Ending 2023 in style: Hsp90-Independent cochaperone-mediated regulation of Tau aggregation: fantastic work from Pijush Chakraborty
doi.org/10.1101/2023.1…
A direct link between Tau phosphorylation by GSK3beta, #Tau condensation and #AlzheimersDisease 's Disease Tau Fold: stellar work from Pijush Chakraborty in collaboration with the lab of Ben Wolozin biorxiv.org/content/10.110…
Acetylation fuels aggregation of three-repeat tau yet slows that of four-repeat tau. Why? Acetylated lysines in a segment unique to 4R tau disrupt fibril cores. @DZNE_en ow.ly/bbRK50PUbkb
Why does only 3R Tau form insoluble deposits in Pick's disease? Stellar work from Pijush Chakraborty shows that acetylation promotes aggregation of 3R Tau but blocks aggregation of 4R Tau.
nature.com/articles/s4146…
Chandrayaan-3 Mission:
'India🇮🇳,
I reached my destination
and you too!'
: Chandrayaan-3
Chandrayaan-3 has successfully
soft-landed on the moon 🌖!.
Congratulations, India🇮🇳!
#Chandrayaan_3#Ch3
Spearheaded by Taekyung Yu, we show how synaptogyrin shapes synaptic vesicles to allow for precise storage of neurotransmitters nature.com/articles/s4159…
Science is hard.
Good research makes you feel stupid.
You're inadequate for the task at hand.
How else would it be? You're pushing the boundaries of knowledge.
Get used to it. This process is immensely rewarding.
It was wonderful to have Markus Zweckstetter @mz_science visit us @IiserMohali. So nice to see a jam-packed hall during his seminar on a Saturday. Had invigorating discussions on condensates. Thanks, Markus, for visiting us. We greatly enjoyed your visit, talk, and interactions.
The chaperone protein FKBP12 binds to aggregate-prone segments of tau, preventing neurofibrillary tangles and neurodegeneration in three-dimensional human neuron-astrocyte cell cultures. @BU_Tweets @DZNE_en ow.ly/JAeF50MJEa2
Glad to virtually meet @SamratLabMohali after five years. Excellent people and great science! It was a perfect way to spend the home quarantine. Hopefully, we can meet in person soon 🙂
Glad to virtually meet @SamratLabMohali after five years. Excellent people and great science! It was a perfect way to spend the home quarantine. Hopefully, we can meet in person soon 🙂
We are excited about our 4th annual lab symposium on December 19 (Sunday).
Looking forward to the annual reunion and talks of former and current members (hybrid mode).
We will also launch our new & exciting lab website on the 19th (we are currently working on it). Stay tuned😀
Been working on this model for a while, and after several iterations and some help from the wonderful NMR staff at UW Madison, it is finally done.
Check out Nuclear Magnetic Resonance Instrument by Michael.Aristov in #3D, #VR or #ARskfb.ly/oqoLw via @Sketchfab
22K Followers 7K FollowingA women of 21st Century. Founder of a NGO which works for Helpless Street Children,we also do other community services. #RadheKrishna #BharatFirst #JaiShriRam
10K Followers 2K FollowingTrying to understand the Developmental Biology of vertebrate limb.
In BMP I trust!
All tweets are personal . RTs are not endorsements.
314 Followers 262 FollowingAssistant Professor, Department of Chemistry, @IITkgp; Former faculty @IITISM_Dhanbad; Former postdoc @MIT, @uOttawa; PhD @purdue university; BS-MS @IiserMohali
466 Followers 1K FollowingPostdoctoral researcher at @fz_juelich, interested in amyloid aggregation processes and the study of their structures by cryo-EM
22 Followers 1K FollowingI live alone now and enjoy business, traveling, shopping, food and music. I have a calm personality and I hope we can be friends.
55 Followers 177 FollowingPDF in Med. Chem. @Saarland University (Prof. Uli Kazmaier)/Close-up magician/ Guitarist. Ph.D.@ IITM (Prof. G. Sekar)/past:PDF@Goettingen (Prof. L. F. Tietze)
829 Followers 877 FollowingAssistant Professor
Dept. of Chemistry,
Indian Institute of Technology-Guwahati (IITG),
Former PDRA@MIT, Boston. Former AvH Fellow@University of Gottingen.
275 Followers 626 FollowingSynthetic Organic Chemist; In quest for Sustainable Catalysis; Interested in complex biologically active molecule synthesis through catalysis
26K Followers 3K Followingfor my code&fonts → @MFEKglif
jail Watkins²🚔
pfp—@maaudaan_tg
NSFW
jim wants to kill me cuz i caught him fake Q'ing
“an oddly imposing figure”—@guardian
15K Followers 2K FollowingProtein and coffee lover, father of two, professor of biophysics and sudo scientist at the #LinderstrømLang Centre for Protein Science 🇩🇰
247 Followers 418 FollowingSenior Research fellow at the University of Massachusetts Amherst with Professor Lila M. Gierasch and Dr. Jennifer Rauch. Fascinated by the protein world!
1K Followers 719 FollowingAssistant Professor, Department of Chemistry, @iiserbhopal. PI of Chemical Synthetic Biology Lab. Alumnus of @Stanford @StanfordCIGH @UCSanDiego @IITKgp
10K Followers 2K FollowingTrying to understand the Developmental Biology of vertebrate limb.
In BMP I trust!
All tweets are personal . RTs are not endorsements.
466 Followers 1K FollowingPostdoctoral researcher at @fz_juelich, interested in amyloid aggregation processes and the study of their structures by cryo-EM
181K Followers 1K FollowingCutting-edge news & reports from PNAS, one of the world's most-cited scientific journals, sibling journal of @PNASNexus & an official journal of @theNASciences.
404 Followers 41 FollowingAll the institutions where I have been to: IIT Kanpur, UofRochester, UPenn, Cornell, and my workplace TIFR, have trained me to ask "why?", and assert "why not!"
314 Followers 262 FollowingAssistant Professor, Department of Chemistry, @IITkgp; Former faculty @IITISM_Dhanbad; Former postdoc @MIT, @uOttawa; PhD @purdue university; BS-MS @IiserMohali
6K Followers 5K FollowingProfessor of Structural Molecular Biology & Director of @AstburyCentre at @UniversityLeeds. Friends, family & #CryoEM. Views def my own!
829 Followers 877 FollowingAssistant Professor
Dept. of Chemistry,
Indian Institute of Technology-Guwahati (IITG),
Former PDRA@MIT, Boston. Former AvH Fellow@University of Gottingen.
98 Followers 119 FollowingPh.D. student at Ak Meyer in University of Goettingen. @AKMeyer_Goe @uniGoettingen
#daadfellow
#BENCh
Master thesis: @osml5
BSMS: @chm_iiserb
55 Followers 177 FollowingPDF in Med. Chem. @Saarland University (Prof. Uli Kazmaier)/Close-up magician/ Guitarist. Ph.D.@ IITM (Prof. G. Sekar)/past:PDF@Goettingen (Prof. L. F. Tietze)
120K Followers 1K FollowingWe no longer post on this account, but it remains active for monitoring purposes. See our pinned post below for other channels where you can find us.
275 Followers 626 FollowingSynthetic Organic Chemist; In quest for Sustainable Catalysis; Interested in complex biologically active molecule synthesis through catalysis
140 Followers 111 FollowingSunita Sanghi Centre of Aging & Neurodegenerative diseases (SCAN)
Data.Device.Detection
A Journey to Combat Neurodegenerative Diseases.
66K Followers 102 FollowingScience Advances is an open access journal from AAAS that publishes innovative original research across all disciplines of science freely to a global audience.
1.2M Followers 745 FollowingStand-up comedian, Story-teller, live show tickets: https://t.co/2guAPCsXm0 for booking : [email protected] baadal Important hain
47K Followers 999 FollowingOfficial account German Embassy to India & Bhutan. Ambassador @AmbAckermann. Retweets≠endorsements. No Visa queries. Imprint/data privacy: https://t.co/oMWMI4dy3a
31K Followers 620 FollowingIndiaBioscience serves as a catalyst for facilitation and change in the life sciences ecosystem in India. 🇮🇳 Curated by @moumimazumdar & @sreshthamondal
2K Followers 369 FollowingLive in the sunshine where you belong.
#immunology #allergy #asthma #allergicdiseases #clinicalimmunology #immunesystem #immunooncology
2K Followers 453 FollowingAssociate Professor at IIT Jodhpur, INSA Young Associate & EMBO Global Investigator. Leading a team of enthusiasts interested in amyloid biology.
2K Followers 789 FollowingGroup leader at @MRC_LMB working to understand the molecular mechanisms of neurodegenerative diseases (formerly Benjamin Falcon)
15K Followers 2K FollowingProtein and coffee lover, father of two, professor of biophysics and sudo scientist at the #LinderstrømLang Centre for Protein Science 🇩🇰
1K Followers 851 FollowingMRC Clinician Scientist and Honorary Consultant Neurologist at UCL Queen Square Institute of Neurology and The National Hospital for Neurology and Neurosurgery