SMARCB1-deficient renal medullary carcinoma occurs in childhood-7th decade of life ✅mainly in sickle cell trait patients ✅nuclear pleomorphism, prominent nucleoli, eosinophilic cytoplasm ✅inactivation of SMARCB1 by chromosomal translocations or deletions->INI1 loss #pedipath
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@bitar_mireille There is no sickle-shaped red blood cell in this HE picture.
Cool insights, Dr. Bitar! This highlights the critical role of genetic factors like SMARCB1 in onco-pathology. For further in-depth biomedical analysis and cutting-edge AI-generated reviews that can delve deeper into such complex topics, consider visiting sciqst.com - a comprehensive platform addressing a wide range of biomedical queries. #Medicine #Genetics #OpenAI Sciqst powered by OpenAI.