Kuldeep Kumar @kkumar_iitkgp
Postdoc, CHUSJ. Investigating the impact of genomic variants on human brain, and link to psychiatric risk. IIT-Engineer-ISRO-Neuro-Genetics. Data --- Pattern. kkumar-iitkgp.github.io Montreal Joined July 2011-
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Kuldeep Kumar retweeted
We are looking for a PhD student interested in studying the brain-immune axis, to understand the interaction between the brain and the immune system in ageing and psychiatric disorders. Large-scale brain imaging biobanks and in house collected datasets will be analysed.
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Kuldeep Kumar retweeted
New Open dataset alert: 🧠 Introducing "Spacetop" – a massive multimodal fMRI dataset that bridges naturalistic and experimental neuroscience! N = 101 x 6 hours each = 606 functional iso-hours combining movies, pain, faces, theory-of-mind and other cognitive tasks! 🧵below
Kuldeep Kumar retweeted
Can we fuse adaptive and connectomic DBS? @neumann_wj & I say yes. Out in @NatRevNeurol: nature.com/articles/s4158… Thread here: shorturl.at/NtPMf
Kuldeep Kumar retweeted
🔥🔥Excited to announce that I am recruiting PhD students this fall. Our lab uses neuroimaging (MRI) and computational modeling to study the mechanisms of neurodevelopmental disorders, bridging genetic factor, brain circuitry, early life stress, and psychopathology. Please DM me
Nature | Single-cell transcriptomic and genomic changes in the ageing human brain Downregulation of short, highly expressed housekeeping genes with age, correlating with increased somatic mutation accumulation. Conversely, longer neuron-specific genes maintain their expression
Kuldeep Kumar retweeted
Most genetic reports label variants as ✅ “pathogenic” or ❌ “benign.” But what patients really want to know is: what are my chances of getting the disease? 🚨 In our new Science study, we used AI + 1.3M patient records to better answer that…
Kuldeep Kumar retweeted
Two flagship papers from the International Brain Laboratory, now out in @Nature: 🧠 Brain-wide map of neural activity during complex behaviour → doi.org/10.1038/s41586… 🧠 Brain-wide representations of prior information in mouse decision-making → doi.org/10.1038/s41586… +
Kuldeep Kumar retweeted
super cool, this used to take forever back when we were making AI simulation games like Republic.
super cool, this used to take forever back when we were making AI simulation games like Republic.
Kuldeep Kumar retweeted
Check out our new preprint on Streamline Density Normalization (SDNorm)! SDNorm can reduce bundle variability, improve reliability of along-tract microstructure, and provide metrics for automated bundle QC. 📎Paper: biorxiv.org/content/10.110… 📎Code: github.com/wendyfyx/SDNorm
Kuldeep Kumar retweeted
I was fortunate to work with my role model @foxmdphd . Thank you for the quality time you created for us, for the big encouragements, for the seemingly small yet powerful daily encouragements, for your consistency, for supporting us in challenging times, your genuine respect for…
Kuldeep Kumar retweeted
How can DBS to the memory circuit hurt cognition in some patients but improve it in others? New work led by @calvinwhow @Brain_Circuits suggests it’s due to patient age. Surprise - older patients do better across both PD and AD!
How can DBS to the memory circuit hurt cognition in some patients but improve it in others? New work led by @calvinwhow @Brain_Circuits suggests it’s due to patient age. Surprise - older patients do better across both PD and AD!
Kuldeep Kumar retweeted
🔥ATAXIA includes rare, inherited neurodegenerative diseases characterised by progressive deterioration in motor coordination + cognitive function. 🔥Ian Harding has been leading global efforts to pool data + expertise on these disorders + categorize these ataxias by age of…
Kuldeep Kumar retweeted
How A.I. documentation of clinic conversations has improved clinician experience, less burnout in >1,400 clinicians at 2 health systems @MassGenBrigham and @emoryhealthcare jamanetwork.com/journals/jaman…
Kuldeep Kumar retweeted
Epic work led by @ganjgahi is out in Nature Medicine... data-driven clustering of MS finds 3 distinct states, early/mild, active, advanced, w/ transition to the advanced state only occuring through the active state... replicated twice! doi.org/10.1038/s41591…
Kuldeep Kumar retweeted
🔥How does GENETIC RISK FOR DEPRESSION affect your brain? 🔥Extraordinary paper, out today [1], examines genetic risk for depression and brain MRI in 50,975 participants pooled from 11 studies within the ENIGMA Major Depressive Disorder Working Group 🔥People with higher genetic…
Kuldeep Kumar retweeted
Boom: Stop and go have new meaning in the basal ganglia. For decades, we thought of the basal ganglia in terms of two great circuits the GO (direct) and NO-GO (indirect) pathways. New work from Anne Graybiel and colleagues challenges this view. Fresh evidence shows that stop and…
Kuldeep Kumar retweeted
The lateral prefrontal cortex 🧠— which we think of as critical for goal driven behavior + is a target for psychiatric treatments— is fundamentally different in individuals relative to the group averages we’ve often studied. 👇see our preprint and thread, led by @zach_ladwig
The lateral prefrontal cortex 🧠— which we think of as critical for goal driven behavior + is a target for psychiatric treatments— is fundamentally different in individuals relative to the group averages we’ve often studied. 👇see our preprint and thread, led by @zach_ladwig
Kuldeep Kumar retweeted
Kuldeep Kumar retweeted
🔥BEAUTIFUL IN-DEPTH analysis of the BIPOLAR BRAIN [1], led by @Yanghee_Im in Chris Ching's lab, + bipolar disorder experts from 64 worldwide sites 🧠Surface-based toolkit -> Deep mapping of subcortical brain structure (N=3,373 people, 14 sites), w. interactive visualizations 🔥…
Kuldeep Kumar retweeted
🔥🔥Finally out!! Our new paper on the overlapping genetic basis of brain structures and psychiatric disorders has been published in @NatMentHealth. The list of shared genetic loci is also available online. Thank you so much, @Aaron_A_B and coauthors nature.com/articles/s4422…
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