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Harsh @harsh3b

structural biologist, crystallography, cryoEM, simulations Joined April 2020
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Harsh retweeted
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Suzie Pun @SuziePun

3 years ago

This paper in @J_A_C_S reports a CD71 aptamer from our "failed SELEX" that found great use in T cell manufacturing.😍because it reflects the tenacity of a devoted team of scientists. @adesgeorges @UWBioE pubs.acs.org/doi/10.1021/ja…

Harsh retweeted
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JCIM & JCTC Journals @JCIM_JCTC

4 years ago

Small #Glycols Discover Cryptic Pockets on #Proteins for Fragment-Based Approaches pubs.acs.org/doi/10.1021/ac… #current_issue #Computational_Biochemistry

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Harsh @harsh3b

5 years ago

Thank you @PracticalFrag for an elegant and comprehensive summary of our work. @JCIM_ACS @iiscbangalore #SmallGlycols #CrypticPockets #ProteinTargets #DrugDesign

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Practical_Fragments @PracticalFrag

5 years ago

Thank you @PracticalFrag for an elegant and comprehensive summary of our work. @JCIM_ACS @iiscbangalore #SmallGlycols #CrypticPockets #ProteinTargets #DrugDesign

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Harsh @harsh3b

5 years ago

Always a fan of crystals and information content therein. Excited to share my corresponding author paper published in @JCIM_ACS. #SmallGlycols #EthyleneGlycol #PropyleneGlycol #CrypticPockets #HotSpotMapping #ProteinTargets #DrugDesign pubs.acs.org/doi/10.1021/ac…

Harsh retweeted
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Frank von Delft @FrankvonDelft

5 years ago

Second call: help us help you! Later this decade, we want to seriously crank up XChem #xchemfrags with a new beamline K04 in Diamond-II - that's 15x more fragment screening, so far more and far faster chemical biology and drug discovery for more experiments. To support:

Harsh retweeted
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Debayan (Deb) Dey @DebDey_EmoryU

5 years ago

@abhisekhsingha1 @NatureComms @joachimfrank @desGeorgesLab Fantastic work @abhisekhsingha1 @adesgeorges @joachimfrank ..I was following it in bioRxiv for sometime..this opens a lot of possibilities in understanding functional pathways and allosteric transitions using cryo EM and computation.

Harsh retweeted
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desGeorgesLab @desGeorgesLab

5 years ago

Obtaining energy landscapes from Cryo-EM data, here it is, applied to the giant Ryanodine receptor! A great collaboration between @GroupOurmazd, @desGeorgesLab, @joachimfrank, @abhisekhsingha1 with Ali Dashti and Ghoncheh Mashayekhi leading our crowd! doi.org/10.1038/s41467…

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