ProteinQure @proteinqure
Canadian biotech startup for peptide drug design employing next-generation methods (biophysical modelling, machine learning, and high-throughput experiments) proteinqure.com Toronto, Ontario Joined October 2017-
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Excited to announce that our CEO @lucasfolds, Lucas Siow, is currently attending the @bloomburton Healthcare Investor Conference in Toronto. We're eager to meet with investors, partners, and scientists. Reach out about #oncology, drug delivery, or #peptides! #BBHIC2024
📅 Mark your calendars for April 9, 2024, for our detailed presentation at #AACR2024. Stay with us for more updates and breakthroughs. Together, we're moving closer to revolutionizing cancer therapy with targeted treatments! tinyurl.com/PQInc #ProteinQure #CancerResearch
Our innovative tumor-targeting Peptide Drug Conjugate is moving to IND-enabling studies & clinical trials, demonstrating powerful antitumor efficacy, even in chemoresistant cancers. This marks a milestone for our computational drug design platform. tinyurl.com/PQInc
This week our co-founder Chris (@jsci) is attending the Chemistry and Biology of Peptides GRC in Ventura, CA. We're pleased to share progress on the development of our peptide-drug conjugate program; and how our structure-based drug design platform enabled its discovery.
At our last quarterly on-site, we brought together a panel of speakers—a professor, a patient, a clinician, and an industry leader—for discourse on different facets of drug development. Their stories provided invaluable context for our mission, aligning purpose with perspective.
Our CEO, Lucas Siow @lucasfolds, will be attending JPM this year. We look forward to connecting with investors, partners, and scientists to start off an exciting year. Reach out if you'd like to talk about #oncology, drug delivery, or anything about #peptides #JPM24
Happy Holidays from ProteinQure! Looking back, we've had a wonderful year with achievements across both internal and external programs, and novel platform R&D like PQ Librarian. We can't wait to share more in the upcoming press releases of the new year!
We're sharing updated data on our oncology program in triple-negative breast cancer at the San Antonio Breast Cancer Symposium today. We're thankful to be part of such an active community of researchers seeking new therapeutic options for patients with few options. #SABCS23
Last week, our CSO @jsci spoke as a panelist on medical innovation at #BioTEC 2023. It's inspiring to speak to a room full of ambitious young scientists eager to make an impact in human health across so many disciplines @thisisbiotec
Breast cancer is a complex disease with unique subtypes. As part of #BreastCancerAwarenessMonth our latest blog post explores the science behind HER2, ER, and PR receptors. Together, we're making strides in the fight against breast cancer! tinyurl.com/pq-bcam
Today marks our 6th anniversary! Thanks to the team, our advisors, investors, partners, and everyone else who supported us in our efforts to build the future of peptide therapeutics. #AIDrugDiscovery #AIProteinDesign #ProteinDrug #Peptides #CADD #PeptideTherapeutics
This week our co-founder @jsci gave a talk at the Next-Generation Protein Therapeutics Summit 2023. The next-generation lies at the intersection of novel scaffolds, improved drug-like properties, and increased safety #proteinsummit
We're excited to welcome Maryna to the team to help drive the discovery of next-generation peptide therapeutics!
Check out the latest interview with our co-founder @mark_fingerhuth to learn more about how we cultivate a culture of innovation at ProteinQure.
Check out the latest interview with our co-founder @mark_fingerhuth to learn more about how we cultivate a culture of innovation at ProteinQure.
Guillaume Verdon @GillVerd
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Our innovative tumor-targeting Peptide Drug Conjugate is moving to IND-enabling studies & clinical trials, demonstrating powerful antitumor efficacy, even in chemoresistant cancers. This marks a milestone for our computational drug design platform. tinyurl.com/PQInc
ProteinQure (CDL'18) has announced a significant breakthrough in the fight against triple-negative breast cancer. @proteinqure's development of a novel Peptide Drug Conjugate has demonstrated effectiveness across a range of patient-derived mouse models. biospace.com/article/releas…
Big milestone at @proteinqure regarding our targeted therapeutic against triple-negative breast cancer! I'm incredibly proud of our entire team and excited to keep working towards our first clinical trial.
Our innovative tumor-targeting Peptide Drug Conjugate is moving to IND-enabling studies & clinical trials, demonstrating powerful antitumor efficacy, even in chemoresistant cancers. This marks a milestone for our computational drug design platform. tinyurl.com/PQInc
Share your team's progress via a biweekly digest Every two weeks I wrote and shared a "DSE Digest" to our VPs and C-suite. This cadence aligned with our sprint length and balanced speed with substance. I covered 5-7 topics per digest, and eventually we used our corporate goals…
Prepare for friction from legacy systems, file formats, & workflows Many people in biotech operate default private, whereas tech is default public. Closed-source vs open-source. Secrets, risk management, compliance vs accessibility, openness, sharing. Legacy vs modern. Local vs…
Biotech and Tech people use different vocabulary and mental models Biotechs employ scientists, accountants, manufacturing specialists, lab managers, lawyers, medical affairs specialists, software developers, etc. It is a naive mistake to think everyone shares an understanding of…
Build? Buy? Some of both? Your decision to build versus buy depends on how your firm generates value, what you promised your investors, who you hired (and who you have to work with but didn't hire), the culture at your firm, and what tools are available. We built a lean, focused…
Conduct monthly retrospectives with your team to reflect and learn Every month, my team met (over Zoom) to hold a retrospective (retro, for short). We covered three topics: 1. Rose - what is going well? 2. Thorn - what is going poorly? 3. Bud - what should we change? I opened…
Biotechs care about scientific or clinical results, not platforms You care about your platform. The potential impact and efficiency of scaling the same analyses across multiple scientific programs is obvious. Unfortunately, everyone else at your biotech is most likely…
Background In early 2021 I joined Prometheus Biosciences, a small biotech startup, as an early employee and the head of data science and software engineering ("DSE"). Our mission was to develop precision therapeutics for autoimmune disease, with an initial focus on inflammatory…
What I learned leading a data science & software team in biotech You You are a technical leader at a biotech startup. Your title is Director, or VP of Data Science / Machine Learning / Engineering, or CTO / CDO. Your remit is to develop a "platform" or "engine", an exciting…
Exciting to see more attention drawn to SORT1. We're looking forward to sharing results from our sortilin-mediated drug delivery platform, with novel, high-affinity targeting ligands and the best siRNA delivery data to date
Transforming drug delivery: New research reveals galectin-1's pathway into cells via sortilin, offering a novel approach for siRNA and protein therapeutics. This insight could revolutionize targeted drug discovery.
We had a blast building this interface to our first publicly released machine learning model. You can use PQ Librarian to predict the likelihood of obtaining specific hits when screening a combinatorial peptide library. More exciting things to come soon, stay tuned!
Introducing @proteinqure Librarian: An innovative AI tool for peptide drug discovery! Simplify your search with color-coded scores for peptide libraries. Perfect for early-stage drug discovery efficiency. #PeptideLibraries #PhageDisplay #LLM tinyurl.com/pqlibrarian
I like to think of this as the four stages of custom LED matrix testing. 😂 I mean, there's obviously many ways to do it. But since this is new to me, I wanted to test as I was going, to make sure I was connecting everything right! I think I got it right. 😎 Stay tuned.
Seeing some qs on what Gemini *is* (beyond the zodiac :). Best way to understand Gemini’s underlying amazing capabilities is to see them in action, take a look ⬇️
@BowTiedBiotech @proteinqure Consider half-life and bioavailability to some tissues as solved (coming from the leaders: Novo and Lily). We're working hard to demonstrate tissue specificity with others. Even without half-life extension strategies like serum albumin binding our team has designed T1/2 > 24hr.
@BowTiedBiotech Our team at @proteinqure has worked exclusively on peptide drug design challenges over the past six years; including half-life. LLMs can play a role to engineer drug-like peptides, but a suite of approaches is required for synthetic peptide design with full chemical complexity
Okay, now this is getting personal... blog.google/products/regis…