Brian Glancy @brianglancylab
Muscle Energetics Laboratory. We study how muscles are built to sustain power with a focus on mitochondrial energy metabolism. Bethesda, MD Joined August 2019-
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So excited to finally see this work published! 🙌 #PLOSONE: An optimized approach to study nanoscale sarcomere structure utilizing super-resolution microscopy ... dx.plos.org/10.1371/journa… #myotwitter
Ran across this yesterday in our TEM imaging. Muscle nuclei have feelings too😆
Now published @jclinicalinvest, @Piya_Siripoksup, a recent graduate from @UofUDMRC, demonstrates that sedetariness induces metabolic inflexibility by reducing pyruvate entry into mitochondria. doi.org/10.1172/JCI167…
Today, we report that IF1 is a cold-regulated switch of ATP synthase to support thermogenesis in brown fat. 👇 biorxiv.org/content/10.110…
What do mitochondria look like? A little look at mitochondrial diversity by electron microscopy Source: picardlab.org/uploads/7/7/8/…
I am searching for a postdoc to join us in Padova from the summer! If you like muscle imaging (with muscle ultrasound experience) and neuromuscular/exercise physiology, drop me a line. Background in Physiology/Biomed Eng/Sports Science/Biology? 📨[email protected]
I am searching for a postdoc to join us in Padova from the summer! If you like muscle imaging (with muscle ultrasound experience) and neuromuscular/exercise physiology, drop me a line. Background in Physiology/Biomed Eng/Sports Science/Biology? 📨[email protected]
Check out our latest preprint @biorxivpreprint led by the newly minted Dr. @JTylerHagen 👇 In it, we investigate the peculiar bioenergetic phenotype of AML with the goal of identifying cancer-cell intrinsic mitochondrial physiology potentially actionable to treat the disease.
Check out our latest preprint @biorxivpreprint led by the newly minted Dr. @JTylerHagen 👇 In it, we investigate the peculiar bioenergetic phenotype of AML with the goal of identifying cancer-cell intrinsic mitochondrial physiology potentially actionable to treat the disease.
ahajournals.org/doi/abs/10.116… Please check out our latest paper that explores the relationship between Ca2+ and ROS in regulating mitochondrial dysfunction. Great work @Arielys_Mendoza!
@EJokitalo @EuroBioImaging @VolumeEM1 The paper link: nature.com/articles/s4155…
More great work from @AtHinton lab has led to the front cover & inside cover. Thank you @IntMedAbel for your mentorship! Thank you @KattiiPrasanna for being my co-first & thank you, Drs. @brianglancylab & @RePereira Thank you @WileyGlobal Press & the Journal of Cell Physiology
More great work from @AtHinton lab has led to the front cover & inside cover. Thank you @IntMedAbel for your mentorship! Thank you @KattiiPrasanna for being my co-first & thank you, Drs. @brianglancylab & @RePereira Thank you @WileyGlobal Press & the Journal of Cell Physiology https://t.co/lskoRXlk1s
Neat application of the lifetime biosensor Tq-Ca-FLITS for quantiative, pH-insensitive measurements of Ca2+ in mitochondria: sciencedirect.com/science/articl…
Right place at the right time: Mitochondrial shape, distribution and inter‐organelle interaction during skeletal muscle postnatal development - Jesus - The Journal of Physiology - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/full/10.11… @JPhysiol
I'm looking for a postbac fellow to help with our muscle and mitochondrial disease mouse models. Some experience with mammalian models, genetics, and/or molecular biology preferred. Come join us for one year as you prepare for graduate/medical school. Contact me if interested.
Attention organelle enthusiasts!! I am beyond thrilled to introduce Nellie: a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D/3D live-cell microscopy. paper: arxiv.org/abs/2403.13214 github: github.com/aelefebv/nellie 🧵1/N
My kudos to @brianglancylab and team for this fantastic work on mitochondria organization in skeletal muscle. Spoiler alert, not all mitochondria are the same 🤌🏼❤️ physoc.onlinelibrary.wiley.com/doi/10.1113/JP…
New Tenure-track position at McGill University (Montreal, Canada) in Applied Sports Science. Deadline to apply: May 15th (hope the link works!! 🤞) mcgill.wd3.myworkdayjobs.com/McGill_Careers…
Hi #myotwitter! Enjoy my latest selection of papers on skeletal muscle plasticity with health, disease, aging, and exercise. 👇 biomed.news/bims-moremu/20… This week highlights from: @brianglancylab @yan_burelle @GabKardon Thanks @Bims_BiomedNews
A #JournalClub submission from @Jaydeep_Sharma_, @somnath_im and @MahimaK2104 (@unescorcb) discusses how mitochondrial calcium for skeletal muscle performance and function... 📜buff.ly/3U1R8MG
Drs. @parry_hailey, @yuho_kim, Brian Glancy (@brianglancylab), & collaborators report that proximity to capillaries has a greater impact on resting mitochondrial energy conversion and distribution in #SkeletalMuscle than the #sarcolemma alone. @JPhysiol bit.ly/4aked2H
Delighted to announce that our new paper is now available online! Congrats to all authors and @dgsomucla for their invaluable support. Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria | Science Advances science.org/doi/10.1126/sc…
Kevin Murach @KevinMurachPhD
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Matthew S. Alexander @Matt_Muscle_Guy
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EM Research Services... @EMRSncl
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Professor Adam Sharpl.. @DrAdamPSharples
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David J Glass MD @davidjglassMD
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Julien Ochala @OchDr
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Juleen R. Zierath @JuleenRZierath
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Christopher Fry @ChrisFryPhD
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Gilles Gouspillou @GGouspillou
1K Followers 951 Following Scientist interested in skeletal muscle physiology, mitochondrial biology and aging.
John A. Hawley @JohnAHawley
17K Followers 174 Following Exercise Physiologist. Lifelong athlete. Liverpool & All Blacks fan. Dad of Jack, husband of Louise. Losing the battle to match my VO2max to my age.
Journal of Physiology @JPhysiol
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311 Followers 1K Following Sports Scientist | Economist | Ecosocialist | Feminist | Wanderlusty | ✊🏼♥️🌿🌍
James Olzmann @OlzmannLab
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Ana Raquel Pereira, P.. @Pereira_ARR
572 Followers 895 Following 🔬 I like my microscopy in super-res 👀 Into big cells now 💪 Ancient gymnast🤸♂️typos are my own. (she/her)
Dharanibalan @KDharanibalan
76 Followers 422 Following Engineer- Biotechnologist. Research focused on microgravity, vasculogenesis, extracellular vesicles and skeletal muscle biology. Views on my own.
Enrique I. Oliver, Ph.. @EnriqueI_Oliver
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Carlos Guardia @Charly_Guardia
1K Followers 2K Following NewPI @NIEHS | Stadtman TTI | NIH DSP #2021 | Cell Biology - Autophagy - Intracellular Traffic - Placenta | My tweets are my own | 🇦🇷🏳️🌈🇺🇸
Nicolas Place @Nicolas_Place1
172 Followers 94 Following
Michael Joyner @DrMJoyner
16K Followers 615 Following Physiologist & anesthesiologist Interested in human performance, views my own. Posts & RTs do not = endorsement.
Samuel Bennett @samuel_bennett
830 Followers 979 Following Post-Doc at @TAMU_CBCR ⏰🐭🏃♂️ PhD in Exercise Physiology 🚴♂️🍝🥵 Contact Info: https://t.co/v7Uy6e8A8w
Javiera Albornoz @JavieraAlborn18
7 Followers 66 Following PE @umcecl @uniofjyvaskyla ; MSc. Physiology @uchile ; PhD student Biomedical Sciences @uchile.
Kholoud Saleh, PhD @khsaleh88
93 Followers 285 Following Muscle and stem cells. @uclamcip @UCLA Alum. A Proud member of QRLP @QNRF @QF. A Scientist, Researcher, Wife and Mom to two beautiful princesses
Wilson (Yuqin Wu) @Wilson79078233
556 Followers 4K Following PhD candidate at Monash BDI, study in Glucagon signalling in metabolic control (supervised by Dr Adam Rose, the head of Nutrient Metabolism and Signalling lab)
Some crazy folks decided to run a 3D imaging and computational biology class during Covid quarantine. It was a wild ride. Out of it came a nice little observer variation paper on how we landmark, segment and analyze 3D musculoskeletal features in CT data of Anoles. Thanks all!
Now in issue! Computational Approaches and Observer Variation in the #3D #Musculoskeletal Modeling of the Heads of #Anolis by Lagorio, McGechie, Fields, Fortner, Mackereth, C Perez, Wilken, Leal,Ward, Middleton & @CrocHolliday doi.org/10.1093/iob/ob… #science #biology #lizards
"This study will serve as a landmark platform to direct future studies related to both stem cell and muscle biology of human aging.” - NIAMS’ Vittorio Sartorelli on the Muscle Aging Cell Atlas.
Now with an associated Research Briefing: doi.org/10.1038/s43587… rdcu.be/dFCgI
Cal-ID, a calcium-dependent protein proximity labeling tool, is finally published @nchembio! We (@nickingolia) present a simple, scalable, in vivo compatible, and versatile platform that connects calcium signals to biochemical labeling of proteins. rdcu.be/dFDrb
Excited to see another stunning vEM publication from @HHMIJanelia using @thermosciEMSpec Amira software for visualization. ImageJ used for segmentation.
✨ New research, led by @YaChengLiao1 @JLS_Lab, details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions. 🦠 🔗janelia.org/news/starving-…
@brianglancylab @AbigailMackey1 @OchDr @DrMatt84 @Geoff_A_Power @MVFranchi Yep, full of mitos, microtubules, and many other things. The perinuclear area is amazing 🤩🔬😍
It’s Friday 🎉 #FluorescentFriday
@brianglancylab @manorlaboratory Or Ellen Breen, also at UCSD?
@brianglancylab Thanks for sharing, I think I missed this paper!
@phdgprotein86 @AtHinton @IntMedAbel @brianglancylab @RePereira @WileyGlobal @VUBasicSciences @VUmedicine @VanderbiltU This is great news! I'm happy to be part of this collaborative effort. Thanks, AJ and all the mentors for your guidance and support.
Learn more about @ACampbell_MRI's work leading the Laboratory of Imaging Technology: go.nih.gov/qmePFQJ
@JuFaitg @brianglancylab @parry_hailey @yuho_kim @JPhysiol 🥂 Congratulations to the team on this fantastic publications!
Definitely worth another read. It makes a lot of sense, but I'm slow to pick it up because it challenges a lot of assumptions I didn't know I had about skeletal muscle mitochondria. These ideas make a lot more sense than my previous assumptions . Very Cool physoc.onlinelibrary.wiley.com/doi/full/10.11…
🥳new R01 just dropped🎤 I'm grateful for @NIH_NIAMS support to study the role of HIF1 and hypoxia in musculoskeletal development and healing, focusing on the tendon enthesis, w/ an awesome collaborative team @KillianLab @YatrikShahLab @UMPhysiology @ClaudiaLoebel + Jun Hee Lee
Impact of capillary and sarcolemmal proximity on mitochondrial structure and energetic function in skeletal muscle - Parry - The Journal of Physiology - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/10.1113/JP…
@MitoPsychoBio @brianglancylab This is fantastic work 👏🏼
Beautiful example of mitochondrial diversity and specialization—within a given cell type Kudos @brianglancylab for the superb work bit.ly/4aked2H
Beautiful and needed work as always from @brianglancylab @parry_hailey @yuho_kim Congratulations!!! @JPhysiol
Drs. @parry_hailey, @yuho_kim, Brian Glancy (@brianglancylab), & collaborators report that proximity to capillaries has a greater impact on resting mitochondrial energy conversion and distribution in #SkeletalMuscle than the #sarcolemma alone. @JPhysiol bit.ly/4aked2H
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