Wang et al. developed wellDR-seq for co-profiling single-cell whole genomes and transcriptomes at scale and analyzed 33,646 single cells from 12 estrogen-receptor (ER)-positive breast cancers to understand disease progression ➡️ cell.com/cell/abstract/… #SingleCell #SpatialOmics

🔬 CZI Workshop at scverse 2025 🔬 Multimodal And Spatial Single Cell Data: From Data APIs to AI-driven Biological Discovery 🧵 @ChanZuckerberg #scverse2025 #SingleCell #SpatialOmics #CELLxGENE #VirtualCells #AIBiology

Rohan Misra … Deyou Zheng created an online server for the community to upload their single cell data and interactively make UMAPs with different hyper-parameters to witness how the distribution of cell clusters changes. ➡️ biorxiv.org/content/10.110… #SingleCell #SpatialOmics

Henry et al. generated a comprehensive map of cell type-specific causal gene-trait relationships across 28 peripheral immune cell types and 100 complex traits by integrating population-scale sc-eQTL data with GWAS ➡ medrxiv.org/content/10.110… #singlecell #spatialomics

SPEX: A modular end-to-end platform for high-plex tissue spatial omics analysis. #SpatialOmics #SingleCell #SpatialAnalysis @GigasSience academic.oup.com/gigascience/ar…

From nerve damage that blocks #Immunotherapy to mitochondria hand-offs, mechanical squeezing, & smarter spatial integration—this week’s weekly reads show cancer is a master of tricks 🧠🧬 #CancerResearch #SpatialOmics #CompBio open.substack.com/pub/behindtheb…

The Tabula Sapiens Consortium … Stephen Quake reported Tabula Sapiens 2.0, which includes data from nine new donors, doubles the number of cells in Tabula Sapiens, and adds four new tissues. ➡️ biorxiv.org/content/10.110… #singlecell #spatialomics #spatialbiology

Yu Zhao ... Xun Xu introduced Stereo-seq V2, which employs random primers to capture and sequence RNAs in situ on FFPE sections and provides single-cell resolution. ➡️ cell.com/cell/fulltext/… #singlecell #spatialomics #spatialbiology #spatialtranscriptomics

Xu-Fei Du... Jiu-Lin Du built a whole-nervous-system single-neuron morphology atlas of excitatory and inhibitory neurons in larval zebrafish at 6 days post-fertilization. ➡️ biorxiv.org/content/10.110… #singlecell #spatialomics #spatialbiology #spatialtranscriptomics

Momenzadeh et al. summarized the latest progress in single-cell proteomics technology and software solutions: ➡️ sciencedirect.com/science/articl… #singlecell #spatialomics #spatialbiology #spatialtranscriptomics #singlecellanalysis

Updating knowledge on 10X Genomics single cell analysis today Very lucky to win the grand prize of Apple Air Tag during lucky draw #RNAseq #10xgenomics #scrnaseq #spatialomics #spatialoncology #transcriptomics

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Massimo Andreatta … Santiago Carmona summarized transcriptional aberrations and computational approaches that may aid the identification of malignant cells. ➡️ nature.com/articles/s4200… #singlecell #spatialomics #spatialbiology #spatialtranscriptomics #singlecellanalysis

Weekly reads 18/8/25: - Tumor architecture + nuclear shape fuel CRC heterogeneity - Viral infections awaken dormant #cancer - Engineered bacteria launch an oncolytic virus - Axonal injury drives #glioblastoma #SingleCell #SpatialOmics #SystemsBiology open.substack.com/pub/behindtheb…

A multi-scale, multi-context, and interpretable mapping strategy to map cells across space, time, and disease. @KJWonKJ #spatialMapping #spatialOmics #BiotechNatureComms nature.com/articles/s4146…

Sarah Dobner ... Laura de Rooij presented the Human Aging Endothelial Cell Atlas (HAECA), a harmonized single-cell transcriptomic compendium of over 375,000 endothelial cells from 12 human tissues throughout adulthood. ➡️ biorxiv.org/content/10.110… #singlecell #spatialomics

Submission Details: Submit your work: biomedcentral.com/collections/sb Deadline: 10 September 2025 Learn more: bmcmethods.biomedcentral.com Don’t miss this opportunity to contribute to spatial biology! 🌍✨ #SpatialOmics #BMCMethods #SingleCell #SpatialTranscriptomics #MassSpectrometry

⚡After a vacation, we are ready to share news in the single cell and spatial world. Here, you can find a list of key discoveries published last month: ➡️ linkedin.com/feed/update/ur… #singlecell #spatialomics #spatialbiology #spatialtranscriptomics #singlecellanalysis

Planning a @10xGenomics #Xenium or other #SpatialOmics project, but aren't sure how to prep and store samples? 🧬🧠💻🧪 Check out #DukeMGC Xenium project guidelines on our website at dmpi.duke.edu/cores/molecula…

🚀See the whole picture! Introducing Stereo-seq LCD V1.3! Capture more insights with enhanced efficiency and large chip sizes (up to 13cm x 13cm). Perfect for 3D spatial atlases and high-throughput projects. Elevate your researches today! bit.ly/4fHD8Rs #SpatialOmics

Multiplexed spatial transcriptomics on biopsy specimens reveal cellular niches driving inflammation in IBD, guiding targeted biologic therapies .#SpatialOmics #IBD