OSP Community @ospsuite

open-systems-pharmacology.org Joined October 2017

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OSP Community @ospsuite

4 years ago

Members from the OSP MT have conducted a 4-series workshop at FDA introducing the OSP Roadmap & Community and showcasing regulatory-level applications of the OSP Suite. The workshop material can be found here github.com/Open-Systems-P… #OSPS #pharmacology

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Pharmaceutics MDPI @MDPIpharma

5 years ago

#mdpipharmaceutics Denise Türk and co-authors are happy to share their Trimethoprim #PBPK model for DDI predictions! github.com/Open-Systems-P… #PKSim Read the article: mdpi.com/1999-4923/12/1…

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OSP Community @ospsuite

5 years ago

A Comprehensive Whole-Body Physiologically Based #pharmacokinetic Drug–Drug–Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals. A new publication about #antidiabetic drugs #pksim #science #pbpk #diabetes link.springer.com/article/10.100…

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OSP Community @ospsuite

5 years ago

A comprehensive online gallery of tutorials for #PKSim can be viewed here: youtube.com/c/clinicalphar… #PBPK #MoBi #OSPSuite #MIDD #pharmamodeling

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OSP Community @ospsuite

5 years ago

#ACoP11: Monica E. Susilo (Genentech) will present "A PBPK Platform Model for T Cell-Dependent Bispecific Antibodies using PKSim/Mobi" on Thu 12 Nov Session 5B (10 am EST) #PBPK #mAb #TDB #MoBi #MIDD #OSPSuite #systemspharmacology #opensource

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ASCPT Journal Family @ASCPTjournals

5 years ago

#PSPjournal #Pregnancy Virtual Issue: André Dallman and team (UKBB, @Bayer) share a Tutorial on using Open Systems #Pharmacology #PBPK software to model drug disposition in pregnant populations. @ospsuite #openscience bit.ly/3h3DyRX

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OSP Community @ospsuite

5 years ago

"Model qualification of the PK-Sim® pediatric module for pediatric exposure assessment of CYP450 metabolized compounds" A new publication on #Pediatrics #PBPK with the #OSPSuite by @EstherYun8 @AndreaEdginton. #MIDD #PKSim #MoBi #pharmacylife #research pubmed.ncbi.nlm.nih.gov/31405354/

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OSP Community @ospsuite

5 years ago

#OSPSuite, an open-source #PBPK software has a regulatory-level automated re-qualification framework to qualify your intended-use scenarios in PBPK. Read more about the OSP qualification framework and how to use it here :github.com/Open-Systems-P… #PKSim #pharmacokinetic

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OSP Community @ospsuite

5 years ago

"A Mechanistic, Enantioselective, Physiologically Based Pharmacokinetic Model of Verapamil and Norverapamil, Built and Evaluated for Drug–Drug Interaction Studies" A new publication on #DDI #PBPK with the OSP-Suite #PKSim #MoBi #MIDD mdpi.com/1999-4923/12/6…

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OSP Community @ospsuite

5 years ago

We are happy to announce a new publication on #PBPK with the OSP-Suite (#PKSim #MoBi) "Physiologically‐Based Pharmacokinetic Modeling for the Prediction of CYP2D6‐Mediated Gene–Drug–Drug Interactions" via ascpt.onlinelibrary.wiley.com/doi/full/10.10… #OSPSuite #MIDD

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Nina Hanke @hanke_nina

5 years ago

Excited to share our new Verapamil #PBPK model! mdpi.com/744276 via @MDPIpharma Model files are freely available: github.com/clinical-pharm… #OpenScience @ospsuite #PKSim #MID3

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OSP Community @ospsuite

5 years ago

We are happy to announce a new publication on #PBPK and #QSP with the OSP-Suite (#PKSim #MoBi) "A Physiologically‐Based Quantitative Systems Pharmacology Model of the Incretin Hormones GLP‐1 and GIP and the DPP4 Inhibitor Sitagliptin" #OSPSuite #MIDD ascpt.onlinelibrary.wiley.com/doi/full/10.10…

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OSP Community @ospsuite

7 years ago

Poster at PAGE 2018: A Physiologically-based Quantitative Systems Pharmacology model of the incretin hormones GLP-1 and GIP Check it out here: github.com/Open-Systems-P… #pbpk #opensource #pksim #mobi #ospsuite

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OSP Community @ospsuite

7 years ago

Poster at PAGE 2018: A technical concept of automatic PBPK platform (re-)qualification in the Open Systems Pharmacology Suite (PK-Sim® and MoBi®) Check it out here: github.com/Open-Systems-P… #pbpk #opensource #pksim #mobi #ospsuite

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OSP Community @ospsuite

7 years ago

We just released the 7.3.0 version of the Open Systems Pharmacology Suite including PK-Sim and MoBi. See annoucement github.com/Open-Systems-P… You can download the setup at setup.open-systems-pharmacology.org #pbpk #opensource #pksim #mobi #ospsuite

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OSP Community @ospsuite

8 years ago

A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim. github.com/Open-Systems-P… This model is available in Version 7.2