D.Polychronopoulos @dpolychr2
Ex @OchreBio @AstraZeneca @GenomicsEngland @imperialcollege @NCSR_Demokritos; Views my own; RT != endorsement dpolychr.github.io Cambridge, England Joined May 2016-
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Just in time for my 29th birthday today, I am so excited to present: gget v0.29.0 🎉 We added four new modules that are all about - gene-disease effects - cancer - drugs - therapeutic targets 🧵
A foundation model is used to rank drugs as potential indications and contraindications across 17,080 diseases, identifying therapeutic candidates even for diseases with no existing drugs @marinkazitnik @KexinHuang5 @jure @BenGlicksberg @girish_nadkarni nature.com/articles/s4159…
It's great to see my first paper of the PhD published in @NatureBiotech! go.nature.com/47ARizC. This describes our scRNA-seq method, scITD, for analyzing how the transcriptional states of multiple cell types are linked across patients. A few highlights from the paper:
The in-print version of the PathChat @Nature article is now available online with open access nature.com/articles/s4158… learn more about next steps and how PathChat is further being developed at @modella_ai
Interested in applying Prophet for your own functional assay? Check out the manuscript biorxiv.org/content/10.110… or grab the model itself: github.com/theislab/proph… Really excited about this new predictive approach for phenotype & drug discovery, check it out!
Does the brain change during pregnancy? You bet it does. How about doing 26 MRI scans on a single person pre-conception to 2 years post-partum. WOW! Laura Pritschet and colleagues nailed it with their new paper in @NatureNeuro. Key Points: - The authors point out that pregnancy…
Matthias @labs_mann shows first joint proteome and RNA workflow in same cell - very exciting, and lots of promises to build multimodal atlases in nearer future!
Happy that our ehrapy toolbox for the exploratory analysis of electronic health records is out today @NatureMedicine! It enables early QC&imputation at scale, visualization and downstream clustering & patient trajectory learning. nature.com/articles/s4159… github.com/theislab/ehrapy
The field of #ComputationalBiology has changed dramatically in the last few years with #GenerativeAI. I'm excited to be recording my lectures again this year, and to be teaching with the awesome @ejalm. You can find the first lecture here: youtu.be/1zZSPeKGRzw and more will…
The field of #ComputationalBiology has changed dramatically in the last few years with #GenerativeAI. I'm excited to be recording my lectures again this year, and to be teaching with the awesome @ejalm. You can find the first lecture here: youtu.be/1zZSPeKGRzw and more will… https://t.co/N2AHpxVd4j
Programming is changing so fast... I'm trying VS Code Cursor + Sonnet 3.5 instead of GitHub Copilot again and I think it's now a net win. Just empirically, over the last few days most of my "programming" is now writing English (prompting and then reviewing and editing the…
Great to see our research "Genetic factors associated with reasons for clinical trial stoppage" finally out in Nature Genetics nature.com/articles/s4158…
𝐟𝐥𝐞𝐱𝐲𝐧𝐞𝐬𝐢𝐬, our new deep learning-based data integration tool for multi-omics. 1000s of deep learning workflows are available. Paper: biorxiv.org/content/10.110… Code: github.com/BIMSBbioinfo/f… Benchmarks: bimsbstatic.mdc-berlin.de/akalin/buyar/f… Tutorial/docs: bimsbstatic.mdc-berlin.de/akalin/buyar/f…
Published today! We found that cancer cells adapting to drug treatments don't simply switch from a sensitive to resistant state; instead there's a ‘resistance continuum’ of resistant phenotypes with epigenetically reprogrammed states. 🧵⬇️ nature.com/articles/s4158… @Gustavo_SFranca
What I’m reading this week in single cell omics, generative AI in genomics and medicine, microbial genomics, bioinformatics software, … 🧬🖥️🧵
How to link single-cell diversity and the emergence and maintenance of robust multicellular processes in developed tissues? 🤔 What can we learn about multicellular coordination in tissues from single-cell omics data? Read about our view: arxiv.org/abs/2403.06753
Opportunities and tradeoffs in single-cell transcriptomic technologies buff.ly/47NcBgv
With six approved drugs, siRNA is now an established therapeutic modality poised for expansion go.nature.com/49tcrf8 rdcu.be/dAsb2
**Is single-cell data integration a solved problem? ** Lots of great methods, but still not quite yet! Specifically, Check Dataset Imbalance! 🎉 Excited to announce that our study on dataset imbalances in single-cell analysis just hit Nature Biotechnology (@NatureBiotech)! 🎉…
Are you looking to apply Large Language Models to biomedical questions? You may want to take a look at our new framework (biochatter.org) and the updated preprint (arxiv.org/abs/2305.06488). 🧵👇
Major Cell2Sentence update 🎉🔬! We’ve been thrilled to see the attention Cell2Sentence has received from the single-cell community. Now, we’re excited to release our first update of Cell2Sentence (C2S) - a framework to leverage LLMs to train foundational single-cell models,…
Manolis Kellis @manoliskellis
29K Followers 4K Following Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstitute
Veera Rajagopal @doctorveera
19K Followers 4K Following 🇮🇳 MBBS, MD, 🇩🇰 PhD | 🧬 Scientist @ 🇺🇸 Regeneron | Translating genetic insights into life-saving medicines | thoughts @ https://t.co/dTItNQy2BX
Akis Papantonis @AkisPapantonis
4K Followers 947 Following Professor for Translational Epigenetics & Genome Architecture, University Medical Centre Göttingen, Germany …oftentimes aspiring fiction writer.
Evangelia Petsalaki @e_petsalaki
2K Followers 549 Following Group Leader at EMBL-EBI, interested in context specific regulation of human cell signalling. bsky:epetsalaki
Antoine Hocher @antoine_hocher
546 Followers 650 Following Group leader, MIMIC Lab Departments of Genetics, University of Cambridge
Helena Cocheme @CochemeLab
984 Followers 1K Following Group Head @MRC_LMS @ImperialCollege Lab studying #redox signalling, metabolism, diets and #ageing in #Drosophila
Florian Markowetz @markowetzlab
4K Followers 2K Following Computational Oncology at Cambridge | chromosomal instability | genomes and images | selfish about reproducibility | useless models | all fox, no hedgehog
Christoforos Nikolaou @guilderstern
1K Followers 655 Following Computational Biologist, Researcher at @BSRC_Fleming, author and amateur sports journalist. "What difference can you make, a single man in all this madness?"
Alejandro Montenegro @aemonten
9K Followers 7K Following Molecular Biologist, PhD丨Chief Editor CSH Protocols & Head of Integrity in Publishing — @CSHL丨Scientific Chair @molbiosystems丨Central Dogma Police丨Chilean 🇨🇱
Qualytics @QualyticsData
91 Followers 516 Following Qualytics is the complete solution to instill trust and confidence in your enterprise data ecosystem. Do you trust your data? Let us give you #DataConfidence.
Losearson @Losearsonosd0c
77 Followers 1K Following
Vishnu Dileep @vishnudileep200
258 Followers 260 Following Assistant Professor at Baylor College of Medicine, studying the brain through the lens of genomics.
Smooshair @SmooshairQdW
100 Followers 3K Following
Teashey @TeasheyKiP
11 Followers 1K Following
Jonathan Mitchel @J_E_Mitchel
237 Followers 483 Following PhD candidate at Harvard-MIT HST @mit_hst. Studying cells with computers. Computational biology | Single-cell genomics | Coffee |
us_Kayla_ @UsKayla19084
2 Followers 117 Following 🎭 Theatre lover & drama enthusiast | Wine connoisseur & foodie | Savoring the flavors of life, both on stage and on plate 🍷🎭
Addison @Addison6222830
4 Followers 108 Following 📖 Bookworm & literary lover | Tea addict & cozy enthusiast | Escaping reality one page at a time 📚☕️
Darko Medin @MedinDarko
813 Followers 925 Following AI Creator. Senior Biostatistics & AI Constultant. Data Scientist/Biology AI expert, Researcher. R and Python programmer. Contractor.
Isabel @isabel_queal_
329 Followers 3K Following
Lukas B Krone @LBKrone
451 Followers 352 Following Sleep(ing) neuroscientist and somnologist 💤🪰🐭😴👨⚕️ dreaming to become an astronaut 👨🚀 🚀🌍🌖 @wellcometrust & @ExeterCollegeOx research fellow @OxNeuro
Caroline @guest_caroline6
261 Followers 3K Following
Ankur Parikh @ank_parikh
3K Followers 4K Following Staff Research Scientist at Google DeepMind. Former adjunct assistant prof at @NYU_Courant. PhD at @mldcmu. ML for Bio/Chem (Prev. NLP). All opinions my own.
Constantine Tzouanas @constantine_sci
353 Followers 713 Following Making every day in lab as unique as every single cell | @shaleklab | Harvard-MIT @mit_hst | @HertzFoundation Fellow | @NSFGRFP Fellow
Imogen @soughm60527
269 Followers 5K Following See the world on the road, and get to know yourself on the way!
Hao Yin @HaoYin20
12K Followers 11K Following Cardiovascular biologist @WesternU PhD @UCalgary BSc @PKU1898 Views are my own Developmental Biology Social media editor @Dev_Bio_Journal Just call me Hao (How)
Whitney @Smeetea196871
231 Followers 5K Following See the world on the road, and get to know yourself on the way!
Elenor @sieverelenor19
243 Followers 3K Following
Dwayne @satodasef94986
272 Followers 5K Following See the world on the road, and get to know yourself on the way!
Kasia Kędzierska �... @kzkedzierska
700 Followers 513 Following find me on blue sky https://t.co/eDJA8HZonf
Laura Jiménez Gracia @ljimenezgracia
737 Followers 819 Following PostDoc at Single-cell Genomics - @hoheyn Lab, @cnag_eu | Teaching | Bioinformatics & Biomedicine | Food lover, always learning & enjoying outdoors!
Sharon @baugussharon42
290 Followers 3K Following
Olin @seeteele71403
286 Followers 5K Following See the world on the road, and get to know yourself on the way!
Flora @Gasasyt142786
254 Followers 5K Following See the world on the road, and get to know yourself on the way!
Deborah @z_deborah81
260 Followers 3K Following
Helen @frias57helen
361 Followers 3K Following
Rebellious @Testea372640
260 Followers 5K Following See the world on the road, and get to know yourself on the way!
TransCure bioServices @_TransCure
296 Followers 2K Following The only #CRO specialized in #HumanizedMice #MouseModels for #Oncology #ImmunoOncology #AML #InflammatoryDiseases #IBD #InfectiousDiseases #HIV studies
Russell Zhang Kunes @russell_kunes
524 Followers 2K Following Now a quantitative researcher at a hedge fund. Previously worked in computational biology & bioinformatics.
Thomas Walle @science_wallet
752 Followers 951 Following trying to help patients by understanding their individual immune status 🇪🇺 https://t.co/fvbzNRmYGZ…
Elizabeth @elizabe83426510
486 Followers 3K Following
David van Dijk @david_van_dijk
5K Followers 4K Following Assistant Professor @Yale @YaleMed @YaleCSDept | ML/AI comp bio
Austin Argentieri @austinargen
391 Followers 178 Following Using big data to study aging and chronic disease risk @broadinstitute and @MGHMedicine. Previous postdoctoral researcher @bdi_oxford.
Therese @therese_ourada5
274 Followers 3K Following
Ke Yuan @keyuan1
378 Followers 933 Following Senior Lecturer @GlasgowCS @UofGlasgow | Machine Learning & Computational Biology
MAIDEN @MAIDEN_MAFLD
8K Followers 7K Following Metabolic Dysfunction-Associated Fatty Liver Disease Consortium (MAIDEN) official account.
Ana Viñuela @anavinuela
1K Followers 1K Following Not here anymore. Mastodon: @[email protected] Bluesky: @anavinuela.bsky.social
Hussain Abbas @HussainAbbas_HK
117 Followers 215 Following General Surgery Registrar | HPB and Liver Transplant | Normothermic machine perfusion research | Academic Clinical Lecturer, University of Oxford | Views my own
Will Quince @willquince
23K Followers 3K Following Commercial Property Solicitor. Transport East Chair. Army Reservist. Former MP and UK Government Minister.
Jamie Cartland @jamieconduit
251 Followers 815 Following Co-founder @ Conduit. Imagining a future where we can deploy global computational expertise to our toughest biopharma challenges. Also try music (Clouded on SC)
Mikaela Koutrouli @MKoutrouli
475 Followers 315 Following PostDoc @genentech in the group of @MarioniLab | Interested in single-cells, deep learning, networks | Core member @scverse_team | https://t.co/wNWP4SbLVw
Qian Cheng @sgqcheng
600 Followers 535 Following Senior Editor @NatureComms. PhD @Cambridge_Uni. Views my own.
Anshul Kundaje (anshu... @anshulkundaje
26K Followers 3K Following Federally funded academic research is the innovation engine of the US economy. Reform is welcome. Destruction will have long term consequences.
Lior Pachter @lpachter
47K Followers 2K Following Bren Professor of Computational Biology @caltech. Blog at https://t.co/FFQzhEsmhi. Tweets represent my views, not my employer's. #methodsmatter
Manolis Kellis @manoliskellis
29K Followers 4K Following Dissecting disease mechanism. Single-cell, Epigenomics, Regulatory Genomics, Disease Genetics, Brain, Cancer, Metabolism. @MIT Prof, @MIT_CSAIL, @BroadInstitute
Fabian Theis @fabian_theis
35K Followers 426 Following Computational biologist @HelmholtzMunich, prof @TU_Muenchen & associate PI @sangerinstitute. Dad of 4 and mountain lover. Department news, see @CompHealthMuc
Ming "Tommy" Tang @tangming2005
41K Followers 2K Following Director of bioinformatics at AstraZeneca. YouTube at chatomics. On my way to helping 1 million people learn bioinformatics. Also talks about leadership.
Iannis Aifantis @iannisaifantis1
10K Followers 1K Following Cancer & Immunology Research. Professor & Chair, @NYUGSOM_Path @nyugrossman. All opinions are my own only. Visit me also on @instagram and @LinkedIn.
Andrej Karpathy @karpathy
1.4M Followers 1K Following Building @EurekaLabsAI. Previously Director of AI @ Tesla, founding team @ OpenAI, CS231n/PhD @ Stanford. I like to train large deep neural nets.
Veera Rajagopal @doctorveera
19K Followers 4K Following 🇮🇳 MBBS, MD, 🇩🇰 PhD | 🧬 Scientist @ 🇺🇸 Regeneron | Translating genetic insights into life-saving medicines | thoughts @ https://t.co/dTItNQy2BX
Ewan Birney @ewanbirney
48K Followers 2K Following Deputy Director General of EMBL, Director of EMBL-EBI. I have an insatiable love of biology. @[email protected]. I also work with ONT, Dovetail + GeL.
Akis Papantonis @AkisPapantonis
4K Followers 947 Following Professor for Translational Epigenetics & Genome Architecture, University Medical Centre Göttingen, Germany …oftentimes aspiring fiction writer.
Evangelia Petsalaki @e_petsalaki
2K Followers 549 Following Group Leader at EMBL-EBI, interested in context specific regulation of human cell signalling. bsky:epetsalaki
Antoine Hocher @antoine_hocher
546 Followers 650 Following Group leader, MIMIC Lab Departments of Genetics, University of Cambridge
Florian Markowetz @markowetzlab
4K Followers 2K Following Computational Oncology at Cambridge | chromosomal instability | genomes and images | selfish about reproducibility | useless models | all fox, no hedgehog
dana_peer @dana_peer
14K Followers 158 Following
Eytan Ruppin, MD, PhD @EytanRuppin
5K Followers 1K Following Computational precision oncology researcher | Chess & bridge enthusiast ♟️🃏 Ethnic music lover 🎵 Seinfeld fanatic 📺 Sci-fi aficionado 🛸 | All views my own
Christoforos Nikolaou @guilderstern
1K Followers 655 Following Computational Biologist, Researcher at @BSRC_Fleming, author and amateur sports journalist. "What difference can you make, a single man in all this madness?"
Prof. Nikolai Slavov @slavov_n
20K Followers 250 Following Mentor, scientist & engineer. Director of @ParallelSqTech. Having fun in @SlavovLab with single-cell proteomics & ribosomes. Organizer of @SCP_meeting
Vince Buffalo @vsbuffalo
16K Followers 3K Following Scientist at IDM. ♥s epidemiology, running, probability+statistics, 🦀, fly fishing, backpacking. Author of book Bioinformatics Data Skills. All views my own.
Defiant L’s @DefiantLs
1.6M Followers 169 Following Exposing hypocrisy, one day at a time. | DM submissions
Mohammed AlQuraishi @MoAlQuraishi
11K Followers 350 Following MLing biomolecules en route to structural systems biology. Asst Prof of Systems Biology and CS @Columbia. Prev. @Harvard SysBio; @Stanford Genetics, Stats.
Laura Luebbert, PhD @NeuroLuebbert
4K Followers 1K Following genetics, compbio & viruses · @broadinstitute @Harvard ←@Caltech · Author of #gget (the software not the coffee bar, unfortunately)
Lorenzo Righetto @LorenzoRighett7
1K Followers 1K Following Senior editor Nature Health (digital medicine, computational health) @lorenzorighetto.bsky.social
Lappalainen Lab @tuuliel_lab
6K Followers 584 Following Functional human genomics @ KTH, SciLifeLab, NY Genome Center. Pro science here, more fun stuff fun at @tuuliel. Mastodon [email protected]
Mira Murati @miramurati
366K Followers 572 Following Now building @thinkymachines. Previously CTO @OpenAI
Jonathan Mitchel @J_E_Mitchel
237 Followers 483 Following PhD candidate at Harvard-MIT HST @mit_hst. Studying cells with computers. Computational biology | Single-cell genomics | Coffee |
Elon Musk @elonmusk
225.5M Followers 1K Following
Emily G. Jacobs 🦋 ... @emilyjacobs
3K Followers 722 Following Director Ann S. Bowers WBHI @Bowers_WBHI | Prof @UCSantaBarbara | Using neuroscience tools to shine a floodlight on women’s brain health https://t.co/00KWMr6tbG
Neuralink @neuralink
1.7M Followers 1 Following Creating a general-purpose, high-bandwidth interface to the brain
Jonathan Cairns @jonathancairns
2K Followers 824 Following Data wizard, biostatistician, occasional comedian, unexpected series champion of Only Connect. He/him. Views my own.
Serafim Batzoglou @s_batzoglou
3K Followers 776 Following Genomics-computation-ML-biotech-foundations of math-philosophy of mind; CDO @seer_bio; former prof @StanfordAILab; cofounder @dnanexus; opinions entirely my own
Alex Colville @AlexJColville
4K Followers 459 Following General Partner at @age1vc extending healthy lifespan. PhD alum of @Thomas_Rando @stanfordmed
Altos Labs @altos_labs
22K Followers 26 Following Altos Labs is a biotechnology company dedicated to unraveling the deep biology of cell rejuvenation to reverse disease.
Maria Brbic @mariabrbic
2K Followers 223 Following Assistant Professor of #computerscience and #lifesciences at @EPFL @ICepfl @epflSV Previously @Stanford #AI #compbio
Peterhouse Cambridge @Peterhouse_Cam
5K Followers 321 Following Tweeting the latest news from Peterhouse as well as Petrean news and events.
Lukas B Krone @LBKrone
451 Followers 352 Following Sleep(ing) neuroscientist and somnologist 💤🪰🐭😴👨⚕️ dreaming to become an astronaut 👨🚀 🚀🌍🌖 @wellcometrust & @ExeterCollegeOx research fellow @OxNeuro
Ankur Parikh @ank_parikh
3K Followers 4K Following Staff Research Scientist at Google DeepMind. Former adjunct assistant prof at @NYU_Courant. PhD at @mldcmu. ML for Bio/Chem (Prev. NLP). All opinions my own.
Patrick Schwab @schwabpa
7K Followers 2K Following ML for Drug Discovery and Health. Posts are personal opinions.
Bo Wang @BoWang87
13K Followers 2K Following SVP and Head of Biomedical AI @Xaira_Thera; Associate Prof @UofT; Chief AI Officer @UHN; former PHD, CS @Stanford; opinions my own. #AI #healthcare #biology
Brad Loncar @bradloncar
78K Followers 366 Following #Biotech, Founder of @BiotechTV, KC native, @univmiami hurricane.🧬🙌
Shalek Lab @shaleklab
3K Followers 122 Following Alex K. Shalek Lab @MIT/@ragoninstitute/@broadinstitute/@harvardmed/@MGH_RI. Genomics, immunology, systems biology.
Constantine Tzouanas @constantine_sci
353 Followers 713 Following Making every day in lab as unique as every single cell | @shaleklab | Harvard-MIT @mit_hst | @HertzFoundation Fellow | @NSFGRFP Fellow
nik t. hatziefstathio... @nikthehat
39K Followers 2K Following 〈🇺🇸〉Chasing the Untold Stories + Hunting America’s Most Wanted with @DogBountyHunter • Advanced Machine Learning & Artificial Intelligence at Harvard
Hao Yin @HaoYin20
12K Followers 11K Following Cardiovascular biologist @WesternU PhD @UCalgary BSc @PKU1898 Views are my own Developmental Biology Social media editor @Dev_Bio_Journal Just call me Hao (How)
Emily Riederer @EmilyRiederer
7K Followers 5K Following Three R's in my last name, but it's not enough #rstats for me! Sr Analytics Manager at Capital One Math/Stats at UNC CH https://t.co/4stm3KVbBX
Richard Sever @cshperspectives
20K Followers 1K Following Chief Science and Strategy Officer, openRxiv. bioRxiv & medRxiv Co-Founder
Paul Harrison @paulfh... @paulfharrison
662 Followers 218 Following It is time to go. @paulfharrison.bsky.social @[email protected]
Eric Lubeck @eric_lubeck
262 Followers 968 Following
🔥 Matt Dancho (Bus... @mdancho84
85K Followers 482 Following Future Is Generative AI + Data Science | Helping My Students Become Generative AI Data Scientists & AI Engineers ($200,000+ career) 👇
Generate:Biomedicines @generate_biomed
6K Followers 137 Following As pioneers in generative biology, we're revolutionizing the way biotherapeutics are discovered and developed.
Kevin K. Yang 楊凱�... @KevinKaichuang
21K Followers 6K Following Principal Researcher in BioML @MSFTResearch (@MSRNE). He/him/他. 🇹🇼
Biotechnology Innovat... @IAmBiotech
106K Followers 6K Following I Am Biotech is where biotech professionals and enthusiasts can come together and discuss the promise of biotech innovation. #Biotech
Biotech Hangout @BiotechCH
15K Followers 549 Following Weekly discussion of biotech news w/ @daphnezohar @bradloncar Josh Schimmer @timopler @LifeSciVC, @cngarabedian, & other biotech insiders
PureTech @PureTechH
4K Followers 1K Following We're a hub-and-spoke biotherapeutics company dedicated to giving life to science and transforming innovation into value for patients and shareholders
Robert Nelsen @rtnarch
25K Followers 570 Following Company founder and venture capitalist focused on disruptive innovation, esp. biotechnology. Active angel in tech. Fierce Optimist.
LomvardasLab @LomvardasLab
2K Followers 1K Following Laboratory of Stavros Lomvardas, PhD Zuckerman Mind Brain Behavior Institute | Jerome Greene Science Ctr https://t.co/OPR19GE561
Hongyu Ren @ren_hongyu
23K Followers 691 Following research @meta superintelligence. CS PhD @stanford. prev @openai, led the development of o3-mini and o1-mini.
Camilo Ruiz @_camiloruiz
862 Followers 2K Following PhD @Stanford with @jure | AI for Biology | Previously @MIT, @Gates_Cambridge, @Cambridge_Uni
Ang Cui, Ph.D. @AngCuiPhD
972 Followers 98 Following Assistant Professor at Harvard University. Immunology & Big Data. Head of Systems Immunology Research Laboratory @harvardmed @broadinstitute
PostCheetah @PostCheetah
4K Followers 59 Following Combining AI + Google Metrics to Bring Your SEO Into Overdrive.
Michael Galkin @michael_galkin
7K Followers 332 Following Senior Research Scientist @GoogleAI. Prev: @Intel, Postdoc @Mila_Quebec & McGill. Graph Learning & LLMs. Grandmaster of 80's music (according to Spotify)
Arjun Krishnan @compbiologist
1K Followers 281 Following ML & data-driven discovery; Complex traits & diseases; Data reuse & open science. Associate Professor | Group leader @KrishnanLab | @compbiologist everywhere
Kasia Kędzierska �... @kzkedzierska
700 Followers 513 Following find me on blue sky https://t.co/eDJA8HZonfTrends for United States
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