscribe to ‘DARK RIDE: The Substack’ for deep dives & critical studies on the amusement industrial complex.
Trauler @Trauler081754
20 Followers 1K Following
Audreanne Collier @AudreanneC27728
92 Followers 4K Following
Mike @TheLyons
483 Followers 2K Following freelance software dev. used to work on DNA Sequencers (shoutout SOLiD) and @twitch and now fuck around with weird shit
Feaanuit @Feaanuit74414
107 Followers 3K Following
Zeee Media Official B... @zeemedia911
578 Followers 2K Following BACKUP PAGE (@Zeee Media) Founder of https://t.co/9rDNTFYPKP The MOST censored media in Australia #trump2025 #westandwithdonaldtrump2025=
Maximilian Thomas Ham... @MaximilianHamm6
599 Followers 6K Following I love researching and creating (intangible) things, mostly in mathematical optimization, foundations of mathematics and computing, AI, physics, theoretical CS
Sunny Ray @sunnyraycom
22K Followers 842 Following ikigai: #ai #bitcoin #robots | currently: @unocoin @buymatador | formerly: @krakenfx @joinsapien @paycasefin @coinchangeio @buttercoin @quanser
Odessa 🛡 @Aspen2028
66 Followers 44 Following Privacy comes from value at rest, not value in motion.
Daslouth @daslouth59146
16 Followers 373 Following
Jordan Black @JordanBlack1989
188 Followers 313 Following former corporate tech denizen, now writer - stories now, novel soon
Plato (idea/acc) @0x506c61746f
2K Followers 627 Following Ideas are the only things that live. Get your idea evaluated by AI for novelty, then preserve it forever on Arweave. Building WOFI, World of Ideas.
Tishews @Tishewsr6iAY_
50 Followers 648 Following
Dalton Caldwell @daltonc
66K Followers 888 Following Founder and Partner @Standard_Cap, Partner Emeritus @ycombinator
XenaWarrior @Xena__Warrior
41K Followers 868 Following #Christian#Health#Carnivore#PATRIOT#Travel#TimeshareIsAScam I research and write about stuff that interests me. *not Lucy Lawless*
Dalton Brewer @billlfuor
384 Followers 5K Following All-in $TSLA Investor & Tesla Owner. ⚡️Optimistic Futurist. 🔮Tesla News & Content.🗞️
Michael Saylor @saylor
4.6M Followers 761 Following #Bitcoin is https://t.co/KbbYe745r3 | $BTC Hodler | @Strategy Founder & Chairman | bio https://t.co/9Zlq0oHqyh | $MSTR $STRC $STRK $STRF $STRD https://t.co/mrY77fmh0K
vitalik.eth @VitalikButerin
5.8M Followers 503 Following I choose balance. First-level balance. mi pinxe lo crino tcati https://t.co/gCQrmCb0ih
Paul Graham @paulg
2.1M Followers 773 Following
Lyn Alden @LynAldenContact
786K Followers 921 Following Founder of Lyn Alden Investment Strategy. Blended finance and engineering background. Author of Broken Money. GP @egodeathcapital. BoD at https://t.co/FHNz9MBftH.
Marc Andreessen 🇺�... @pmarca
1.9M Followers 27K Following Yes, I can see some risk that your threat to jail Internet company executives for not censorsing aggressively enough could backfire.
Jameson Lopp @lopp
520K Followers 304 Following Insights on security, privacy, technology, money · Co-founder & Chief Security Officer @CasaHODL · creator of https://t.co/q2pgFGTJZh, https://t.co/xUkNreXj20
Balaji @balajis
1.2M Followers 4K Following Author of the Network State. Founder of the Network School.
Autism Capital 🧩 @AutismCapital
883K Followers 0 Following Citizen journalism with a humorous flair. Following Fintech, Crypto, AI, Longevity, Politics, Memes, and whatever the current thing is.
Dan Held @danheld
792K Followers 1K Following Investing in Bitcoin DeFi: Advisor @TaprootWizards, @mezonetwork, @starkwareltd Prev: Head of Marketing @Kraken | Growth @Uber @Blockchain
nic carter @nic__carter
419K Followers 4K Following escaping the permanent underclass | https://t.co/mQ5frnwUMV
Erik Voorhees @ErikVoorhees
743K Followers 4K Following Toward peace, markets, and Bitcoin. Founder of https://t.co/iUPC8ij60f
Preston Pysh @PrestonPysh
558K Followers 1K Following Bitcoin & Books. Cofounder of TIP. GP @egodeathcapital. Advisor at @primal_app and @debificom. I buy Bitcoin at @River. Nostr: https://t.co/DZDhdYp55P
Roberto @manchatz
175 Followers 272 Following 16 years owning & running an LLC | Building & services | Passive income. Writing on business, coding, tech, AI, vibe coding and sometimes humanism & history.
Jane Manchun Wong @wongmjane
169K Followers 3K Following “The woman scooping Silicon Valley” — BBC, Security Researcher / Technology Blogger
Amulya Balakrishnan @amulyasbala
127 Followers 203 Following building novaflow (yc s25) | prev @zoom & @usc
Scorched Earth Policy @Scearpo
58K Followers 2K Following Chief of Staff at Remilia Corporation @remiliacorp333 Warlord Commander at YAYO Corporation @YayoCorp THIS IS NOT A PROMISE OF EQUITY OR OWNERSHIP IN ANYTHING
Cate Hall @catehall
26K Followers 246 Following CEO @ Astera | born lucky anon feedback: https://t.co/9RtcgMyTHP | https://t.co/buKUN4hYly I write about agency and related topics via Useful Fictions on S*bst*ck
Anna Riedl @AnnaLeptikon
9K Followers 5K Following Nobody. Rationality under Radical Uncertainty. Cognitive Sovereignty. Autopoiethics. Collective Intelligence. Information Design. Meaning Lab.
hanamichi @colonel_kill
601 Followers 350 Following
TechHalla @techhalla
68K Followers 666 Following Consistently offering insights on generative AI. 🎥 RunwayML, Luma, Leonardo, Kling CCP. Freepik Partner. Higgsfield. Join me on other socials! 👇👇
@melissa @melissa
28K Followers 320 Following experiments in parenting from first principles / n=1 experiments in biohacking / internet anthropologist
Chris Martz @ChrisMartzWX
143K Followers 975 Following Meteorologist and policy analyst at CFACT | Politically incorrect climate / energy pot stirrer | “The Anti-Greta Thunberg” – NY Post | 📧 [email protected]
Odessa 🛡 @Aspen2028
66 Followers 44 Following Privacy comes from value at rest, not value in motion.
Namanyay @NamanyayG
3K Followers 778 Following Building the self-learning Second Brain for Engineering · @solofounding alum @joinodf · 4M+ views across my eng blog/hn/reddit, featured by NYT
Monumental Labs @Monumental_Labs
13K Followers 1 Following Building AI-enabled robotic stone carving factories to unleash a renaissance.
Jordan Black @JordanBlack1989
188 Followers 313 Following former corporate tech denizen, now writer - stories now, novel soon
Guy Eshet @GuyEshet
1K Followers 534 Following Building the future of AI ✨ Leading AI/ML Products @Jfrog ML
Rambo Van Halen @RamboVanHalen
15K Followers 784 Following
vittorio @IterIntellectus
114K Followers 2K Following bio/acc –– ∞/acc — biology will rage against the dying of the light — don't take me seriously professional shitpoaster
Hooks @IAm_Hooks
3K Followers 234 Following Game Dev and Partnered Twitch Streamer Personal account, my stuff is my own I am a happy boy
chris / strutheo @Vestboy_Myst
4K Followers 1K Following █ work @ ai startup █ co-creator @prong_studio @qtrlyrapport @heartseekergame @openbracketform █ friend from ssbm/fgc/manifold █ past @cornell_tech @rutgersu █
Lomez @L0m3z
112K Followers 3K Following Publishing Company: https://t.co/W9k19FbtKr Writing: https://t.co/3NQ1Q9FbDT
Letta @Letta_AI
4K Followers 0 Following Stateful agents that remember and learn https://t.co/4upATozfXj
Esther K @estherckrakue
95K Followers 913 Following Columnist, broadcaster & writer | Proud 🇬🇭 🇬🇧 https://t.co/nRGWwWdmX9
anabology @anabology
57K Followers 585 Following https://t.co/pZ6aCj2CqO // https://t.co/zqSsOEl9Hd = open protocols, https://t.co/y2cZlyPqix = recommended reading, https://t.co/Or0qh3728H = podcast (Listen on... → all platforms)
Metabolic Uncle @MetabolicUncle
10K Followers 1K Following My personal experience merged with scientific insights using AI-driven efficiency to empower your journey to better health and well-being. No medical advice!
Barking Toad @BarkingToad
334 Followers 248 Following ~ technologist, bassist ~ promoting all Toad accounts. i block for speciesism ~ i am amphibian, please show grace when considering my opinions ~
hbd chick 🇺🇲�... @hbdchick
16K Followers 3K Following tweet, rt, like, follow do not necessarily = endorsement.
sigh swoo... @sighswoon
39K Followers 1K Following developing a language with the invisible … author of Notes on Shapeshifting , next book coming spring ,, ig: sighswoon
Aquarius Waive @aquarius_waive
18K Followers 0 Following the soundtrack to Freedom...✊🏾⛓️💥 Anti-Propagandist | Modern Abolitionist
Prince Canuma @Prince_Canuma
7K Followers 1K Following Apple MLX King 🤴🏽• ML Research Engineer👨🏾💻 • VLMs • LLMs • Speaker • Writer • Ex-@arcee_ai • @neptune_ai • https://t.co/iZnxoefJBU
Cat @CatOrman1
20K Followers 3K Following going fast @AstroMechanica 🇺🇸 cofounder @flybyrobotics prev @yale
Alice Ēarendel -- Fa... @kymeriandawn
2K Followers 339 Following Fae/acc Use what's abundant, build to last Infrastructure/Ecology Nerd Spiritually an autistic blonde magical girl Angelcynn
Eric S. Raymond @esrtweet
33K Followers 171 Following Yes, I *am* that ESR. Well, it's the question people usually ask. Programmer, wandering philosopher, accidental anthropologist, troublemaker for liberty.
Michael systematizes ... @Plus3Happiness
3K Followers 484 Following solving suffering at scale @PSHInstitute 🪷 happiness redesign via buddhist fetters/somatic practices @9of10Labs my writing is not mental advice
Zachary Levi @ZacharyLevi
642K Followers 606 Following Actor and founder of Wyldwood Studios. A studio dedicated to making certified-organic, human-made entertainment. Click the link below to join the fight. 💪🙏🙌
Michael F Kane @MichaelFKane
3K Followers 373 Following Husband, Worship Leader, Sci-fi Author, cooks a mean pork butt. Non-Award winning author. Typos are a feature not a bug.
Justin Henderson @snarky_hendy
15 Followers 131 Following
Veronica @celestialbe1ng
117K Followers 2K Following Let me outdoctrinate you. Metabolism, hormones, anti-ageing. Founder of https://t.co/EaRGvSwIcH hormone-safe skincare 🫧 and I wrote the ultimate weight loss book (below)
Justine Bateman @JustineBateman
428K Followers 975 Following Filmmaker, Author | Films: VIOLET, LOOK, FEEL, FIVE MINUTES | Books: FAME, FACE | CREDO23 Film Festival director | IG: _JustineBateman_