Patient presents with new onset seizures. MRI shows a frontal lobe mass. Diagnosis? What findings would you expect on molecular studies? Answer and pearls in the comments! #PathTwitter #meded #neuopath
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@ihartpathology Oligodendroglioma- Fried egg appearance
@ihartpathology Oligodendroglioma. “Fried egg appearance.
@ihartpathology Classic images
@ihartpathology Looks like Oligodendroglioma. It should have IDH mutation and 1p/19q-codeletion (by definition). TERT promoter and/or CIC mutation can also be present.
@ihartpathology Oligodendroglioma IDH mutant 1p19q codeleted