CC324. We would like to know your opinion. FNAB of a PET+ cervical node in an older man with multiple cutaneous squamous cell carcinomas and actinic lesions on the head. A case from my dermatopath/cytopath junior colleague @pattmh Thanks PET, if it wasn't for you... #cytopath
Part 2. ☹️for the delay, problems with the🔬. We agree, and consider it a case of DERMATOPATHIC LYMPHADENITIS ✍️⬆️large dendritic-like looking cells, single or in clusters, with nuclear grooves. Different from germinal center cells and granulomas ✍️Melanophages, eosinophils
@pepeheffernan @pattmh @AmparoBenito @Quique_rs @Ana08961135 @OKCPathguy @HubertLauMD @israhkhan @kis_lorand @atman_ci @JaylouVelez Probably dermatopathic lymphadenopathy. No evidence of carcinoma, and I don't think these cells are atypical enough to think of melanoma. The pattern of the small mature lymphocytes and admixed histiocytes isn't reminiscent of a lymphoma.
@pepeheffernan @pattmh @Quique_rs @Ana08961135 @OKCPathguy @HubertLauMD @israhkhan @TotalCytopath @kis_lorand @atman_ci @JaylouVelez I see lots of dendritic cells in there... one of them with presumed intracytoplasmic pigment. My first diagnosis is dermatopathic lymphadenopathy. Thanks for the tag, Pepe. Superb pics, as usual!
@pepeheffernan @pattmh @AmparoBenito @Quique_rs @Ana08961135 @OKCPathguy @HubertLauMD @TotalCytopath @kis_lorand @atman_ci @JaylouVelez Can be follicular dendritic cells (snow man cells) /so uniformly distributed but with so much sun damage would def look carefully for any evidence of melanoma,squamous cell carcinoma or Merkel cell carcinoma 🙌🙏
@pepeheffernan @pattmh @AmparoBenito @Quique_rs @Ana08961135 @OKCPathguy @HubertLauMD @israhkhan @TotalCytopath @kis_lorand @atman_ci @JaylouVelez Dendritic cells and Langerhans cells.