Vladimir Kubyshkin @polyproline
Physical organic chemistry, fluorine, amino acids, peptides and more currently at Enamine Ltd, Ukraine orcid.org/0000-0002-4467… Ukraine Joined August 2021-
Tweets173
-
Followers68
-
Following46
-
Likes388
A whole panel of 5-spirocyclic proline analogues prepared by colleagues from Enamine doi.org/10.1039/D4OB01…
Another amazing work from the group of JC Horng, unveiling the effects of cation-pi interactions in the assembly of the collagen triplex doi.org/10.1021/acs.jp…
A fold stabilizing effect of a proline analogue on a 36 residues miniprotein doi.org/10.1038/s42004…
Few interesting heteroatomic proline analogues in collagen mimetics. Seems that 5-oxaproline is well tolerated and accelerates the triple helical assembly. Great work! doi.org/10.1039/D5OB00…
Aromatic caps at the termini promote stability to triple helix in collagen mimics with just 4-6 GPO repeats doi.org/10.1021/acs.bi…
The importance role of central proline to the antimicrobial potency and selectivity of indolicidin doi.org/10.1007/s00203…
I'm not a computational chemists, but would like to thank Prof Karplus for his work on rotation around peptidyl-prolyl amide bond, where they identified the major rotation pathway, and introduced the rotation transition state nomenclature. Merci!
I'm not a computational chemists, but would like to thank Prof Karplus for his work on rotation around peptidyl-prolyl amide bond, where they identified the major rotation pathway, and introduced the rotation transition state nomenclature. Merci!
I got a couple of new postcards from Genova and Berlin. Thank you for the Christmas cheer, Lars! Happy 2025, everyone! I hope for a better year for all of you. Let your efforts pay off this year, my dear friends! 🍾🥂🎄🥳
Really good article published few months ago about the choice of linker for drug macrocyclization. Many clever ideas. doi.org/10.1021/acs.jm…
Here is a nice new article on fluoroproline labelling of huntingtin protein and subsequent 19F NMR: doi.org/10.1002/chem.2… As we speculated in our Chem Rev article, this type of labelling could make sense in proline-rich or polyproline domains, which is the case here.
'Widespread Misinterpretation of pKa Terminology for Zwitterionic Compounds and Its Consequences' from Journal of Chemical Information and Modeling (@JCIM_JCTC) is currently free to read as an #ACSEditorsChoice. 📖 Access the full article: go.acs.org/bT5
A deep dive into the biochemistry of azetidine-2-carboxylic acid aimed to reveal toxic effects of this noncoded proline analogue on humans and other species. It's a little funny to see how much more intensively this molecule was researched back in the past doi.org/10.1016/j.tox.…
New spirocyclic proline analogues via a robust synthesis approach. doi.org/10.1021/acs.jo…
Our dedicated review on the use of proline analogues in drug design focusing on the past 15 years of development, and containing suggestions for the future. With Pavel @MykhailiukChem ASAP article in #JMedChem Check it out, it's really interesting! pubs.acs.org/doi/10.1021/ac…
Thank you @TheRubiniGroup for the cute postcard from Nagoya, Japan! I hope you enjoyed the CPS Meeting you attended and the view of mount Fuji 🗻 I really appreciate it. It almost feels like I can travel again 😁
C-Terminal Decarboxylation of Proline-Derived Building Blocks for Protein-Binding Peptides (Hans-Guenther Schmalz and co-workers). #OpenAccess thanks to #ProjektDEAL. @PascalEngel37 @rtg_reloc onlinelibrary.wiley.com/doi/10.1002/ch…
Amazing recent work on presudoprolines forming polyproline-2 helix by Greg Chaume and the team! Another one polyproline-2 crystal structure to the existing collection. doi.org/10.1039/D4CC02…
Our recent review with @TheRubiniGroup provides lots of useful info for those who wanna dive in the world of proline analogues. I wish I had something like that as a student when I was just entering the field. Check it out, folks: doi.org/10.1021/acs.ch…
Memory effects in long polyproline polymers: doi.org/10.1002/anie.2…
Stability of the collagen triple helix relies not only on the length of the sequence but the starting residue matters two, bringing in as much as 10 °C in the thermal stability. doi.org/10.1039/D2SC03…
Alkemix_Fine_Chemical... @Alkemix_FCH
0 Followers 18 Following ALKEMIX® – SOLUTIONS FOR CUSTOM SYNTHESIS – CONTACT US AND HAVE IT DONE!
Madson Aragão @madsondeluna
392 Followers 486 Following PhD Student in Bioinformatics. Interested in Machine Learning, Genetics and Protein Design. All opinions/views are my own. #FirstGen 🧬
Anton.Zhemera @AZhemera
11 Followers 140 Following Journeys through chemical space, navigating some drug-like regions.
Bioisosteres Ltd @bioisosteres
10 Followers 87 Following exploring the cutting-edge science of (bio)isosteres in synthesis and drug development to shape the future of medicine.
Christian C. Carmona-... @ccamiloc30
638 Followers 5K Following Postdoctoral research associate @insarouen | Interested in synthetic chem methodology and suprachem | Ph.D @unistra | MSc. @ufscaroficial | B.S @UnivalleCol.
Southwest Chemist @SW_chemist
85 Followers 205 Following
Rubén Miguélez @MorenRmm
583 Followers 863 Following PhD candidate @PbLabUniOvi ⚗️ Bromoalkynes with Gold (I) Catalyst: C—|—H 🧩 Visiting Student @group_Levin 🇺🇸 Fanatic of spirocycles and skeletal editing.
Volodymyr Shvadchak @Vovaximk
30 Followers 123 Following
Radwan alnajjar @RadwanCADD
15 Followers 307 Following Assistant Professor at UOB and Head of the CADD unit at LIMU, Libya 🇱🇾
Andrew L @halogentleman
7 Followers 190 Following Organic chemist who likes to use computational chemistry to understand what in the molecules is going on?!?
Honggen Wang @Honggen_W
674 Followers 971 Following Professor of synthetic organic chemistry at Sun Yat-Sen University, China
Stephan Hacker (inact... @StephanHacker2
5K Followers 2K Following Inactive account. Find me at: @stephanhacker2.bsky.social @[email protected] https://t.co/kPr9QkAN2S
Игорь Витру... @igor_vitruk
6 Followers 57 Following
Max Schreier @MaxSchreier00
5 Followers 150 Following
Jordy Homing Lam @LamJordy
285 Followers 2K Following Bioinformatics PhD. Compute with 📝 ,🗑️and 🦆. Patron 📚. Wanderer of Chemical Space. Croucher Postdoctoral Fellow.
Luisi-Lab @Luisi_Lab
1K Followers 631 Following Renzo Luisi - Professor of Organic Chemistry #Uniba, Flow Chemistry, Organolithium Chemistry, Fluorinated Molecules, Heterocyclic Chemistry, Nitrogen Transfer
Susan Wu @Suzywu921123
174 Followers 2K Following Technical Sales Manager at RWD Life Science,Animal Model/In Vivo Imaging/Neural Signal/Cellular & Molecular Biology/Pathology ([email protected])
Tomas Fiala @TomFiaLAB
590 Followers 393 Following Senior Scientist and Branco Weiss Fellow at ETH Zürich | Supramolecular Chemistry and Chemical Biology
Matteo Pollastrini @MattePolla
78 Followers 267 Following PhD student Organic Chemistry, Peptides and Self-Assembly
FluorineDivision @FluorineChem
412 Followers 324 Following The Division of Fluorine Chemistry is an active group of scientists who promote their interest in Fluorine Chemistry.
Yuliya Kuchkovska �... @Yu_Kuchkovska
70 Followers 173 Following PhD student at Biozentrum, University of Basel
Mikhail Kovalchuk @mishakov25
0 Followers 18 Following Nothing's special bout me. Just enjoying moment
Jonas Hollemann @JHollemann
7 Followers 51 Following M. Sc. in Chemistry Medical Student @UMGreifswald
TorbeevLab @TorbeevL
217 Followers 366 Following Biosystems Chemistry: Intrinsically Disordered Proteins, Protein Aggregation, Protein Design
Ivan Kondratov @IvanKondratov4
29 Followers 107 Following
Organic synthesis app... @Illia_Ruzhylo
0 Followers 47 Following On a quest to master the arcane craft of organic synthesis. Collecting reactions like spells. Sharing old grimoires & fresh scrolls from the literature
Chris Coxon @Dr_CR_Coxon
2K Followers 1K Following Medicinal Chemist & Chemical Biologist at Uni of Edinburgh - Research in #peptides, #fluorine, #neuro drug discovery 💊. Director @Pep_tec. Cricketer 🏏
Katherine Mirica 🇺... @KMirica
7K Followers 4K Following Associate Professor of Chemistry @Dartmouth, Associate Editor @ACS_Sensors. BS @BostonCollege, PhD @HarvardCCB, Postdoc @ChemistryMIT 🇺🇦🇺🇲
Beilstein-Institut @b... @BeilsteinInst
4K Followers 5K Following Non-profit foundation for the promotion of the chemical sciences. Publisher of Beilstein Journal of Organic Chemistry and Beilstein Journal of Nanotechnology
Agata Starosta @MissAgataStar
1K Followers 1K Following Molecular bacteriologist. Group leader @IBBPAS (previously, Newcastle Uni and LMU Munich). Private account. Views my own.
Alan Aspuru-Guzik @A_Aspuru_Guzik
19K Followers 5K Following Prof. @UofT @VectorInst @CIFAR_News AI Chair & Fellow. C150 Chair. @acceleration_c @digital_discovery
Jean-François Paquin @jfluorine
997 Followers 1K Following Full Professor, Département de chimie, Université Laval, Québec, Canada.
Mariam Odetallah @MariamOdetallah
87 Followers 238 Following PhD student at U of M Electrochemistry ⚡🧪 Rechargeable Batteries 🔋🔌 Imaging Techniques 📸🎥📹
Ivo Dias ⌬ @iesdias
41 Followers 136 Following Invited Assistant Professor @ FCUP | Researcher @ LAQV/REQUIMTE | Organic and Medicinal Chemistry | Focus on Neurodegenerative Diseases
DynaTRAP Project @Dyna_TRAP
1 Followers 7 Following
Hussain Kashif @akhons_chemist
209 Followers 2K Following #supramolecular_Chemistry.#organic. #Synthesis. #Drug_Delivery. #Biomaterials. #Nanomaterials. #Nanocarrier. #2D_Materials. #Boronchemistry.#SEM.#TEM.#AFM
SUPRACHEM-UMU @SuprachemU
334 Followers 600 Following Supramolecular Chemistry Group Departamento de Química Organica, Facultad de Química Universidad de Murcia
José Luis Esquivel @JLesquivel_88
320 Followers 1K Following PhD in Organic Chemistry from the University of Murcia 🇪🇸 🇪🇺
Nikolaj Koch @KochNikolaj
147 Followers 1K Following Scientist @nash_lab, previously @BudisaNed and @rappsilberlab | synthetic biology | genetic code expansion | economics enthusiast
Zondlo Lab @ZondloLab
1K Followers 1K Following Chemical biology/bioorganic chemistry and other such shenanigans. Ruthless multidisciplinarians.
Patrick van der Wel @p_vanderwel
1K Followers 1K Following Solid-state NMR @ Univ. Groningen, biochemistry, amyloid, Huntington disease, membrane biophysics, (bio)materials, carbohydrate; posts=personal, Now BlueSky
Marina Rubini @TheRubiniGroup
822 Followers 243 Following Chemical biologist at @UCD_Research keen to unveil biological processes at a molecular level. Italo-German working in Dublin with an international group.
drug hunter @drughunter_com
11K Followers 26 Following the science of drug discovery, distilled for industry innovators. discover more by subscribing at: https://t.co/FnfsOmSXe4
Retraction Watch @RetractionWatch
91K Followers 20 Following Daily newsletter https://t.co/T4dNEAd2zy Database https://t.co/Wx3LmYCtGk Tips [email protected] (better than @ replies) Donate https://t.co/qh4sIBw1uU
Saranphong Yimklan @SaranphongY
169 Followers 498 Following Assistant Professor in Inorganic Chemistry at Chiang Mai University, THAILAND
Ivan Kondratov @IvanKondratov4
29 Followers 107 Following
Sebastian Riedel @RiedelLab
1K Followers 247 Following Fluorine Chemistry, Sustainable Halogen Chemistry, Greenhouse Gas Replacments, Peroxide’s, Redox Flow Batteries, Superacids, Alkylation, Ionic Liquids ...
FluorineDivision @FluorineChem
412 Followers 324 Following The Division of Fluorine Chemistry is an active group of scientists who promote their interest in Fluorine Chemistry.
Beilstein-Institut @b... @BeilsteinInst
4K Followers 5K Following Non-profit foundation for the promotion of the chemical sciences. Publisher of Beilstein Journal of Organic Chemistry and Beilstein Journal of Nanotechnology
Bits of Jupiter @bitsofjupiter
128K Followers 21 Following A bit of Jupiter every day. Images were taken by the @NASAjuno project. An X bot by @oblgoth
Dirk Schulze-Makuch @extreme_microbe
2K Followers 1K Following An astrobiologist in the search for life in the Universe
SilaPro @SilaPro_
8 Followers 20 Following SilaPro aims at the development of Novel Chemical Strategies to Manage Parkinson's Disease
Jean-François Paquin @jfluorine
997 Followers 1K Following Full Professor, Département de chimie, Université Laval, Québec, Canada.
Truong Thanh Tung @tungpharma
10 Followers 1 Following Ph.D @uni_copenhagen, Postdoc @PittTweet University of Pittsburgh, Assoc. Prof. @PHENIKAA Former Postdoc @AarhusUni, Visiting PhD @helsinkiuni, Alumni @SNUnow
Gellman Lab @bondamidebond
704 Followers 152 Following Samuel H. Gellman Professor and Chair @UWMadisonChem The name is Bond, Amide Bond. Account managed by students.
Daryl Yee @dryeeseeks
6K Followers 943 Following Assistant Professor @EPFL_en | Laboratory for the Chemistry of Materials and Manufacturing (@ALCHEMY_EPFL)
Marina Rubini @TheRubiniGroup
822 Followers 243 Following Chemical biologist at @UCD_Research keen to unveil biological processes at a molecular level. Italo-German working in Dublin with an international group.
China Science @ChinaScience
2.0M Followers 10 Following Timely updates info on advanced technology and scientific progress in China. Run by @PDChina, the largest newspaper group in China
Dr. Dmitry Belov @Dmitry_S_Belov
398 Followers 1K Following Father, scientist. Organic chemist by training. Now working on siRNA delivery
TorbeevLab @TorbeevL
217 Followers 366 Following Biosystems Chemistry: Intrinsically Disordered Proteins, Protein Aggregation, Protein Design
nmr_spectroscopy / Or... @NMRspectroscopy
11K Followers 176 Following Andrii Kozytskyi, Ph.D. 🧲🧪📝Small molecules NMR 📚Theory and practice 🟢only useful information in the feed 🔴no scientific trash #nmr #nmrchat #chemistry
Oleksandr Grygorenko ... @DrGregor2
627 Followers 181 Following Head of OrgChemDept at Taras Shevchenko Natl. University of Kyiv. Consulting scientist at Enamine Ltd. Chemical journalist(c). Huge fan of prog metal/rock
Mingxia Guo @MingxiaGuo
81 Followers 113 Following
Suessmuth Lab @Suessmuth_Lab
1K Followers 366 Following #naturalproducts #peptides #synthesis #biosynthesis Run by members of the Biological Chemistry Department of @TUBerlin.
Wenhao Sun @sunwh1908
22 Followers 164 Following
Tam Dang @tam_dang19
93 Followers 153 Following Research and Technical Scientist in @Suessmuth_Lab at @TUBerlin. Research on virulence factors of P. larvae.🐝 Interest in natural products. Street food lover.
Agata Starosta @MissAgataStar
1K Followers 1K Following Molecular bacteriologist. Group leader @IBBPAS (previously, Newcastle Uni and LMU Munich). Private account. Views my own.
Organic Syntheses @OrgSynth
11K Followers 53 Following Since 1921, Organic Syntheses has provided the chemistry community with detailed, reliable, & carefully checked procedures for syntheses of organic compounds.
Mankin_Vazquez_Lab @shuramankin
302 Followers 30 Following
IBC Academia Sinica @IBCSinica
541 Followers 398 Following Institute of Biological Chemistry Research: 1)Host-Microbe Interactions, 2)Cell Homeostasis, 3)Intracellular-Extracellular Communication, 4)Synthetic Biology
NMRbox @NMRbox
557 Followers 10 Following Simplifying choosing, using, and archiving NMR software for bio-NMR
Margaret Brimble @BrimbleM
4K Followers 2K Following Medicinal chemistry molecule maker! Mother of Trofinetide/NNZ2566 FDA approved drug for Rett Syndrome tradename Daybue - Neuren/Acadia Pharmaceuticals
Brimble Lab @Brimble_Lab
1K Followers 240 Following Twitter account for Brimble Lab organic synthesis and peptides research at The University of Auckland | student run
Ignatova Lab @IgnatovaLab
2K Followers 671 Following A lab of #RNA lovers, obsessed with tRNA, translational control in protein biogenesis and disease. #translation #ribosome #mRNA #tRNA #SNP 🇺🇦
OBC @OrgBiomolChem
9K Followers 720 Following This account has been archived. Stay connected with us on https://t.co/JXp8owStcT, Bluesky and LinkedIn.
Glenn Facey @uOttawaNMR
4K Followers 572 Following Glenn Facey, Retired NMR Facility Manager, University of Ottawa. All tweets are my own and do not represent uOttawa.
Ingo Wohlgemuth @WohlgemuthIngo
146 Followers 307 Following Biochemist in the Rodnina lab @mpi_nat Fidelity of protein synthesis by quantitative mass spectrometry
WilsonLab @WilsonLab2
2K Followers 485 Following Ribosomes & Translation Regulation; Antibiotics & Resistance Mechanisms; Structural Biology & Cryo-EM; University of Hamburg.
Dr Fluorine @DrFluorine
1K Followers 626 Following
Ned Budisa @BudisaNed
162 Followers 142 Following Professor of Chemistry & Tier 1 Canada Research Chair in Chemical Synthetic Biology and Xenobiology
Zondlo Lab @ZondloLab
1K Followers 1K Following Chemical biology/bioorganic chemistry and other such shenanigans. Ruthless multidisciplinarians.
Mykhailiuk Chem 🇺�... @MykhailiukChem
2K Followers 20 Following
Andrei Yudin @andrei_yudin
8K Followers 1K Following Prof at U Toronto. Associate Editor for @ChemicalScience. Trying to understand the universe.Trends for United States
You might like
