#mitochondria - #Ionchannels : Mitochondrial calcium uniporter channel gatekeeping in cardiovascular disease. nature.com/articles/s4416…

This week is 25 years since my first paper was published as a postdoc at @UWMedicine with Bill Catterall. Writing this obituary brought back memories. RIP Bill. Thx @sgpweb for the feature. sgpweb.org/inmemoriam #ionchannels

The Springer publication 'Ion Channels as Targets in Drug Discovery' examines current success stories in ion channel targets and discusses major drug discovery programs in industry. hubs.la/Q02vRq4_0 #ionchannels #drugdiscovery

Steve Jenkinson is looking forward to hearing about the latest work of the HESI Cardiac Safety Committee at this workshop next week. Steve is attending the meeting virtually but you can contact Steve here: hubs.la/Q02vJj270 #drugdiscovery #ionchannels #cardiacsafety

Autocrine activation of P2X7 receptor #IonChannels mediates catecholamine secretion in chromaffin cells buff.ly/4dnjpF9

#Ionchannels might be key to treating Duchenne Muscular Dystrophy (DMD)! 🔎 New #research shows they could be biomarkers & drug targets. nyaspubs.onlinelibrary.wiley.com/doi/epdf/10.11… @NYASciences @RoyalVetCollege

A triple cysteine motif as major determinant of the modulation of neuronal KV7 #Ionchannels by the paracetamol metabolite N‐acetyl‐p‐benzo quinone imine - Ray - British Journal of Pharmacology @BrJPharmacol buff.ly/3y5QMMg

Mutation in pore-helix modulates interplay between filter gate and Ba²⁺ block in a Kcv channel pore. A new study from Noel Tewes, Oliver Rauh and colleagues @TUDarmstadt: hubs.la/Q02tNwm50 #Biophysics #MembraneTransport #MolecularPhysiology #ProteinStructure #IonChannels

Toxins!! Such an interesting reading From foes to ion channel targeting and drug discovery 🧪 With cutting-edge tech we are a step closer to new therapeutic opportunities. #DrugDiscovery #Toxins #ionchannels link.springer.com/chapter/10.100…

Cannabidiol potentiates hyperpolarization-activated cyclic nucleotide–gated (HCN4) channels, say Dana Page and Peter Ruben @SFU_Science: hubs.la/Q02tNHWm0 #MolecularPharmacology #CardiacMuscle #MolecularPhysiology #Biophysics #IonChannels

Targeting #ionchannels with ultra-large library screening for hit discovery buff.ly/44sQgUY

Temperature modulates PVN pre-sympathetic neurones via transient receptor potential #ionchannels buff.ly/4bhnskl

The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5 #ionchannels buff.ly/3QMzYkf

Are you striving for increased diversity and efficiencies in screening and target identification? Combine your libraries with the power of our specialist #ionchannels and high-throughput #screening and hit-finding expertise: hubs.ly/Q02tKVHY0 #cro #drugdiscovery

⏱️ Registration for the Cambridge Ion Channel Forum closes tomorrow, 30th April. Join us on 8th May to hear #drugdiscovery case studies and connect with fellow ion channel enthusiasts. 🔗 hubs.la/Q02tzy2Q0 #ionchannels #cicf24 #pharma #lifesciences

The QPatch® from @sophionbio is a fully automated #PatchClamp system designed to perform parallel gigaseal #ionchannel recordings of 16 or 48 cells. #drugdiscovery #PatchClamp #planarpatch #ephys #electrophysiology #QPatch #automatedpatchclamp #ionchannels

Interesting. @DrJonLippiat @IonChannelLeeds #viroporins #viral #ionchannels #SARSCoV2 #Covid

Just Here For The News @ktho641521

a week ago

Interesting. @DrJonLippiat @IonChannelLeeds #viroporins #viral #ionchannels #SARSCoV2 #Covid

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GWAS: Upregulated GIRK2 #IonChannels Counteracts Ethanol-Induced Changes in Excitability and Respiration in Human Neurons | Journal of Neuroscience buff.ly/4b5L778 £€$¥

Dynamic Gain Decomposition Reveals Functional Effects of Dendrites, #IonChannels, and Input Statistics in Population Coding buff.ly/3U9DcyN £$¥€

Very Important Thread by @ejustin46 on Thread Reader App threadreaderapp.com/thread/1705595… If you haven't been following @ejustin46 you should be. #SARS2Receipts #PandemicChangeAlert #VIROPORIN #IonChannels #MutationT9IintheEPROTEIN