Dean Singleton @drdeansingleton
Cancer Researcher @ACSRC_UoA @AucklandUni Auckland, New Zealand Joined October 2016-
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Following78
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Dean Singleton retweeted
In a new Review now live online, @drdeansingleton, Andrew Macann & William Wilson discuss 'Therapeutic targeting of the hypoxic tumour microenvironment': nature.com/articles/s4157… @ACSRC_UoA #radonc #caxtx #camicroenv
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Dean Singleton retweeted
Wow 😲 Incredible to have a tireless contributor to cancer research, medicinal chemistry and past ACSRC Director Distinguished Professor William A. Denny (or Bill as most of us know him) made a Knight Companion of the New Zealand Order of Merit. 🥳🎺Congratulations Sir Bill! 🎺🥳
Dean Singleton retweeted
The origin of this story is one of my colleagues asked for an immunity explainer, and I said, "GOD NO, have you any idea how complicated immunology is, that would kill me," but then I realized that I am already dead inside, and wrote the piece. theatlantic.com/health/archive…
Dean Singleton retweeted
A new paper from @georg_e_winter and @CrisMayorRuiz performed chemical profiling in hyponeddylated cells coupled with multi-omics target deconvolution to identify molecular glue degraders of cyclin K. nature.com/articles/s4158…
Dean Singleton retweeted
Our cancer special issue is out today! cell.com/molecular-cell…
Dean Singleton retweeted
1/ Our latest work was just published in @NatureMedicine! Congratulations to first author Super-Star @BraunMDPhD and to all authors. #CathyWu #SachetShukla @LabSignoretti @VanAllenLab #FreemanLab #SharpeLab @DanaFarberNews @DanaFarber #kcsm #KidneyCancer doi.org/10.1038/s41591…
New work published today detailing our identification of pyruvate as an important mechanism of resistance to anticancer drugs that target glutamine metabolism bmccancer.biomedcentral.com/articles/10.11…
Dean Singleton retweeted
We may be apart for #MayMorning this year, but thanks to @MagdCollChoir we can still celebrate together. Thank you @magdalenoxford for making today so special, 500 years after the tradition first began, with a virtual May Morning. Watch here: youtu.be/CEBsmxAfGiY
Epic presentation 👍 TWIT101 Twitter at the ACSRC for beginners
Final planning meeting! #ACSRC2020 @ACSRC_UoA
Dean Singleton retweeted
Researchers used the “longevity signatures,” including up-regulation of oxidative phosphorylation and drug metabolism, to help identify drugs that might extend lifespan. (via @Cell_Metabolism) cell.com/cell-metabolis…
Dean Singleton retweeted
Next-generation characterization of the Cancer Cell Line Encyclopedia fal.cn/ALQb via @Nature
Dean Singleton retweeted
The landscape of cancer cell line metabolism fal.cn/ALQw via @NatureMedicine
Dean Singleton retweeted
Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration fal.cn/SFqS via @NatureComms
Dean Singleton retweeted
Specific CD8 T cell states may indicate response to immune checkpoint therapy for #melanoma fal.cn/So7H
Dean Singleton retweeted
Researchers identify a gene expression pattern in #melanoma that can help indicate which patients will be resistant to #immunotherapy, and devise an approach to counter this resistance fal.cn/SowD
Dean Singleton retweeted
Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes fal.cn/STgJ via @NatureMedicine
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