Mathilde Foglierini-Perez @mathilde_fog
Computational immunologist @CHUVLausanne Joined August 2012-
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Mathilde Foglierini-Perez retweeted
scRepertoire now has a function to remove TCR/BCR VDJ genes from the variable features used for dimensional reduction. Friends don't let friends bias their clusters with indirect measures of clonal expansion. borch.dev/uploads/screpe…
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Mathilde Foglierini-Perez retweeted
Our most recent piece of work "The Patent and Literature Antibody Database (PLAbDab): an evolving reference set of functionally diverse, literature-annotated antibody sequences and structures" has just been released on bioRxiv (lnkd.in/esgbz-Gg)!!
Mathilde Foglierini-Perez retweeted
🚀 Major release of MiXCR v4.4: - 🤩 Built-in alleles database via vdj.online/library - 🧪 New rigorous quality control checks - 🤝 Simple way to build custom reference libraries - 🥹 Many other things Check out at: github.com/milaboratory/m…
Mathilde Foglierini-Perez retweeted
Clustering algorithms report clusters even when none exist. In single-cell RNA-Seq pipelines, novel cell types are often identified by clustering algorithms. Expanding on Kimes et al.'s work, we introduce significance analysis for single-cell RNA-Seq data: nature.com/articles/s4159…
🌟 Excited to share our new publication with @YannickDaMuller ! Intradermal skin test with mRNA vaccines as a surrogate marker of T ce... sciencedirect.com/science/articl…
Mathilde Foglierini-Perez retweeted
With sc-best-practices.org reaching more than 300 Github stars (github.com/theislab/singl…) it is time for a small resume. See thread below.
Mathilde Foglierini-Perez retweeted
We are excited to release Seurat v5- with new methods for multimodal, spatially resolved, and massively scalable single-cell analysis. satijalab.org/seurat
Mathilde Foglierini-Perez retweeted
🚀🥳 MiXCR 4.3: - 🤩 More powerful and precise filtering and thresholding for all UMI amplicon protocols - 🤝 Support of Seq-Well VDJ protocol (@shaleklab) - 🧪 Improved analysis of @NEBiolabs & @TakaraBioUSA XCR kits - 🥹Many minor improvements 🔗 github.com/milaboratory/m…
Mathilde Foglierini-Perez retweeted
Fantastic to see our team within the @bdsc_UNILCHUV collaborating with the @SDSCdatascience bringing even more #datascience expertise @CHUVLausanne
Fantastic to see our team within the @bdsc_UNILCHUV collaborating with the @SDSCdatascience bringing even more #datascience expertise @CHUVLausanne
Mathilde Foglierini-Perez retweeted
We are looking for a Senior Data Scientist for AI/ML in Healthcare and a Full-Stack Software Engineer. More info available here : recrutement.chuv.ch/vacancy/senior… recrutement.chuv.ch/vacancy/fullst… Check it out and retweet !
Mathilde Foglierini-Perez retweeted
🎄Christmas Launch 🚀!!! Now everyone can have FREE access to awesome tool to inspect your VDJ sequences online with MiXCR under the hood. Check it here: vdj.online 🎅
Mathilde Foglierini-Perez retweeted
My research on the immunoglobulin lambda locus in humans is published! Special thanks to @ctwatson29 @SmithLab_UofL and Oscar Rodriguez for their contributions. Turns out, there's some pretty cool stuff in the IGL locus! Who knew IG genes were so fun?! rdcu.be/c1ZmG
Mathilde Foglierini-Perez retweeted
@CancerResearch Postdoc Fellowship - consider joining our blooming Onco-Immuno-Informatics community in Lausanne! We're open for applications
@CancerResearch Postdoc Fellowship - consider joining our blooming Onco-Immuno-Informatics community in Lausanne! We're open for applications
Mathilde Foglierini-Perez retweeted
We are happy🎉to share our new study recently published in @EurJImmunol entitled “Clonal composition and persistence of antigen-specific circulating T follicular helper cells”. onlinelibrary.wiley.com/doi/10.1002/ej… A little thread 🧵1/10
Mathilde Foglierini-Perez retweeted
Are you, like us, wondering WHERE’S that CLONE? On behalf of the ‘Spatial VDJ’ team, here's full-length BCR and TCR mapping in human tissue using spatial transcriptomics (Visium). biorxiv.org/content/10.110… @thrane_kim @Qirongliiin @Jeff_Mold @FrisenJonas @joalunatkthse thread 1/n
Mathilde Foglierini-Perez retweeted
Bringing V(D)J analysis to the single-cell space is difficult. We continued to developed dandelion to help with this, finding some interesting new biology along the way in this new pre-print! @Cambridge_Uni @sangerinstitute @ClatworthyLab @teichlab biorxiv.org/content/10.110…
Mathilde Foglierini-Perez retweeted
Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced ant… pubmed.ncbi.nlm.nih.gov/36316475/ Congrats to the @hipcProject @ImmuneSpace team including Thomas Hagan, Rafick Sékaly, @skleinstein, and Bali Pulendran.
Mathilde Foglierini-Perez retweeted
Mathilde Foglierini-Perez retweeted
Presenting Slide-TCR-seq: our method for measuring the transcriptomes of cells & T cell receptor (TCR) sequences in situ! This collaboration w/ Bryan Iorgulescu, Shuqiang Li, Catherine Wu, and @insitubiology led to some cool findings... cell.com/immunity/fullt… 1/8
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