Gregg Fonarow MD @gcfmd
Los Angeles, CA Joined December 2012-
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Advancing HF stages were associated with increasing risk mortality Development and implementation of early screening and targeted interventions are urgently needed to reduce HF burdens in China Prognostic implications of HF stages among Chinese... sciencedirect.com/science/articl…
Heart Failure Mortality Higher Now Than in 1999 dlvr.it/T63y37
We have the tools & know-how to bend this curve ⤵️. ✅ and manage #BloodPressure ✅ and manage blood glucose 🚭 discourage #smoking 🚶♀️ encourage & empower active living Begin preventive screenings and treatments early in life. @AmJPrevMed @amjhypertension @AMJPublicHealth
We have the tools & know-how to bend this curve ⤵️. ✅ and manage #BloodPressure ✅ and manage blood glucose 🚭 discourage #smoking 🚶♀️ encourage & empower active living Begin preventive screenings and treatments early in life. @AmJPrevMed @amjhypertension @AMJPublicHealth
“Recent data suggest plateaus or reversals after long-standing declines in cardiovascular mortality, particularly for HF-related mortality” @JAMACardio #Cardiotwitter Read more👇 healio.com/news/cardiolog…
US heart failure deaths in 2021 reached levels not seen since 1999 healio.com/news/cardiolog… @JAMACardio @FudimMarat @ASayedMD @JavedButler1
How have HF mortality rates changed from 1999-2021 in the US? From 1999-2012 ↘ : Decline by ~25% From 2012-2021 ↗ Reversals that have now undone ALL initial declines. 🚨HF mortality in 2021 > HF mortality in 1999 🚨 jamanetwork.com/journals/jamac… @FudimMarat @ASayedMD @HFSA
Analysis shows that initial declines in HF-related mortality from 1999 to 2012 have been entirely undone by subsequent reversals from 2012 to 2021, meaning that contemporary HF mortality rates are higher than in 1999. ja.ma/3UcwM23
HFrEF ↘️↘️↘️median survival 7-18 years GDMT ↗️↗️↗️ median survival: ✅ ARNI 2-3 yrs (1-2 yrs vs ACEI or ARB) ✅ BB 3-4 yrs ✅ MRA 2-3 yrs ✅ SGLTi 1-2 yrs Clinical benefits non-overlapping, incremental, additive Quadruple >>>triple>>>double Fast >>>>slow Now>>>later
Decline in heart failure deaths has been undone, led by people under 45 statnews.com/2024/04/24/hea… via @statnews @JAMACardio @NMHheartdoc @FudimMarat @JavedButler1 @ASayedMD
What now❓ ⏫ Interventions to prevent HF ⏫ Interventions to treat HF ⏫ Wider & equitable access (potential role for remote patient care?) ❓ Revisit potentially problematic policies 🔬 Revisit impact of pandemic on healthcare
How have HF mortality rates changed from 1999-2021 in the US❓ From 1999-2012📉: Decline by ~25% From 2012-2021📈: Reversals that have now undone ALL initial declines. Result: HF mortality in 2021 > HF mortality in 1999 ‼️ Link to our work @JAMACardio : jamanetwork.com/journals/jamac…
Why❓ Potential culprits: 1⃣ ⏫ metabolic disease ➡️ ⏫ HF prevalence 2⃣ 🚫care access ➡️ 🚫GDMT ➡️ ⏫ HF mortality 3⃣ HRRP ➡️ bad incentives ➡️ ⏫ HF mortality 4⃣COVID (exacerbating) ➡️ healthcare interruptions +/- 🫀involvement ➡️ ⏫ HF prevalence/mortality
Effects of #GDMT across Kidney Function Spectrum ✅ #BB: consistent benefit to eGFR 30 ✅ #ARNI: consistent benefit to eGFR 30 ✅ #SGLT2i: consistent benefit to eGFR 20 ❌ #SteroidalMRA: ↓ benefit & worse safety at lower eGFR New strategies to block MR axis in HF & CKD needed!
Impressive data on HFrEF: Although 82% of patients are eligible for quadruple therapy at discharge, only 15% actually receive it. This underutilization could significantly impact patient outcomes. @gcfmd @JACCJournals @ACCinTouch @CircAHA @ESCardioNews jacc.org/doi/10.1016/j.…
⚠️Eligibility and Projected Benefits of Rapid Initiation of Quadruple Medical 💊 for Newly Diagnosed #HF 👥 33036 🇺🇸newly diagnosed with HFrEF 👉82% were eligible for4️⃣💊, 👉93% were eligible for 3️⃣💊 ⏰ 2021- 2023, of 👥 eligible for 4️⃣💊 ▶️15.3% were prescribed 4️⃣💊 ▶️41.5%…
Dr. Martha Gulati ♥.. @DrMarthaGulati
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30 Followers 80 FollowingFusion Prog Guy @FusionProgGuy
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148K Followers 2K Following Official American College of Cardiology account. Join us to transform cardiovascular care & improve heart health. Find us: @JACCJournals @CardiologyMichelle Kittleson MD.. @MKIttlesonMD
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291 Followers 17 FollowingMarat Fudim, MD MHS @FudimMarat
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651 Followers 567 Following Stanford heart failure, health services researcherNeal Dixit, MD @NealDixit
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148 Followers 316 FollowingAdvanced Registration discount for #AthleticHeart24 ends today! Register now to save $ & grab one of the limited remaining in-person seats Virtual option also available 🔗 acc.org/athleticheart2…
🗓️ Save the date for ACC Care of the Athletic Heart! 💥Hybrid at Heart House (DC) and Virtual ⭐️ All-star sports cardiology educators 👀 Watch here for details & use link below to sign up for updates, especially if you want to nab an in-person slot! acc.org/athleticheart2…
Phenomenal discussions @JAMACardio - new directions, new efficiencies, committed growth; fulfilling our vision as a leading voice for best CV clinical science, actionable clinical summaries, & top-of-mind paradigms in Cardiology. Grateful for your support 🙏🏽 @JAMA_current
Incredible meeting with the editors & editorial board of @JAMACardio led by Bob Bonow @NorthwesternMed Energized & dedicated team committed to science & medical publishing in cardiology- proud to partner with them!
Incredible meeting with the editors & editorial board of @JAMACardio led by Bob Bonow @NorthwesternMed Energized & dedicated team committed to science & medical publishing in cardiology- proud to partner with them!
#HeartFailureDays #HeartFailureWeek Know it 🧠 Recognize it 🔍 Treat it 💊 💉 🏥 “We need to find them” #Findme @gcfmd @HFA_President @JJheart_doc @AndrewJSauer @DrMarthaGulati @JavedButler1 @AndrewJSauer @RFE_Pedretti @pumpinghearts @DrRajivsankar @gbiondizoccai @escardio
We are delighted to announce the release of our film Detect the Undetected: Find Me. This compelling film showcases real-life stories of three remarkable couples who share their journey of recognising heart failure symptoms, urging their loved one to seek medical attention,…
Heart failure deaths rising in people under 45 jamanetwork.com/journals/jamac…
Thank you Dr. Al-Lamee @rallamee for an absolutely incredible Cardiology Ground Rounds at UCLA!
Amazing grand rounds @UCLAHealth from world renowned ORBITA trialist Dr. Rasha Al-Lamee discussing the importance of placebo controlled trials for medical procedures!!! Thank you so much for this fantastic session! @rallamee @uclaCVfellows @kewatson @datsunian #WIC #bruinhearts
Heart Failure Mortality Higher Now Than in 1999 dlvr.it/T63y37
Congrats to @ASayedMD for leading this work around how HF mortality has changed in the last 2 decades published in @JAMACardio - thank you for inviting me to contribute
How have HF mortality rates changed from 1999-2021 in the US❓ From 1999-2012📉: Decline by ~25% From 2012-2021📈: Reversals that have now undone ALL initial declines. Result: HF mortality in 2021 > HF mortality in 1999 ‼️ Link to our work @JAMACardio : jamanetwork.com/journals/jamac…
Amazing grand rounds @UCLAHealth from world renowned ORBITA trialist Dr. Rasha Al-Lamee discussing the importance of placebo controlled trials for medical procedures!!! Thank you so much for this fantastic session! @rallamee @uclaCVfellows @kewatson @datsunian #WIC #bruinhearts
It was a privilege to present Norman Stockbridge with the 2024 HFC Lifetime Achievement Award for contributions to regulatory science, advocacy for the community without walls,and his disciplined integrity that has improved many pts. via CV and renal therapies.@HeartBobH
What a humble privilege to promote the relentless mission of the @AHAScience @HeartNews @American_Heart @NancyatHeart @dmljmd @HeartBobH @NMCardioVasc @NorthwesternMed
1/ The Centennial Presidential Advisory, written by 14 AHA presidents, looks back at 100 years of cardiovascular progress and sets the stage for a Second Century of lifesaving work. @NMHheartdoc reflects on AHA’s historic journey. #AHABoldHearts
@gcfmd @JAMACardio @FudimMarat @ASayedMD @JavedButler1 Unbelievable, and despite the arrival of SGLT2i and Entresto! Is this due to Covid19, lack of prescribing GDMT for HFrEF & HFpEF (which is criminal given the data), or other?
A tour de force @UCLAHealth ♥️ GR by one of the most innovative clinical trialists in IC today @rallamee whose work has evolved/challenged how we assess & treat angina. An incredible narration of the journey/controversies of #ORBITA & what is in store from this 🔥 group!! 🙏
Life update: proud to say that I’ll be returning to my med school alma mater as a faculty member, accepting a position as attending cardiologist at UCLA @UCLAHealth Grateful for my mentors, especially Drs. Matthew Budoff @BudoffMd, Quang Bui, Priya Pillutla, and Sam Daneshvar
We have the tools & know-how to bend this curve ⤵️. ✅ and manage #BloodPressure ✅ and manage blood glucose 🚭 discourage #smoking 🚶♀️ encourage & empower active living Begin preventive screenings and treatments early in life. @AmJPrevMed @amjhypertension @AMJPublicHealth
US heart failure deaths in 2021 reached levels not seen since 1999 healio.com/news/cardiolog… @JAMACardio @FudimMarat @ASayedMD @JavedButler1
A sad result presaged by Steve Sidney in 2017 & 2018 @NatForumHDSP Signature Reports (bit.ly/49THMHA). Fortunately, we know how to get back on track. Prevention must begin early in life. @cooney_liz @dmljmd @DrMarthaGulati @AnnMarieNavar @JamalRanaMD @kcferdmd…
Decline in heart failure deaths has been undone, led by people under 45 statnews.com/2024/04/24/hea… via @statnews @JAMACardio @NMHheartdoc @FudimMarat @JavedButler1 @ASayedMD
“Recent data suggest plateaus or reversals after long-standing declines in cardiovascular mortality, particularly for HF-related mortality” @JAMACardio #Cardiotwitter Read more👇 healio.com/news/cardiolog…
really compelling reminder of how much work is left to do
🚨Stunning!🚨 REVERSAL in the decline of heart failure ☠️ in the US 1999-2021 1999-2005 ⬇️ ☠️ 2005-2012 ⬇️ ☠️ 2012-2019 ⬆️ ☠️ 2019-2021 ⬆️⬆️☠️ Age-adjusted HF related ☠️ rates higher in 2021 vs 1999! WT😱🆘 jamanetwork.com/journals/jamac… @JAMACardio @FudimMarat