Core Step Prep @corestepprep

A 45-year-old man presents with fatigue and jaundice. Lab tests reveal elevated bilirubin and AST/ALT levels. Which enzyme is most likely deficient in this patient? A) UGT1A1 B) ALAS C) HMG-CoA reductase D) G6PD #CoreStepPrep #USMLE #MedStudent #MedSchool #Step1

A 5-year-old presents with developmental delay and facial dysmorphism. Genetic testing reveals a microdeletion. Which mechanism is most likely involved? A) Point mutation B) Frameshift mutation C) Chromosomal deletion D) Inversion #CoreStepPrep #USMLE #MedStudent #MedSchool

A 25-year-old male presents with fatigue and jaundice. Lab tests reveal elevated bilirubin and AST/ALT levels. What is the most likely underlying mechanism of his liver injury? A) Apoptosis B) Necrosis C) Inflammation D) Fibrosis #CoreStepPrep #USMLE #MedStudent #MedSchool #Step1

A 45-year-old man presents with fatigue and jaundice. Labs show elevated direct bilirubin and alkaline phosphatase. What is the most likely cause? A) Alcoholic liver disease B) Viral hepatitis C) Primary biliary cholangitis D) Hemochromatosis #CoreStepPrep #USMLE #MedStudent

A 45-year-old man presents with fatigue and jaundice. Lab tests show elevated AST and ALT. Which enzyme is most likely deficient? A) Glucose-6-phosphate dehydrogenase B) Pyruvate kinase C) Fructose-1,6-bisphosphatase D) Aldolase #CoreStepPrep #USMLE #MedStudent #MedSchool #Step1

A 25-year-old male presents with fatigue and pallor. Lab tests reveal microcytic anemia. Which of the following is the most likely underlying cause? A) Iron deficiency B) Thalassemia C) Chronic disease D) Lead poisoning #CoreStepPrep #USMLE #MedStudent #MedSchool #Step1

A 35-year-old man presents with muscle weakness and fatigue. Lab tests reveal elevated creatine kinase levels. Which process is primarily affected? A) Glycolysis B) Krebs cycle C) Fatty acid oxidation D) Protein synthesis #CoreStepPrep #USMLE #MedStudent #MedSchool #Step1

A 45-year-old man presents with fatigue and jaundice. Lab tests reveal elevated bilirubin and alkaline phosphatase levels. Which enzyme deficiency is most likely responsible for his condition? A) UGT1A1 B) ALP C) AST D) ALT #CoreStepPrep #USMLE #MedStudent #MedSchool #Step1

A 65-year-old man presents with chest pain and ST elevation on ECG. He has a history of hypertension and hyperlipidemia. What is the best initial management? A) Aspirin B) Beta-blocker C) Nitroglycerin D) Statin #CoreStepPrep #USMLE #MedStudent #MedSchool

A 45-year-old man presents with fatigue and muscle weakness. Lab tests reveal elevated creatine kinase levels. Which mechanism is primarily responsible for his muscle damage? A) Oxidative stress B) Apoptosis C) Necrosis D) Autophagy #CoreStepPrep #USMLE #MedStudent #MedSchool

A 45-year-old man presents with fatigue and jaundice. Lab tests reveal elevated bilirubin and alkaline phosphatase. Which enzyme is likely deficient in this patient? A) UGT1A1 B) ALP C) AST D) ALT #CoreStepPrep #USMLE #MedStudent #MedSchool #Step1

A 45-year-old man presents with fatigue and jaundice. Lab tests reveal elevated liver enzymes and bilirubin. Which enzyme is likely impaired? A) Glucokinase B) Hexokinase C) Aldose reductase D) Fructokinase #CoreStepPrep #USMLE #MedStudent #MedSchool #Step1

A 45-year-old man presents with fatigue and jaundice. Lab tests show elevated bilirubin and liver enzymes. What is the most likely underlying mechanism? A) Autoimmune destruction B) Viral infection C) Drug toxicity D) Genetic mutation #CoreStepPrep #USMLE #MedStudent #MedSchool