Charlie Buchanan @charliebuchanan
🧪 DPhil Physical and Theoretical Chemistry in Baldwin Group @ University of Oxford 🚣🏻♂️ Boat Race Blue 2019 He/him Oxford, United Kingdom Joined July 2010-
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Charlie Buchanan retweeted
An integrative characterisation of proline cis and trans conformers in a disordered peptide biorxiv.org/cgi/content/sh… #biorxiv_biophys
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Protein fractals are a thing! BUT their beguiling looks can be deceiving - these have the hallmarks of being accidentally (and neutrally) evolved... Such interesting and beautiful work - congratulations @SendkerFL and the whole team!!
Protein fractals are a thing! BUT their beguiling looks can be deceiving - these have the hallmarks of being accidentally (and neutrally) evolved... Such interesting and beautiful work - congratulations @SendkerFL and the whole team!!
If there are two things I love they are protein dynamics and NMR - such a ferocious study - really beautiful and well done to the whole team! @DFlemmingHansen @bhu_vaibhav @SiemonsLucas
If there are two things I love they are protein dynamics and NMR - such a ferocious study - really beautiful and well done to the whole team! @DFlemmingHansen @bhu_vaibhav @SiemonsLucas
Charlie Buchanan retweeted
In our latest paper @PNASNews a tour-de-force analysis of #NMR CPMG data by @bhu_vaibhav shows, for mutants of HDAC8, that changes in enzymatic activity and inhibitor potency are all captured in the structural dynamics. @UCLLifeSciences @SiemonsLucas pnas.org/doi/10.1073/pn…
Charlie Buchanan retweeted
Our #NMRchat DNNs are now able to transform crowded HSQC spectra of large proteins (<350 kDa) into spectra akin to Methyl-TROSY (methyl-TROSY-fication). Read the full story on bioRxiv: doi.org/10.1101/2023.0… @EPSRC #DeepLearning @UCLLifeSciences @gogulan_k @bhu_vaibhav
Charlie Buchanan retweeted
We used #nativeMS electrospray ion beam deposition (ESIBD) to make samples for #cryoEM: mass-filtered, soft-landing deposition, cold substrate, in-situ ice growth, clean+cold transfer...we find... @ESIBDLab with many colleagues @OxfordChemistry @KavliOxford #structuralbiology
We used #nativeMS electrospray ion beam deposition (ESIBD) to make samples for #cryoEM: mass-filtered, soft-landing deposition, cold substrate, in-situ ice growth, clean+cold transfer...we find... @ESIBDLab with many colleagues @OxfordChemistry @KavliOxford #structuralbiology https://t.co/yX7wTcTdVs
Charlie Buchanan retweeted
If you’re gonna see Queen Beyoncé you must know the lyrics to Heated.
Charlie Buchanan retweeted
Certain structures (e.g. some carbohydrates) are notoriously immunorecessive. Check out our latest preprint describing a germline ‘reach-through’ model for glycan-specific B cell activation. biorxiv.org/content/10.110… (1/4)
Charlie Buchanan retweeted
Charlie Buchanan retweeted
BT made £1.3bn, gave £750m to shareholders and the CEO got £3.5m. We have members using foodbanks. Today BT announced £400m profit for 1/4 year. Tomorrow our members strike for the first time since 1987 and have been subjected to extreme intimidation. RT if you back them.
Charlie Buchanan retweeted
Royal Mail Group profits £758m Shareholder payout £400m Paying TWO CEOs £2m + Imposed 2% on loyal postal workers who kept the country connected during the pandemic. They’re using Swiss banks whilst our members use foodbanks. Ballot result Tuesday. RT if you back us.
Charlie Buchanan retweeted
@charliebuchanan’s (and other colleagues/collaborators) work being described by Ben Davis. @KavliOxford
Charlie Buchanan retweeted
Pembroke Chemistry Tutors, Prof Andrew Baldwin & Prof Ben Davis have collaborated with DPhil student @charliebuchanan on a new research paper which has been published in @ScienceMagazine! Read more here: bit.ly/3zZIPam
Charlie Buchanan retweeted
A study of #SARSCoV2 finds evidence for a sialoside binding site in the early-pandemic B-origin lineage. Binding is lost in later, more transmissible variants, consistent with hypotheses that such sites can vary and may contribute to fitness. #glycotime fcld.ly/dockjdx
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