Erin Thompson @ernpossible
Biologist @Octantbio, coffee snob, injured runner-turned-cyclist Bay Area Joined July 2015-
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Very cool, especially re: structure based drug design! Congrats Keedy lab, again proving RT is best 🔥🔥
Very cool, especially re: structure based drug design! Congrats Keedy lab, again proving RT is best 🔥🔥
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Have you ever wanted to make a library that includes indels? Well now you can! Super excited this is finally out, congrats @willowcoyote
Have you ever wanted to make a library that includes indels? Well now you can! Super excited this is finally out, congrats @willowcoyote
Erin Thompson retweeted
Happy to share the @biorxivpreprint for my first bit of work w/ @aliceyting. Together with @heegwangroh, we built a simple and versatile single-component luminescent biosensor for detecting the SARS-CoV-2 spike protein. biorxiv.org/content/10.110…
Have to give a special shout out to my old labmate @willowcoyote, presenting on a library generation method, DIMPLE, to address the difficulty in making systematic indel libraries. He recently started as a Hannah Gray Fellow, go check out his work! #VariantEffect22
Have to give a special shout out to my old labmate @willowcoyote, presenting on a library generation method, DIMPLE, to address the difficulty in making systematic indel libraries. He recently started as a Hannah Gray Fellow, go check out his work! #VariantEffect22
.@LindorffLarsen on disentangling stability-activity-folding contributions of variants that are important for fxn and using this data to predict effect mechanism for disease variants #VariantEffect22
.@LindorffLarsen on disentangling stability-activity-folding contributions of variants that are important for fxn and using this data to predict effect mechanism for disease variants #VariantEffect22
Ok fellow MAVE/DMS enthusiasts, I think the time has come that we standardize heat map coloring. Personally like blue for gain of function, red for loss of function (reasoning red = bad in my mind) but could be persuaded otherwise @varianteffects #VariantEffect22
Erin Thompson retweeted
🚨PREPRINT ALERT!!!🚨 I’m beyond excited to finally share this work, where we demonstrated the use of temperature-jump as a perturbation for time-resolved crystallography, specifically to study protein dynamics! 🔥💎 biorxiv.org/content/10.110… 🧵 1/32
Excited to be here at #VariantEffect22 with my other @OctantBio colleagues. A great kickoff to the conference hearing about how clinical data + functional data can be used to improve variant interpretation @conor_j_howard @diane_dickel @srikosuri @n_s_abell
Excited to be here at #VariantEffect22 with my other @OctantBio colleagues. A great kickoff to the conference hearing about how clinical data + functional data can be used to improve variant interpretation @conor_j_howard @diane_dickel @srikosuri @n_s_abell
Erin Thompson retweeted
Where are allosteric hotspots located in a protein? What properties differentiate such hotspots from other residues? We combine deep mutational scanning of four homologs with machine learning to reveal molecular rules governing allosteric hotspots. biorxiv.org/content/10.110…
Erin Thompson retweeted
Very happy to announce the close of @OctantBio’s $80M Series B, led by Catalio, along with @a16z, @8vc, @bmsnews. Looking forward to working with @srikosuri, @rhomsany & their team to further develop Octant's innovative synthetic biology platform fiercebiotech.com/biotech/wild-w…
Erin Thompson retweeted
Lots of @OctantBio news to share today, including our Series B led by @CatalioCapital @georgecpetro. Immensely thankful for the support, including @a16z @bmsnews @fiftyyears @GaingelsVC @8vc Allen & Company LLC and many more amazing investors and angels, too long a list for here
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