Biophysicist based at EPFL applying the cutting edge in deep learning to protein design
Moved to BlueSky: https://t.co/0bwVvuHuFegithub.com/dclw29 Lausanne, SwitzerlandJoined July 2022
What does water do in the hidden depths of membrane proteins? A lot! Now published in @NatureChemistry (lnkd.in/ecb-ww5f) we rewire membrane protein allostery via water to improve GPCR efficiency - a protein so vital for cells 1/3 of drugs target them. Press release soon!
What a phenomenal achievement! Congratulations! @demishassabis, a CCF alumni! We wanted to extend our warmest heartfelt congratulations on your most recent accolade of the Nobel Prize in Chemistry. You continue to be such a huge inspiration to our students and staff!
What a phenomenal achievement! Congratulations! @demishassabis, a CCF alumni! We wanted to extend our warmest heartfelt congratulations on your most recent accolade of the Nobel Prize in Chemistry. You continue to be such a huge inspiration to our students and staff!
URGENT! Pls share. The last chance to register to vote in the General Election is 11.59pm tomorrow Tue 18 June. Potentially 8m aren't registered at their current address. Here's 4 key facts...
1) You can do it online here registertovote.service.gov.uk/country-of-res…
2) It's good for your finances.…
For the first time, researchers have sequenced RNA from an extinct animal species — the Tasmanian tiger.
Genetic sequences from a museum specimen offer fresh clues about the physiology of thylacines, which went extinct in the 1930s go.nature.com/48pG94W
EvoDiff combines evolutionary-scale data with diffusion models for controllable protein sequence generation.
In addition to generating plausible proteins, we can scaffold structural motifs in sequence space!
Preprint: biorxiv.org/cgi/content/sh…
Code: github.com/microsoft/evod…
In membrane protein structural biology, one draw back of implicit membrane modeling is stagnant geometry (e.g. flat membranes only).. until now!
Check out this preprint from Hope in the @MeilerLab on modeling alternative membrane geometries w/ Rosetta.
biorxiv.org/content/10.110…
Our thoughts on how conformational flexibility and switching properties are increasingly being considered (with lots of room for improvement) in deep learning methods for protein design!
frontiersin.org/articles/10.33…
792 Followers 185 FollowingReader at the University of Edinburgh, using molecular dynamics and machine learning to study protein structure and assembly.
213 Followers 542 FollowingExtreme enzymes for #proteomics and specialty applications. One-step/5-90 minute digests; Journal of Proteomics publication here (https://t.co/dCEJPtuMqA)
4K Followers 3K FollowingIUCrJ is a fully open-access peer-reviewed journal from the International Union of Crystallography (IUCr) reporting high-profile structural science.
253 Followers 549 FollowingDeep learning enthusiast🤖 Passionate about generating pixels👨🏻🎨 Lead of Computer Vision and AI at https://t.co/OkErpxQfmc & https://t.co/UGxl0quEFV apps👨🏻💻
284 Followers 701 FollowingBioengineeering PhD student at EPFL, CH. Master's Thesis at Harvard University, USA.
Drummer, biker, and FC Inter fan.
Born and raised in Mantua, Italy
16K Followers 4K FollowingScientist, Assistant Professor @MITBiology, #FirstGen, ProteinBERTologist, 🇺🇦
No Human is illegal.
Moving to: https://t.co/sow6IRD3jj
12K Followers 552 Following#ESRF, the European Synchrotron, is the world’s brightest light source. Its powerful X-rays are used to decipher the secrets of matter.
792 Followers 185 FollowingReader at the University of Edinburgh, using molecular dynamics and machine learning to study protein structure and assembly.
1K Followers 214 FollowingThe Center for Intelligent Systems at @epfl_en (CIS) brings together researchers working on different aspects of Intelligent Systems. Newsletter: https://t.co/g9V5JvDESm
3K Followers 899 FollowingCoordinating synthetic and engineering biology research and innovation across Bristol. Official account of the University of Bristol.
253 Followers 549 FollowingDeep learning enthusiast🤖 Passionate about generating pixels👨🏻🎨 Lead of Computer Vision and AI at https://t.co/OkErpxQfmc & https://t.co/UGxl0quEFV apps👨🏻💻
27K Followers 2K FollowingProfessor at UMD. AI security & privacy, algorithmic bias, foundations of ML.
Follow me for commentary on state-of-the-art AI.
284 Followers 701 FollowingBioengineeering PhD student at EPFL, CH. Master's Thesis at Harvard University, USA.
Drummer, biker, and FC Inter fan.
Born and raised in Mantua, Italy
1K Followers 198 FollowingAt Christ’s College Finchley we pursue academic excellence for all of our students; resolute in the belief that every child has great potential.
586 Followers 232 FollowingPostdoc @EPFL? You want to increase your network? develop your career path? find an ear, share some beer or create events? Join us!
561 Followers 45 FollowingThe AI4Science initiative promotes the use of machine learning in the scientific discovery process at EPFL.
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16K Followers 4K FollowingScientist, Assistant Professor @MITBiology, #FirstGen, ProteinBERTologist, 🇺🇦
No Human is illegal.
Moving to: https://t.co/sow6IRD3jj
986 Followers 340 Following"a universe of atoms, an atom in the universe.”
Official account for the Department of Physics, Durham University, UK.
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3K Followers 474 FollowingChemistry at Durham is a thriving centre of scientific activity for teaching and world-leading research in the chemical sciences.
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4K Followers 68 FollowingCECAM (Centre Européen de Calcul Atomique et Moléculaire) was founded in Paris in 1969 by Dr Carl Moser.
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232K Followers 953 FollowingThe IOP is the professional body and learned society for physics in the UK & Ireland. This account is not currently active.
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