Gokhan Cucun @gkhnccn
Neurobiologist @KITKarlsruhe https://t.co/0rEp4HIaZ8 Karlsruhe, Baden-Württemberg Joined May 2013-
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Our latest work is out today in @ScienceMagazine: a self-organizing system that models organizer-driven patterning and commissural axon guidance in human neural development. This was achieved with human midline #assembloids by combining floor plate and spinal cord #organoids…
We have developed DELIVR, a user-friendly deep-learning pipeline for automatically detecting and analyzing cells from whole-brain images to map neuronal activity via cFOS. DELIVR uses virtual reality to substantially accelerate the generation of training data and is accessible to…
📣 Symposium 2050 at the University of Zurich Join us for this event exploring emerging directions in life sciences, presented by a diverse group of leading experts. Free and open to all! More info/register: ema.uzh.ch/RTTHF
Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress: nature.com/articles/s4159…
Today in @Nature, we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas. We built an interactive browser to explore the spatial data: walshlab.org/research/corte… Paper link below👇
We’re living through pretty unusual times, but we’re excited to share good news! Our CRISPRa-programmed #embryo model paper is out! Thanks to our amazing group @glodewijk_sci @sayakakozuki and collaborators. I hope the community finds this model useful for new discoveries #CRISPR
We’re living through pretty unusual times, but we’re excited to share good news! Our CRISPRa-programmed #embryo model paper is out! Thanks to our amazing group @glodewijk_sci @sayakakozuki and collaborators. I hope the community finds this model useful for new discoveries #CRISPR https://t.co/s6hDYmvhXm
A great school to learn the finest all optical experiments from the @EmilianiLab and world experts on in vivo single cell manipulation at ms resolution, voltage population imaging and more : sign up now to secure your spot!
A great school to learn the finest all optical experiments from the @EmilianiLab and world experts on in vivo single cell manipulation at ms resolution, voltage population imaging and more : sign up now to secure your spot!
I really enjoyed writing this Perspective for the special issue on Neuroscience. It's an exciting time to study the human brain! Unraveling mechanisms of human brain evolution: Cell cell.com/cell/fulltext/…
Our newest work is online now in Neuron @NeuroCellPress showing the generation of diencephaluc #organoids, assembly to form cortico-thalamic #assembloids and their application to discover defects following loss of function and gain of function mutations in CACNA1G, which are…
Cost of having DNA methylation: DNA replication by DNA polymerase epsilon is a source of C to T mutations in CpGs, especially methylated ones. This expands our understanding of one of the most widespread endogenous mutational mechanisms. nature.com/articles/s4158…
We're excited to share our new study on the role of the ABCA7 gene in brain resilience against #Alzheimer’s. Published in @CellGenomics, we found that ABCA7 is crucial for maintaining synaptic health by regulating #neuropeptide Y (NPY), a key molecule for brain communication and…
Save the date 7-8/10/2024 : GDRImabio will co-organize with @Fr_BioImaging a workshop on "High Resolution 3D Microscopy in Biology: Development & Applications", happy to welcome @JungmannLab @Sciezgin Sophie Brasselet @Gaelle_Recher and Virgile Viasnoff, call for abstract soon !
Update - Motor school following Brain prize @Cajal_Training @bdxneuroschool Apply by **July 22** for in vivo mini projects on neuropixels, behavior in humans, all optical experiments for connectivity mapping in brainstem, test how many command neurons elicit motor actions & more!
Update - Motor school following Brain prize @Cajal_Training @bdxneuroschool Apply by **July 22** for in vivo mini projects on neuropixels, behavior in humans, all optical experiments for connectivity mapping in brainstem, test how many command neurons elicit motor actions & more!
Online now: Axonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions dlvr.it/T7ZBJM
Very excited to share that our DELiVR method is now open access published @naturemethods. We created a simple, brain-wide cell analysis deep learning tool, no coding needed! Fiji Plugin makes it accessible to all. nature.com/articles/s4159… by @Dorie00 @Rami96614090 @moritz_negwer
Really excited to announce our international #WNT meeting 2024 in Heidelberg (Sept. 25-27). A great opportunity to meet amazing colleagues, discuss outstanding science, and think about the future of the field. Organised by @sfb1324 Please register here: sfb1324.de/wnt2024/
The Plasticity Team is making it happen! For those who strive to transcend disciplinary boundaries, we welcome you to our interdisciplinary symposium on #Plasticity, powered by the @CentreUnusual. More on #identity, #time and #mind translationalneuroscience.nl/news/the-shape…
Doing research abroad comes with its own set of social, emotional, and bureaucratic challenges. In our latest ecrLife post, @Izzie_Hb, @arorankita, and @RuchikaBajaj9 talk about the problems faced by our international colleagues and how to help them thrive tinyurl.com/mtpy36my
Today we are sharing our most complex #assembloid to date: a 4-part model of the human ascending neural somatosensory pathway generated by functionally integrating stem cell-derived cerebral cortical, thalamic, spinal and sensory #organoids. Check out the @biorxivpreprint and…
Non-neuronal brain cells modulate behaviour go.nature.com/42U1WPN

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