Dev Paudel @devomics

Bioinformagician. GreenLight Biosciences.🐊. I mess around with A's T's G's and C's all day Durham, NC Joined July 2012

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Horticulture Research @Hortres

a month ago

First tetraploid blackberry genome unveiled, aiding trait improvement! #BlackberryGenome @OxfordJournals Details: doi.org/10.1093/hr/uha…

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Horticulture Research @Hortres

3 months ago

First chromosome-scale blackberry genome assembly unveils genes for thornlessness & anthocyanins! #BlackberryGenome #PlantBreeding @OxfordJournals Details: doi.org/10.1093/hr/uha…

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Horticulture Research @Hortres

4 months ago

First chromosome-scale tetraploid blackberry genome (BL1) assembled! 88k genes, key traits mapped. Accelerates breeding. #BlackberryGenome #CropImprovement #Anthocyanins @OxfordJournals Details: doi.org/10.1093/hr/uha…

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Horticulture Research @Hortres

4 months ago

First tetraploid blackberry genome (BL1) decoded! Reveals thornlessness & anthocyanin genes for elite cultivars. #BlackberryGenomics #NutriFruitBreeding @OxfordJournals Details: doi.org/10.1093/hr/uha…

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Sebastian S. Cocioba🪄🌷 @ATinyGreenCell

4 months ago

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Bioeng Custom Lab Hardware Turn Key Genetic Design Please RT 💚

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Dev Paudel @devomics

5 months ago

Excited to share our latest work on the first chromosome-scale and haplotype-resolved genome assembly of tetraploid #blackberry. @zhanaodeng #nanopore #OpenAccess academic.oup.com/hr/article/12/…

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Omar Abudayyeh @omarabudayyeh

11 months ago

Tome announces high efficiency programmable gene insertion in non human primates with the PASTE technology. Excited that they continue to push the field forward as we continue to try and bring this technology forward for patients in one form or another

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Alejandro Montenegro @aemonten

a year ago

"Here, we report a broad survey of plasmids from hundreds of academic and industrial labs worldwide. We show that nearly half of them contained design and/or sequence errors." Trust nothing; validate everything. biorxiv.org/content/10.110…

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Kseniia Dudnyk @KDudnyk47866

a year ago

Happy to share that our work on how small set of motifs and rules explain most human promoters is published in @ScienceMagazine I am very grateful for the chance to be part of a team of amazing scientists: Donghong Cai, Chenlai Shi,@JianXuLab,@zhou_jian science.org/doi/10.1126/sc…

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Nature Biotechnology @NatureBiotech

a year ago

Prime editing deal flurry to nail down patent rights nature.com/articles/s4158…

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Zamin Iqbal @ZaminIqbal

a year ago

Mandatory reading and surprising results from Michael Hall and colleagues - much better SNP/indel calling results from latest nanopore (beating illumina), and deep learning methods really doing well. Extremely thorough work biorxiv.org/content/10.110…

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Balen Shah @ShahBalen

2 years ago

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Jonathan Gootenberg @jgooten

2 years ago

Genome editing has revolutionized the treatment of rare disease. What if we could put any change into RNA safely and reversibly? Today we (+ @omarabudayyeh ) debut PRECISE, allowing for RNA edits, deletions, and insertions from 1 to >1,000nt biorxiv.org/content/10.110… 🧵 1/x

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Niko McCarty. @NikoMcCarty

2 years ago

Biology is (still) the world's most advanced technology. Here are four interesting new papers, published yesterday. *** Two new adenine base editors. Papers: nature.com/articles/s4158… and The first base editors were known as cytosine base editors because they could substitute a…

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Jonathan Gootenberg @jgooten

2 years ago

How can we make any change in the genome, regardless of size? Today, @Tome_bio announces the acquisition of Replace Therapeutics. Together, PASTE and Replace allow edits both big and small, paving the way for new gene and cell therapies. Excited to bring these to patients!

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Omar Abudayyeh @omarabudayyeh

2 years ago

Thrilled to announce today that Tome has acquired Replace Therapeutics in a move that positions Tome to be the leader in gene integration and editing technologies. Tome now has the ability to make any sized edit, small or large, with completely distinct approaches and…

Ryan Cross the Science Boss @RLCscienceboss

2 years ago

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Jonathan Gootenberg @jgooten

2 years ago

With the the fantastic progress in recent weeks with Casgevy, it's clear a new wave of medicines will transform patient lives. @omarabudayyeh and I founded @Tome_bio to answer the question: What will the next generation of genomic medicines be? 🧵

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Omar Abudayyeh @omarabudayyeh

2 years ago

Super thrilled to see @Tome_bio come out of stealth to translate the vision of programmable gene replacement as a new editing modality for genomic medicines and cell therapy. Started this company with @jgooten to solve challenges in the gene therapy and gene editing fields. 🧵👇

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Bento Lab 🧬 @theBentoLab

2 years ago

Here’s an article about a very exciting technique for field DNA analysis: direct detection of target DNA from raw Oxford Nanopore MinION signals using trainable neural networks, running without basecalling on a $100 single-board computer. A group of researchers aiming to achieve…

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The Nobel Prize @NobelPrize

2 years ago

BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.