Mahé Isabelle @isabellemahe1
Cardiovascular Disease and Internal Medicine in @univ_paris_cite @APHP @INNOVTE1 Colombes, France Joined October 2021-
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#AQUATICtrial 🇫🇷: In chronic coronary syndrome pts at high 🫀atherothrombotic risk on long-term oral anticoagulation (OAC), adding ASA ↑ CV events (HR 1.53), death (HR 1.72) & major bleeding (HR 3.35) without benefit. OAC alone safer. Published in @NEJM nejm.org/doi/full/10.10…
🚨 *St Francis Heart Center, NY CardioOncology Journal Club* @isabellemahe1 (@univ_paris_cite) joined us to discuss API-CAT trial: whether among active cancer patients with VTE, tx with a ⬇️ dose Apixaban prevents recurrent VTE, ⬇️ bleeding🩸: opci.live/opci-lives/ext…
Extended reduced-dose DOAC: APICAT / RENOVE - Prof. Isabelle Mahé / Prof. Francis Couturaud youtu.be/RXttWKQ-sM4?si… @isabellemahe1 and @FCouturaud discuss the use of reduced-dose NOAC treatment for extended treatment of VT, based upon their APICAT and RENOVE trials.
Isabelle Mahé (@isabellemahe1) Shares an Insight from APICAT Study: Use of Apixaban in Cancer Associated Thrombosis @NEJM @MarcCarrier1 @SilvyLaporte @isth hemostasistoday.com/science/isabel… #APICATStudy #Apixaban #MedEd #MedX #CancerAssociatedThrombosis #Health #Hematology…
How do you manage oral anticoagulants in patients undergoing an invasive dental procedure? Our prospective national study suggests a short DOAC discontinuation before the invasive dental procedure can minimize bleeding! @RPTHjournal @isth @ESC_Journals doi.org/10.1016/j.rpth…
How do you manage oral anticoagulants in patients undergoing an invasive dental procedure? Our prospective national study suggests a short DOAC discontinuation before the invasive dental procedure can minimize bleeding! @RPTHjournal doi.org/10.1016/j.rpth…
Best. Present. Ever.
Study API-CAT: Low-dose apixaban proved noninferior to full-dose for extended #VTE prevention in active cancer—with significantly less bleeding. Practice-changing. bit.ly/3E4UxFk #ACC25 #Oncology @isabellemahe1 @DSadlerMD @SimonNoble @NEJM
💊 Discontinuation of #VKA in patients with life-limiting disease ⬇️ 📌 Among 18,000+ 🇳🇱 VKA users, >80% continued anticoagulant until 1 month before death 📌 Similar rates of bleeding and thromboembolism during and after VKA discontinuation 🆓👉 thieme-connect.de/products/ejour…
Study API-CAT: Extended low-dose #Apixaban (2.5 mg BID) is noninferior to full-dose for #VTE prevention in cancer—with less bleeding. A potential practice-changer. bit.ly/4jjl4h5 @isabellemahe1 #ACC25 #VTE #Oncology
In the API-CAT trial involving patients with active cancer and venous thromboembolism, extended anticoagulation with reduced-dose apixaban was noninferior to full-dose apixaban for preventing recurrent thromboembolic events. Full trial results and Research Summary:…
Original Article: Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism (API-CAT) nej.md/41YkRZK Editorial: Cancer-Associated Venous Thromboembolism — Beyond 6 Months nej.md/4iB6wcA #Cardiology
NEJM | API-CAT 💊💊 Apixaban 2,5 mg x2/j ≈ 5 mg x2/j après 6 mois chez patients #cancer & #MTEV 🟰Incidence récidive : 2,1% vs 2,6% N. 🩸Moins de saignement: 12,1 vs 15,6 S ➡️ Non infériorité + meilleur profil de tolérance nejm.org/doi/full/10.10… @isabellemahe1 @OncoAlert
New Paper Alert: Reduced-Dose Apixaban Found Effective for Extended Treatment of Cancer-Associated VTE @isabellemahe1 @MarcCarrier1 @MayeurDidier @juanjolopezn @HRobertEbadi oncodaily.com/oncolibrary/re… #AnticoagulantTherapy #Apixaban #CancerCare #MedX #MedEd #OncoDaily #Oncology…
Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism Extended anticoagulation with reduced-dose apixaban was noninferior to full-dose apixaban for the prevention of recurrent venous thromboembolism in patients with active cancer nejm.org/doi/full/10.10…
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