I had the privilege to present the new episode of "case of the month" series. Many thanks to @dokemal for his efforts in bringing out 50 brilliant case of Hacettepe Pathology. A huge intraabdominal tumor! #gynpath youtu.be/wJumA-bs6n8?si… @YouTube aracılığıyla

We are looking for gyn pathology-interested residents, fellows and early career pathologists to present at ISGyP LiVE journal club! Mentored online presentation, networking, CV building and education. Message me if interested. #gynpath @ISGynP

New in #HumPathol: Uterine adenosarcoma: clinical significance of histological classification and SNP array analysis. sciencedirect.com/science/articl… #pathology #PathTwitter #PathX #gynpath

Announcing a free @ISGynP sponsored live virtual webinar on 05/02 by Dr. Dong on "Molecular Testing in Gynecologic Pathology". Register now at isgyp.ca #gynpath #pathtwitter #pathology

35 yo woman with vulvar mass. 15cm & infiltrative on CT. Your diagnosis? WSI digital slide: kikoxp.com/posts/4598. Answer & video: kikoxp.com/posts/9330. #pathology #BSTpath #pathologists #pathTwitter #gynpath #dermpath

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The BAGP is planning a full day hybrid ‘Meet the Experts’ Meeting, aimed primarily at early career pathologists and trainees. International gynae path experts will be sharing interesting cases. Link to book: thebagp.org/event/meet-the……… #BAGP2024 #GynPath #PathTwitter #Gynaepath

Bicornuate uterus 🔸Due to impairment in the fusion of Müllerian ducts. 🔸Isolated or associated w/ uterine & genital malformations (v.g. renal agenesis). 🔸Longitudinal vaginal septum is observed in 25% of cases. 🔸Associated w/ adverse reproductive outcomes. #PediPath #GynPath

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Later #career pearls from the best in the #pathology business: 💡 Study many cases. Form theories based on data, not diagrams. 💡 Ego = 1 / knowledge. Dr. Elvio Silva #GynPath conference Houston Society of Clinical Pathology 4/27/24

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Jaclyn Rudzinski, MD @JLRudzinskiMD

3 days ago

Later #career pearls from the best in the #pathology business: 💡 Study many cases. Form theories based on data, not diagrams. 💡 Ego = 1 / knowledge. Dr. Elvio Silva #GynPath conference Houston Society of Clinical Pathology 4/27/24 https://t.co/17utog2ZMc

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Myxoid leiomyosarcoma. Deceptively bland at high-power. A low-power diagnosis, and tumor was invading the vena cava in discussing with the surgeon. Mesenchymal Tumors of Uterus Dr. Esther Oliva #GynPath conference Houston Society of Clinical Pathology 4/27/24

The gross is the diagnosis. Based on squeezing the tissue, difference between edematous and myxoid-types of leiomyomas is contents. If water 💧 comes out, edematous; or if gelatinous material, then myxoid. Mesenchymal Tumors of Uterus Dr. Esther Oliva #GynPath HSCP 4/27/24

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Epithelioid Leiomyosarcoma. Has a distinct molecular signature (FISH). There is a long DDx. One to call out, PEComa because it has MTOR therapy available. Mesenchymal Tumors of Uterus Dr. Esther Oliva #GynPath conference Houston Society of Clinical Pathology 4/27/24

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Ovary, adult granulosa cell tumor is always in the differential diagnosis for fibroma, thecoma. Inhibin IHC and Reticulin stain, peri-cellular pattern. Ovary talk. Oluwole Fadare, MD #GynPath conference Houston Society of Clinical Pathology 4/27/24

A comparison of IHC for undifferentiated and FIGO grade 3 endometrioid Ca. Dr. Elvio Silva Houston Society of Clinical Pathology 4/27/24 #GynPath conference

Jaclyn Rudzinski, MD @JLRudzinskiMD

3 days ago

A comparison of IHC for undifferentiated and FIGO grade 3 endometrioid Ca. Dr. Elvio Silva Houston Society of Clinical Pathology 4/27/24 #GynPath conference https://t.co/KEwaOGPB7X

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Leiomyoma with bizarre nuclei. HL-RCC syndrome #gupath The bigger the nucleoli, the more likely to have a germline mutation. IHC, FH (less reliable) and 2SC. Mesenchymal Tumors of Uterus Dr. Esther Oliva #GynPath conference Houston Society of Clinical Pathology 4/27/24

Benign uterine smooth muscle tumors: Apoplectic leiomyoma. Up to 9 or 10 mitoses, OK to call it benign mitotically active. Symplastic aka bizarre nuclei. Mesenchymal Tumors of Uterus Dr. Esther Oliva #GynPath conference Houston Society of Clinical Pathology 4/27/24

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Features of POLE exonuclease domain mutation: Early stage, High-grade endometrioid type, Tumor infiltrating lymphocytes, *Good* clinical outcomes / favorable prognosis. Endometrial Ca., Dr. Robert Soslow #GynPath conference Hou Soc of Clinical Pathology 4/27/24

Example of Dx with Morphology that is bland, Molecular signature aggressive. Meso-nephric like carcinoma: Histologically bland. ER negative. Copy Number Low molecular group. Endometrial Ca., Dr. Robert Soslow #GynPath conference Houston Society of Clinical Pathology 4/27/24

Cytoplasmic p53 is an aberrant pattern. Along with Diffuse/Strong and Null. Endometrial Ca., Dr. Robert Soslow #GynPath conference Houston Society of Clinical Pathology 4/27/24

Steroid cell tumor, evaluate for features of malignancy. Ddx: Leydig cell tumor, even when benign can see perineural invasion by tumor cells in the hilum. Ovary talk. Dr. Oluwole Fadare #GynPath conference Houston Society of Clinical Pathology 4/27/24

Ovary, Luteinized Thecoma can be associated with *sclerosing peritonitis.* Latter is a potentially fatal dx. IHC talk, Dr. Michael Deavers #GynPath conference Houston Society of Clinical Pathology 4/27/24