radoncreview_org @radoncreview
Our mission is to create the most comprehensively updated Rad Onc reference and to make it available for free, forever, for all. RadOnc.org Joined September 2019-
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radoncreview_org retweeted
Check out the new updates to #RadOncCalc and @RadoncTables available now on all platforms (iOS, Android, web) Rad Onc Tables IOS ➡️ is.gd/tnqpTT Android ➡️ is.gd/dzc9xH Rad Onc Calc IOS ➡️ is.gd/txHOue Android ➡️ is.gd/HzIP5x
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radoncreview_org retweeted
Here is a provocative paper for stage III. This data is suggestive of Rituximab + RT being curative treatment, with none of the 11 patients who received peri-radiation Rituximab experiencing relapse. DLBCL-free survival is a patient-centric endpoint! ncbi.nlm.nih.gov/pubmed/32316464
radoncreview_org retweeted
Rituximab does not decrease transformation to DLBCL. Adding targeted, modern radiotherapy may decreases this ~20% long term risk by an order of magnitude. DLBCL-free survival is a meaningful endpoint for patients. Teamwork is key! 🤝 #LYMSM sciencedirect.com/science/articl…
Rituximab does not decrease transformation to DLBCL. Adding targeted, modern radiotherapy may decreases this ~20% long term risk by an order of magnitude. DLBCL-free survival is a meaningful endpoint for patients. Teamwork is key! 🤝 #LYMSM sciencedirect.com/science/articl… https://t.co/5dV1UAB9xL
radoncreview_org retweeted
Seeing some logical fallacies in this debate. It not logically sound to assume that patients who progress on NAC-ICI wouldn’t have responded to upfront chemoradiotherapy.
Seeing some logical fallacies in this debate. It not logically sound to assume that patients who progress on NAC-ICI wouldn’t have responded to upfront chemoradiotherapy.
radoncreview_org retweeted
@NiuSanford @freddyeescorcia Also, radiotherapy can improve Child-Pugh scores from B ➡️ A. Lasley et al. Such a great paper! This fact tends to leave surgeons, IR, and med oncs equally jaw-dropped. Try dropping this fun fact at a GI tumor board near you! pubmed.ncbi.nlm.nih.gov/25899219/
radoncreview_org retweeted
Math checks out with absolute dose! HCC is a rather radiosensitive tumor. Interesting aside: A BED10 of >80 Gy with EBRT yields 80–90% local control. For context, 400 Gy in a single fraction equates to a BED10 of 16,400 Gy—yet the X-axis of this chart maxes out at 150 Gy. Of…
Math checks out with absolute dose! HCC is a rather radiosensitive tumor. Interesting aside: A BED10 of >80 Gy with EBRT yields 80–90% local control. For context, 400 Gy in a single fraction equates to a BED10 of 16,400 Gy—yet the X-axis of this chart maxes out at 150 Gy. Of… https://t.co/mHbLtWS0bs
radoncreview_org retweeted
@NiuSanford @radoncreview @HCCLIVEConf I've never understood Y90 dosimetry. The prescription dose in Gy is so high, ~10x EBRT and ~3x LDR Brachy, despite Y90's half-life being much shorter than prostate LDR isotopes. Why does intravascular therapy require such a massive dose? Does any biologically relevant volume…
radoncreview_org retweeted
Could ensuring a minimum dose to the entire tumor be just as, or even more, critical than ≥ 400 Gy in some areas, especially for larger tumors? Also, is there a way to prospectively guarantee full shoulder coverage, and is this coverage routinely quantified with Y-90? 🧩 #HCC
Is this the most important question? @HCCLIVEConf #HCC 🧩
Is this the most important question? @HCCLIVEConf #HCC 🧩
radoncreview_org retweeted
Until we get clear data - the story for larger tumors and especially MVI is that min dose does matter … I have seen tumor thrombus progress into confluence for example Until dosimetry is clear to interpret ( such as EYE90) along with positive phase 3 trial - onus is on y90…
Until we get clear data - the story for larger tumors and especially MVI is that min dose does matter … I have seen tumor thrombus progress into confluence for example Until dosimetry is clear to interpret ( such as EYE90) along with positive phase 3 trial - onus is on y90…
radoncreview_org retweeted
@NiuSanford @radoncreview @HCCLIVEConf Nope. You need 10% of that, in five fractions. ALARA.
radoncreview_org retweeted
@radoncreview @HCCLIVEConf Thanks Jeff, I think it highlights a good pt that Riad touches upon. Y90 and SBRT dose are measured differently though both in Gy...you don't need 400 Gy to whole tumor in HCC - it's a radiosensitive histology.
radoncreview_org retweeted
@BeauToskichMD @MHadziMD @dr_yakupergun @JournalCancer Completely agree! The key is selecting the best LC modality per patient through multiD decision-making. Dual IR/RO approaches are some of my favorite across any disease site. When total consolidation runs like a well-oiled machine & both hands work together, patients can achieve…
radoncreview_org retweeted
Our meta-analysis comparing EBRT & TACE for HCC is here in @JournalCancer ! (Spoiler: RT benefits patients in LC and PFS) Thank you so much @nbn426 for being such an incredible mentor and guiding me every step of the way on the project! acsjournals.onlinelibrary.wiley.com/doi/10.1002/cn…
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