Check out our methods paper on high-resolution cryo-EM analyses of nucleosomes is published! It covers nucleosome preparation, grid making, and single-particle analysis for cryo-EM. This work is a collaboration with the Danev Lab at the University of Tokyo.link.springer.com/protocol/10.10…
Check out our review article on noncanonical nucleosomes, which differ from canonical nucleosomes in their histone composition and DNA wrapping.
The article highlights recent insights into their structural and functional diversity.
sciencedirect.com/science/articl…
Check out our new preprint on H3-H4 octasome transcription by RNAPII!
We discovered that H3-H4 octasome is transcribed more efficiently than nucleosomes and visualized its transcription process by cryo-EM.
#cryoEMdoi.org/10.1101/2025.0…
New #CryoSPARC case study!
End to end #cryoEM processing of encapsulin and encapsulated ferritin, with a focus on challenges and strategies for handling mixed high-order and non-point-group symmetries. guide.cryosparc.com/processing-dat…
Cryo-EM structures of the human SET8-nucleosome complexes reveal the mechanism by which the SET8 methyltransferase binds the nucleosome and specifically recognizes the histone H4 lysine-20 residue by Kurumizaka & colleagues @UTokyo_News_enlife-science-alliance.org/content/4/4/e2…
296 Followers 704 FollowingScientist at @NCIResearchCtr, National Cancer Institute, NIH. study #Chromatin, interested in #cryoEM, all opinions are my own.
2K Followers 2K FollowingWe focus on the small stuff so you can too: enabling the resolution revolution with high quality support films for cryo-electron microscopy. Part of @SPTLabtech
1K Followers 1K FollowingBloomberg Distinguished Professor of Structural Biophysics and Chromatin Biology at Johns Hopkins University, #Transcription #DNArepair #Chromatin #cryoEM
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206 Followers 279 FollowingPI at the University of Dundee / postdoc in MPIB/ Pre-implantation development / TFs/ Chromatin / Biochemistry / Cryo-EM / @wkobayashi.bsky.social
343 Followers 679 FollowingViews are my own PostDoc@National Institute of Environmental Health Sciences, #StructuralBiology #chromatin #TranscriptionFactor
408 Followers 251 FollowingResearcher at Univ. of Tokyo, now back to Tokyo from London. Opinions are my own. Keywords: chromatin, gene regulation, innate immunity, cryo-EM
884 Followers 943 FollowingElucidating the structural basis of biological events on chromosomes | chromatin, Xenopus egg extract, MagIC-cryo-EM | Assistant Professor at @HutchBasicSci
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2K Followers 469 FollowingRobert A. Swanson (1969) Career Development Professor of Life Sciences @MITbiology, interested in molecular machines that manage nucleic acids, views are my own
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1K Followers 414 FollowingInstitute for Quantitative Biosciences, UTokyo. We study the mechanism of transcriptional regulation in the Drosophila embryo.
2K Followers 2K FollowingWe focus on the small stuff so you can too: enabling the resolution revolution with high quality support films for cryo-electron microscopy. Part of @SPTLabtech
598 Followers 62 FollowingResearch scientist at ETH Zurich. I like taking pictures and movies of nature. Either with my camera outside or with a Titan Krios in the basement.
296 Followers 704 FollowingScientist at @NCIResearchCtr, National Cancer Institute, NIH. study #Chromatin, interested in #cryoEM, all opinions are my own.
137K Followers 23 FollowingDaily summaries of preprints posted in each bioRxiv Subject Area. Find ways to get social media alerts to individual papers at https://t.co/wrlEW1phDV
2K Followers 254 Following#Chromatin biologist/biophysicist at @NIG_idenken @SokendaiU in Japan. My career and work https://t.co/Q0x6DVCOvW
Chromatin is very dynamic and flexible, NOT regular!!!
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1K Followers 1K FollowingBloomberg Distinguished Professor of Structural Biophysics and Chromatin Biology at Johns Hopkins University, #Transcription #DNArepair #Chromatin #cryoEM
53K Followers 948 FollowingThe Journal of Cell Biology (JCB) publishes peer-reviewed research on all aspects of cellular structure and function. Est. 1955 - @RockUPress
3K Followers 2K FollowingIndustry leader providing turn-key GPU workstations/clusters, computational tools, and tailored data processing service for the cryo-EM community and beyond.
7K Followers 1 FollowingChromatin & epigenetics paper feed from #Pubmed and #Arxiv - hear it here first! Comments & suggestions welcome. Also http://t.co/0Lque7l3ZD By @mariamdemidova
14K Followers 578 FollowingPresident of the Max Planck Society since 2023 – dedicated to advancing science for the benefit of society. | @maxplanckpress
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