#meansystemicpressure #haemodynamic #hemodynamic #Guyton case example. Severe pancreatitis, large volume fluid resuscitation, not sedated or ventilated. Cardiac output monitor shows a high CO and low SVR

Venous return (& therefore CO), assuming an efficient heart, is driven, and controlled by, the pressure gradient from the venules to the right heart. This venular pressure is analogous to mean systemic pressure (Pms) & is determined by the volume & compliance of the venules.

A common haemodynamic scenario we see in critical care is a hyperdynamic circulation with a high CO and low SVR. A question that then arises is ‘if the SVR is low, and if this signifies low vascular tone, how can Pms be high to drive a high CO?’