NeuroScienceAdvance @hlpan61
Texas, USA Joined March 2018-
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Gαq signaling contributes to opioid-induced NMDA receptor hyperactivity at nociceptor central terminals by promoting mu-opioid receptor-mGluR5 cross-talk. pubmed.ncbi.nlm.nih.gov/40892896/
Gαq signaling contributes to opioid-induced NMDA receptor hyperactivity at nociceptor central terminals by promoting mu-opioid receptor-mGluR5 cross-talk. pubmed.ncbi.nlm.nih.gov/40892896/
A Science Signaling study shows that the stimulatory G protein, Gq, switches opioid actions from analgesia to hyperalgesia: science.org/doi/10.1126/sc…
How do opioid drugs induce opioid paradox? science.org/doi/10.1126/sc…
How do opioid drugs induce opioid paradox? science.org/doi/10.1126/sc…
A new study published in #Science #Signaling demonstrating that #Gαq in #pain-sensing neurons shifts #opioid #analgesia to #NMDA receptor–driven tolerance and hyperalgesia. @scisignal
A new #Circulation #Research publication has identified reduced #brain #calcineurin activity as the potential cause of #idiopathic #hypertension. mdanderson.org/newsroom/resea…
A new #Circulation #Research study shows that essential (primary) #hypertension, or hypertension with no identifiable cause, results from diminished #calcineurin activity in the #brain. ahajournals.org/doi/10.1161/CI…
A comprehensive review of the #alpha2delta-1 protein and #gabapentinoid drug actions in #chronic neuropathic #pain. pubmed.ncbi.nlm.nih.gov/40191897/
Former President Jimmy Carter has died at age 100. What a life. What a legacy. Thank you, Mr. President.
A new #JBC publication shows how nerve injury causes upregulation of alpha2delta1, the target of #gabapentin and #pregabalin, in sensory neurons. jbc.org/article/S0021-…
#DNA #Demethylation in the #Hypothalamus Promotes #Transcription of #angiotensin Agtr1a and Slc12a2 and #Hypertension Development. jbc.org/article/S0021-…
A new #JBC study shows the #epigenetic control of pro-hypertensive #genes in the #brain during age-dependent development of #hypertension. pubmed.ncbi.nlm.nih.gov/38160798/
lin deng @dlljj
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