Sethu Vinai @karthicksethu
Engineering | Startups @zerodownhq. @zenefits, @deshawgroup linkedin.com/in/karthickset… San Francisco Joined March 2009-
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When leading an eng project you have four dimensions in your control: resources (people), timeline, quality, scope. People cost money and take time to ramp up. Timeline slips and hurts the business. Low quality hurts velocity and puts customers at risk. Usually the only real…
What a time to be working on healthcare AI
Joy is having snake gourd koottu using fresh gourd a neighbor dropped off and a recipe my Mom wrote for me eons ago...
Chillax! #NoteToSelf
we are opening our first office in india later this year! and i'm looking forward to visiting next month. ai adoption in india has been amazing to watch--chatgpt users grew 4x in the past year--and we are excited to invest much more in india!
A not so well known fact abt Sundar Pichai is that he was promoted into the CEO role not because he was the smartest person in the room but because without him it was getting very hard to get a group of very smart people to agree on anything. High IQ + low ego is a killer combo.
A not so well known fact abt Sundar Pichai is that he was promoted into the CEO role not because he was the smartest person in the room but because without him it was getting very hard to get a group of very smart people to agree on anything. High IQ + low ego is a killer combo.
Subtle but very true why companies remain mid.
A truism of CS is that you need to understand at least one level of abstraction below where you operate. - OS devs -> hardware - systems devs-> OS - app devs-> systems Vibe coding is no exception.
Writing 10x prompts will be regarded with similar awe and reverence as we have today for cracked 10x engineers
People don’t care what you built. They care that you finally named the problem they’ve been dealing with all along. Startups don’t fail because the solution is weak. They fail because no one feels the problem enough to act. You can’t create demand without pain. And if your…
Do yourself a favour by bookmarking this.
https://t.co/wudpLsmjTO
I'm starting something soon. Join me in making state-of-the-art AI models for the world from 🇮🇳India.
Just like that, over the weekend, the value of so-called GPT wrappers and models/GPUs are swapping spots. #DeepSeekR1 #NVDA
Contrary to the common narrative, I find that AI helps stronger, more experienced programmers a lot more then it does less experienced programmers. They have the context for what to ask about, how to evaluate the responses, and the tools to handle large code disruptions.
100% - the most overlooked benefit of code gen tools: they make you want to build again. Haven't felt this energized about coding in years 🚀
Identifying and building out sustainable moats in AI is one of the most important and exciting topics if you're in software right now. Given the fact that there are multiple at-scale frontier AI model providers with effectively infinite budgets, training data appears to be…
🇮🇳 Gukesh D 🥹 Ladies and gentlemen, the 18th WORLD CHAMPION! #DingGukesh
All code is temporary. Trying to make it perfect so it doesn't have to change is futile, and hacking it out as if you'll never have to come back to it is a recipe for disaster.
Anyone who says Elon doesn't deserve any credit for spacex, the engineers who did all the work do, has never tried to get a bunch of engineers to make anything

Varunkumar Nagarajan @varunkumar
2K Followers 952 Following Indian. Responsible son. Software Engineer. Coder. Blogger. Technology enthusiast. Web developer. Glass Xplorer. Gardener. Cricket lover. RS Dravid Fan. Foodie.
Kuberan Marimuthu (Ku... @ikuberan
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Srikanth.CashlessCons... @logic
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Everstage @everstageinc
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Barry / TxLabz.com @BarryTxlabz
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Sandeep Khanna @sandeepkhannavp
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Sisynde @sisynde28745
72 Followers 7K Following The bravest act is still to think of yourself. speak loudly.
SabrinaHuggins @t5a09i2wdLqm4
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TheresaLongman @TKo9fp7G8Htq1
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PrudenceBurke @n7zwk6lN395arP
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Harland @kunimitsuw59219
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Kamesh Chandrasekar @kam__esh
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MarciaDupont @pt7v7dwcoYfu1Gx
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Sidhaarth A @sidhaarth_a
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MurielDavid @lYIT8DFHEjyQd4
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Eric @lepomjames
384 Followers 373 Following Having fun. startups and investing. recovering consultant. teenage dad
Seseat @Seseat143383
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Viatrix @Viatrix255263
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อาฉี หา�... @HayXachi
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Evangeline_ @Evangel44229351
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Parag Paul @rahiakil
1K Followers 7K Following Founder #BYOD & RigAI Founder, CTO of KnockADoc, Post Doc Res. 20 years in tech, Microsoft, Synopsys. Books and Companies. Crypto all the way.
Sasysmay @sasysmay59750
126 Followers 3K Following I'm new to Twitter accounts so I tried the messaging feature and it's great to meet you.
Thesmeb @Thesmeb179812
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Paul Graham @paulg
2.1M Followers 774 Following
Varunkumar Nagarajan @varunkumar
2K Followers 952 Following Indian. Responsible son. Software Engineer. Coder. Blogger. Technology enthusiast. Web developer. Glass Xplorer. Gardener. Cricket lover. RS Dravid Fan. Foodie.
Sriram Krishnan @sriramk
302K Followers 1K Following White House Senior Policy Advisor for AI. pro wrestling fan. official: @skrishnan47
Garry Tan @garrytan
603K Followers 5K Following President & CEO @ycombinator —Founder @Initialized—designer/engineer who helps founders—San Francisco Dem accelerating the boom loop—e/acc—technology brother
Aaron Levie @levie
2.6M Followers 717 Following ceo @box - unleash the power of your content with AI
Kuberan Marimuthu (Ku... @ikuberan
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martin_casado @martin_casado
68K Followers 3K Following GP @ a16z ... questionable heuristics in a grossly underdetermined world
Mike Maples, Jr @m2jr
106K Followers 8K Following I invest way too early in outlier startups. Twitter (as Odeo), Twitch (Justintv), Okta (Saasure), Applied Intuition. Partner @floodgatefund. Bestselling author.
Andrew Gazdecki @agazdecki
269K Followers 7K Following Founder and CEO of @acquiredotcom. https://t.co/wRMIssDmhl has helped 100s of startups get acquired and facilitated $500m+ in closed deals.
Semil @semil
154K Followers 848 Following Investor via @HaystackVC focused on seed-stage investments // Venture Partner w/ @LightspeedVP
Everstage @everstageinc
2K Followers 1K Following Built by RevOps for RevOps. The sales compensation vendor of choice for industry leaders like Notion, Postman, Diligent, Chargebee, Wiley & Paychex etc.,
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21K Followers 1K Following Co-founder/CEO @stilt_inc (acq by JGW). YC W16. Immigrant. Founder helper. Buying VC-backed companies. Building AI products. Angel Investor.
Local Tea Party @localteaparty
15K Followers 754 Following The pen is mightier than the sword and all ok, but don't try to fight with a pen. Otherwise there will be ink all over you.
Noah Kagan @noahkagan
169K Followers 118 Following Chief Sumo at @appsumo. #30 at Facebook. Helping entrepreneurs 👉 https://t.co/nDWitfclod
Jessie Frazelle @jessfraz
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Vivek Suriyamoorthy @vivek__s
255 Followers 410 Following CTO @everstageinc 👨💻 , Building No-code SaaS and Reimagining SaaS with LLM agents 🤖
TVK Vijay @TVKVijayHQ
540K Followers 1 Following தலைவர், தமிழக வெற்றிக் கழகம் - த.வெ.க | President, Tamilaga Vettri Kazhagam - TVK
Yuchen Jin @Yuchenj_UW
54K Followers 536 Following Co-founder & CTO @hyperbolic_labs 🧑🍳 fun AI systems. Previously: OctoAI (acquired by @nvidia) building @ApacheTVM, PhD @uwcse 🤖
Shengjia Zhao @shengjia_zhao
52K Followers 230 Following Chief Scientist @ Meta MSL. Formerly MTS @ OpenAI, PhD @ Stanford. I train models. All opinions my own.
jordwalke @jordwalke
64K Followers 729 Following Created @reactjs and @ReasonML. Formerly @facebook. Product at @replit
Orrick @Orrick
9K Followers 504 Following A global law firm focused on serving the tech & innovation, energy & infrastructure, finance and life sciences & healthtech sectors. https://t.co/ANNte3jUyz
DeepSeek @deepseek_ai
973K Followers 0 Following Unravel the mystery of AGI with curiosity. Answer the essential question with long-termism.
Peter Zakin @pzakin
5K Followers 5K Following Partner @upfrontvc. Sold Hyper Travel to @tradeshift. ex @venmo, @usemacro, YC S2010. Latest post: https://t.co/pBTXxEURWz
Pierre Poilievre @PierrePoilievre
1.5M Followers 1K Following @CPC_HQ leader, running to be Prime Minister of Canada - Chef du @PCC_HQ, candidat au poste de premier ministre du Canada
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19K Followers 756 Following Founder & CEO @BrexHQ, helping 30k+ companies (from startups to the largest companies on the planet) to spend smarter and move faster.
steijnpelle @steijnpelle
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Trisha Gee @trisha_gee
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365K Followers 8 Following Vercel provides the developer tools and cloud infrastructure to build, scale, and secure a faster, more personalized web. Creators of @nextjs, @v0, and @aisdk.
Linear @linear
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Simon Willison @simonw
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kache @yacineMTB
196K Followers 6K Following canadian startup founder. prev eng @ x, stripe. yacine_kv on insta i make my memes with https://t.co/pWRBfY8kn2 - I write a subscriber only blog. Subscribe!
Kashyap Sriram @kashyap286
21K Followers 637 Following Indian expat living the good life in Dubai | 9+ years in capital markets | Gold Bug | Energy Bull | Macro Expert | Rode $SOL from $11 to $220 | MBA - IIT Madras
BURKOV @burkov
47K Followers 110 Following My new LM book: https://t.co/YXNQUy7O3t PhD in AI, author of 📖 The Hundred-Page Language Models Book and 📖 The Hundred-Page Machine Learning Book
Greptile @greptileai
3K Followers 10 Following We're building AI that catches bugs in pull requests. Join us :)
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Jan Leike @janleike
115K Followers 332 Following ML Researcher @AnthropicAI. Previously OpenAI & DeepMind. Optimizing for a post-AGI future where humanity flourishes. Opinions aren't my employer's.
Jaana Dogan ヤナ �... @rakyll
125K Followers 1K Following Principal Engineer at Google. Gemini + model serving at large. Simplicity and optimism. Personal opinions.
Dwarkesh Patel @dwarkesh_sp
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210K Followers 359 Following I build & teach AI stuff. Founder @TakeoffAI where we’re building an AI coding tutor. Come learn to code + build with AI at https://t.co/oJ8PNoAutE.
sarah guo @saranormous
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216K Followers 2K Following waiting for agi. i live to experiment. don't take me too seriously I am an idiot. trying to build distractions (content, AI tools, games) for a post AGI world.